| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lonafarnib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lonafarnib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.15966 |
| NRG1 | neuregulin 1 | 0.123365 |
| ASPH | aspartate beta-hydroxylase | 0.0980308 |
| HMGA2 | high mobility group AT-hook 2 | 0.0976149 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0934244 |
| ITGA1 | integrin, alpha 1 | 0.0635904 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0611902 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0530785 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0474498 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0473566 |
| GLIS3 | GLIS family zinc finger 3 | 0.0466872 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0431317 |
| SQSTM1 | sequestosome 1 | 0.0425685 |
| STC2 | stanniocalcin 2 | 0.0414317 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0409713 |
| LOXL2 | lysyl oxidase-like 2 | 0.040179 |
| SMAD3 | SMAD family member 3 | 0.0400332 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0397218 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0395981 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0390495 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0389338 |
| RAI14 | retinoic acid induced 14 | 0.0373918 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0372125 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0359721 |
| EFNA5 | ephrin-A5 | 0.0358213 |
| AHNAK | AHNAK nucleoprotein | 0.0352896 |
| VCL | vinculin | 0.0350993 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0337893 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.033293 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0332315 |
| VEGFA | vascular endothelial growth factor A | 0.0328734 |
| FAT1 | FAT atypical cadherin 1 | 0.0322663 |
| SEPTIN9 | septin 9 | 0.0317202 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0302629 |
| AEBP2 | AE binding protein 2 | 0.0292959 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286043 |
| TMEM156 | transmembrane protein 156 | 0.0284081 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0282585 |
| PALLD | palladin, cytoskeletal associated protein | 0.0281052 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0280646 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0279235 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0277305 |
| SVIL | supervillin | 0.0262871 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0256541 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0256268 |
| ENO1 | enolase 1, (alpha) | 0.0246954 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0246329 |
| NRP1 | neuropilin 1 | 0.0245101 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0244364 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0241866 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0237308 |
| GPC6 | glypican 6 | 0.023124 |
| CANX | calnexin | 0.0230462 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0229341 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0229012 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0225726 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0224566 |
| RASAL2 | RAS protein activator like 2 | 0.0220756 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0220233 |
| RNF213 | ring finger protein 213 | 0.0218482 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0217762 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0217343 |
| FNDC3A | fibronectin type III domain containing 3A | 0.021607 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0215944 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0215714 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0213485 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0212274 |
| ATXN1 | ataxin 1 | 0.0211432 |
| NTN4 | netrin 4 | 0.0210781 |
| INTS6 | integrator complex subunit 6 | 0.0208625 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0208281 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0207985 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0207441 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0203673 |
| VEGFC | vascular endothelial growth factor C | 0.0203657 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0202558 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0201417 |
| FLNA | filamin A, alpha | 0.0198777 |
| EGFR | epidermal growth factor receptor | 0.0198726 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0197255 |
| AHR | aryl hydrocarbon receptor | 0.0196652 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0195944 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.019427 |
| FHL2 | four and a half LIM domains 2 | 0.0193963 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0193811 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0193725 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0193412 |
| SYT1 | synaptotagmin I | 0.0191713 |
| MAP1B | microtubule-associated protein 1B | 0.0190544 |
| DUSP6 | dual specificity phosphatase 6 | 0.0188822 |
| OXR1 | oxidation resistance 1 | 0.0188559 |
| SFTPA2 | surfactant protein A2 | 0.018851 |
| OSMR | oncostatin M receptor | 0.0187664 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.018766 |
| GPATCH2L | G patch domain containing 2-like | 0.0187451 |
