| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.109516 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.10727 |
| CD44 | CD44 molecule (Indian blood group) | 0.0839 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0823141 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0624906 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0579099 |
| ANXA2 | annexin A2 | 0.0460342 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0440075 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0437422 |
| SDC4 | syndecan 4 | 0.0432867 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0423768 |
| B2M | beta-2-microglobulin | 0.0421242 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394081 |
| VEGFA | vascular endothelial growth factor A | 0.0383382 |
| PRELID2 | PRELI domain containing 2 | 0.0376727 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0370921 |
| KYNU | kynureninase | 0.0358513 |
| HLA-B | major histocompatibility complex, class I, B | 0.034917 |
| FAM13A | family with sequence similarity 13, member A | 0.0345173 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0336382 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0324591 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0319851 |
| NDRG1 | N-myc downstream regulated 1 | 0.030487 |
| STC1 | stanniocalcin 1 | 0.0299524 |
| CALR | calreticulin | 0.0299408 |
| AHNAK | AHNAK nucleoprotein | 0.0295604 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295121 |
| CANX | calnexin | 0.0290533 |
| ARRDC3 | arrestin domain containing 3 | 0.0290165 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0279146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0273422 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0272082 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0259605 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025795 |
| FLNA | filamin A, alpha | 0.0250422 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245234 |
| WTAP | Wilms tumor 1 associated protein | 0.0242896 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0239625 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0234848 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0223014 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.022137 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0212437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0211841 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0211798 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0207094 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0204964 |
| ZNF292 | zinc finger protein 292 | 0.0204385 |
| TMSB4X | thymosin beta 4, X-linked | 0.0202364 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0201326 |
| RPL37A | ribosomal protein L37a | 0.0199709 |
| PKM | pyruvate kinase, muscle | 0.019643 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0194152 |
| MATR3 | matrin 3 | 0.0193801 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0192317 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0189981 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0186419 |
| FNIP1 | folliculin interacting protein 1 | 0.0182835 |
| SP100 | SP100 nuclear antigen | 0.0181863 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0179496 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0176507 |
| ANO6 | anoctamin 6 | 0.0173176 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0172741 |
| RPS27A | ribosomal protein S27a | 0.0169763 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0169192 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0169177 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0167053 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0165725 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0163639 |
| FOSL1 | FOS-like antigen 1 | 0.0162898 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0162506 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0160773 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0160537 |
| MCL1 | myeloid cell leukemia 1 | 0.0160107 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0159193 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0158574 |
| SMAD3 | SMAD family member 3 | 0.0158531 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.01547 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0154345 |
| WWOX | WW domain containing oxidoreductase | 0.0152775 |
| RUNX1 | runt-related transcription factor 1 | 0.0152505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0151346 |
| ASPH | aspartate beta-hydroxylase | 0.0150479 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0149728 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0147092 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.014679 |
| RNF24 | ring finger protein 24 | 0.0146106 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0145423 |
| ECE1 | endothelin converting enzyme 1 | 0.0145123 |
| RPS8 | ribosomal protein S8 | 0.0144949 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0144527 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0141936 |
| HLA-C | major histocompatibility complex, class I, C | 0.0141748 |
| RBM39 | RNA binding motif protein 39 | 0.0141212 |
| MTPN | myotrophin | 0.0140591 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0140239 |
| IL6 | interleukin 6 | 0.0140222 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0140143 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0140089 |
| ZNF395 | zinc finger protein 395 | 0.0139988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A2 | collagen, type I, alpha 2 | -0.0585349 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0516068 |
| TMSB10 | thymosin beta 10 | -0.0488431 |
| COL1A1 | collagen, type I, alpha 1 | -0.0484168 |
| TPM1 | tropomyosin 1 (alpha) | -0.0278377 |
| CDH13 | cadherin 13 | -0.0251256 |
| MT2A | metallothionein 2A | -0.0241024 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0222685 |
| LOX | lysyl oxidase | -0.0203745 |
| COL5A2 | collagen, type V, alpha 2 | -0.0195993 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0194313 |
| EGR1 | early growth response 1 | -0.0171331 |
| MAP4 | microtubule-associated protein 4 | -0.0157489 |
| CDK6 | cyclin-dependent kinase 6 | -0.0157081 |
| TMEM165 | transmembrane protein 165 | -0.0153518 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0153026 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0149795 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0149595 |
| RRBP1 | ribosome binding protein 1 | -0.0148467 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0146099 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0144884 |
| EVI5 | ecotropic viral integration site 5 | -0.0144121 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0142534 |
| PLCB4 | phospholipase C, beta 4 | -0.014158 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0141103 |
| RTN4 | reticulon 4 | -0.0139568 |
| EGFR | epidermal growth factor receptor | -0.0139153 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0138926 |
| ERBIN | erbb2 interacting protein | -0.0138426 |
| POTEF | POTE ankyrin domain family, member F | -0.0137197 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0133278 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0132221 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0131051 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0129433 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0129334 |
| TNNC1 | troponin C type 1 (slow) | -0.0127298 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0126484 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0126147 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0125135 |
| TPM4 | tropomyosin 4 | -0.0125029 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0123421 |
| KAZN | kazrin, periplakin interacting protein | -0.0122734 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0122479 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0122054 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0118632 |
| ARF4 | ADP-ribosylation factor 4 | -0.0116235 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0115341 |
| MAP1B | microtubule-associated protein 1B | -0.0114757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0113689 |
| PARD3 | par-3 family cell polarity regulator | -0.0113403 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0112661 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0111163 |
| RNF145 | ring finger protein 145 | -0.0110546 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0109946 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0108431 |
| WWC2 | WW and C2 domain containing 2 | -0.0108242 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0107658 |
| TUBA1B | tubulin, alpha 1b | -0.0106752 |
| CENPF | centromere protein F, 350/400kDa | -0.0105563 |
| NBEAL1 | neurobeachin-like 1 | -0.0105544 |
| SLFN5 | schlafen family member 5 | -0.0103242 |
| SMYD3 | SET and MYND domain containing 3 | -0.0103202 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0102478 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0102152 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0101896 |
| TAGLN2 | transgelin 2 | -0.0101771 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0101235 |
| SCFD2 | sec1 family domain containing 2 | -0.0101221 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0100844 |
| THOC2 | THO complex 2 | -0.0100462 |
| FAM133B | family with sequence similarity 133, member B | -0.0100147 |
| RAB13 | RAB13, member RAS oncogene family | -0.00991648 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.00971713 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00954545 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.00953238 |
| FRMD4A | FERM domain containing 4A | -0.00952923 |
| CEP350 | centrosomal protein 350kDa | -0.00940701 |
| PDE10A | phosphodiesterase 10A | -0.00933157 |
| CDCA2 | cell division cycle associated 2 | -0.00932875 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.00931872 |
| OSBP | oxysterol binding protein | -0.00930641 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00927804 |
| TRAPPC10 | trafficking protein particle complex 10 | -0.00918087 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | -0.00909276 |
| TLK1 | tousled-like kinase 1 | -0.00904115 |
| AK1 | adenylate kinase 1 | -0.00899691 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.00894006 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00882327 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00876884 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00876647 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.00874449 |
| PRKD1 | protein kinase D1 | -0.00870775 |
| TPX2 | TPX2, microtubule-associated | -0.008673 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00866453 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00858797 |
| KIF1B | kinesin family member 1B | -0.00858543 |
| FBN1 | fibrillin 1 | -0.00853841 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00850936 |
| CA12 | carbonic anhydrase XII | -0.00850904 |
| AGRN | agrin | -0.00850386 |