| EREG | epiregulin | 0.0185137 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0183346 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0178972 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0178069 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0172481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0393163 |
| PTMA | prothymosin, alpha | -0.038823 |
| FTL | ferritin, light polypeptide | -0.0369612 |
| VIM | vimentin | -0.0346431 |
| RPS6 | ribosomal protein S6 | -0.0319366 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0314852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310341 |
| TMSB10 | thymosin beta 10 | -0.0301982 |
| RNF145 | ring finger protein 145 | -0.029764 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.028654 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0275052 |
| CENPF | centromere protein F, 350/400kDa | -0.0263765 |
| RBM39 | RNA binding motif protein 39 | -0.0256181 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0246309 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243935 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0228673 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225938 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0223505 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0218424 |
| WDR45B | WD repeat domain 45B | -0.0199349 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0196915 |
| NUP58 | nucleoporin 58 | -0.0189344 |
| SEPTIN7 | septin 7 | -0.0188405 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0187166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0179673 |
| RPLP1 | ribosomal protein, large, P1 | -0.0179278 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0178482 |
| ZNF292 | zinc finger protein 292 | -0.01781 |
| TFG | TRK-fused gene | -0.0176255 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0170669 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0168332 |
| TXNRD1 | thioredoxin reductase 1 | -0.0158311 |
| XPO1 | exportin 1 | -0.0151686 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0151292 |
| RPL12 | ribosomal protein L12 | -0.0151288 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0148744 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0147965 |
| PCBP2 | poly(rC) binding protein 2 | -0.0146033 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0144261 |
| RPS19 | ribosomal protein S19 | -0.0142024 |
| ANLN | anillin, actin binding protein | -0.0141213 |
| RTN4 | reticulon 4 | -0.0140912 |
| CCNL1 | cyclin L1 | -0.0139712 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0138749 |
| NOP58 | NOP58 ribonucleoprotein | -0.0137496 |
| OGA | O-GlcNAcase | -0.0136629 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0134109 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0132137 |
| RHEB | Ras homolog enriched in brain | -0.0130941 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0130882 |
| RBM25 | RNA binding motif protein 25 | -0.0130304 |
| NEK7 | NIMA-related kinase 7 | -0.0129709 |
| WDR43 | WD repeat domain 43 | -0.0129478 |
| MATR3 | matrin 3 | -0.0129083 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0128833 |
| RLF | rearranged L-myc fusion | -0.0128521 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0127101 |
| CDC27 | cell division cycle 27 | -0.0126464 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0125709 |
| GOLGA4 | golgin A4 | -0.0125672 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0123255 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0122912 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.012194 |
| RAB6A | RAB6A, member RAS oncogene family | -0.012154 |
| RPL23 | ribosomal protein L23 | -0.0121397 |
| HMGA1 | high mobility group AT-hook 1 | -0.0121347 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0121319 |
| S100A6 | S100 calcium binding protein A6 | -0.0119716 |
| DIAPH3 | diaphanous-related formin 3 | -0.0119324 |
| RPLP0 | ribosomal protein, large, P0 | -0.0119283 |
| ECT2 | epithelial cell transforming 2 | -0.0118497 |
| RNF24 | ring finger protein 24 | -0.0118238 |
| YBX1 | Y box binding protein 1 | -0.0117807 |
| PFN1 | profilin 1 | -0.0117264 |
| LDHA | lactate dehydrogenase A | -0.0116769 |
| WAC | WW domain containing adaptor with coiled-coil | -0.011652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0114643 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0114571 |
| TPX2 | TPX2, microtubule-associated | -0.0114544 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0114449 |
| RIOK3 | RIO kinase 3 | -0.011418 |
| RPL9 | ribosomal protein L9 | -0.0114155 |
| RPS16 | ribosomal protein S16 | -0.0112987 |
| RPS24 | ribosomal protein S24 | -0.011176 |
| TPD52 | tumor protein D52 | -0.0109309 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.010926 |
| RPS23 | ribosomal protein S23 | -0.0108507 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0108043 |
| RPL8 | ribosomal protein L8 | -0.0107685 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0107426 |
| RPS25 | ribosomal protein S25 | -0.0107207 |
| HMGB3 | high mobility group box 3 | -0.0106707 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0106527 |
| RPL35A | ribosomal protein L35a | -0.0106493 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.010516 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0104103 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.010246 |
| QKI | QKI, KH domain containing, RNA binding | -0.0100359 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0100259 |
| RPS20 | ribosomal protein S20 | -0.00989227 |
