| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.11068 |
| CSTB | cystatin B (stefin B) | 0.107549 |
| VIM | vimentin | 0.105249 |
| MT2A | metallothionein 2A | 0.0984262 |
| TMSB10 | thymosin beta 10 | 0.0754251 |
| B2M | beta-2-microglobulin | 0.0733831 |
| SQSTM1 | sequestosome 1 | 0.0590068 |
| UBC | ubiquitin C | 0.057091 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0563855 |
| S100A6 | S100 calcium binding protein A6 | 0.0482076 |
| PTMA | prothymosin, alpha | 0.0434401 |
| ADM | adrenomedullin | 0.0398293 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.039022 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0382672 |
| FTL | ferritin, light polypeptide | 0.0367248 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0364739 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0349682 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0345958 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0343676 |
| STC1 | stanniocalcin 1 | 0.0337243 |
| ANXA2 | annexin A2 | 0.0307468 |
| RPL23 | ribosomal protein L23 | 0.030124 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0301144 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.029677 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0291561 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0287533 |
| GOLGA4 | golgin A4 | 0.0284996 |
| MYADM | myeloid-associated differentiation marker | 0.0283961 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0281117 |
| S100A10 | S100 calcium binding protein A10 | 0.028109 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0275501 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0272504 |
| LMNA | lamin A/C | 0.0269272 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0268332 |
| MT1X | metallothionein 1X | 0.0267642 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0267418 |
| RND3 | Rho family GTPase 3 | 0.026438 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0260582 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0259751 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0250586 |
| CLU | clusterin | 0.0243465 |
| HLA-E | major histocompatibility complex, class I, E | 0.024202 |
| RPS3 | ribosomal protein S3 | 0.0241102 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0239037 |
| HIP1 | huntingtin interacting protein 1 | 0.0219661 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0218221 |
| OPTN | optineurin | 0.0214999 |
| RPL12 | ribosomal protein L12 | 0.0213549 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0210155 |
| KLF6 | Kruppel-like factor 6 | 0.02084 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0208165 |
| INSIG2 | insulin induced gene 2 | 0.020069 |
| RPS8 | ribosomal protein S8 | 0.0195271 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0193796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.019378 |
| OGA | O-GlcNAcase | 0.0193106 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.019286 |
| RAB1A | RAB1A, member RAS oncogene family | 0.019231 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.019231 |
| CANX | calnexin | 0.0189785 |
| RPL26 | ribosomal protein L26 | 0.0188958 |
| ARRDC3 | arrestin domain containing 3 | 0.0187 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0186351 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0185855 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0181081 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0180242 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0179571 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0176789 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0175034 |
| FAM107B | family with sequence similarity 107, member B | 0.0174448 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0174198 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0174119 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0172517 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0172208 |
| RPL35 | ribosomal protein L35 | 0.0169115 |
| FNBP4 | formin binding protein 4 | 0.0168432 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0168102 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0163759 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0162817 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0162362 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0161325 |
| RACK1 | receptor for activated C kinase 1 | 0.0161027 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0159535 |
| RPS19 | ribosomal protein S19 | 0.0159225 |
| RAB10 | RAB10, member RAS oncogene family | 0.0158432 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0155561 |
| RPL34 | ribosomal protein L34 | 0.0155544 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0154942 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0154457 |
| FAM162A | family with sequence similarity 162, member A | 0.0154148 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0153363 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0152975 |
| RPL32 | ribosomal protein L32 | 0.0152492 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0152093 |
| RPLP1 | ribosomal protein, large, P1 | 0.0151798 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0150738 |
| ITSN2 | intersectin 2 | 0.0150482 |
| RLF | rearranged L-myc fusion | 0.0150435 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0150215 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0149857 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | -0.154967 |
| NAV1 | neuron navigator 1 | -0.142378 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.135936 |
| COL5A1 | collagen, type V, alpha 1 | -0.110647 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.095358 |
| CDH13 | cadherin 13 | -0.0774378 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0744991 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0708623 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0684114 |
| CD44 | CD44 molecule (Indian blood group) | -0.0649776 |
| AHNAK | AHNAK nucleoprotein | -0.0636092 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0616295 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0531054 |
| MAP1B | microtubule-associated protein 1B | -0.0504347 |
| THBS2 | thrombospondin 2 | -0.049739 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0474451 |
| EGFR | epidermal growth factor receptor | -0.0424651 |
| LOXL2 | lysyl oxidase-like 2 | -0.0415206 |
| RUNX1 | runt-related transcription factor 1 | -0.0412294 |
| FLNA | filamin A, alpha | -0.0366072 |
| GLIS3 | GLIS family zinc finger 3 | -0.034243 |
| FRMD4A | FERM domain containing 4A | -0.0325073 |
| MEIS2 | Meis homeobox 2 | -0.032109 |
| FN1 | fibronectin 1 | -0.0319991 |
| SEPTIN9 | septin 9 | -0.0319918 |
| MX2 | MX dynamin-like GTPase 2 | -0.0319571 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0313667 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0312892 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0309152 |
| PLAT | plasminogen activator, tissue | -0.0303142 |
| FSTL1 | follistatin-like 1 | -0.0300252 |
| EFNA5 | ephrin-A5 | -0.0295218 |
| FBN1 | fibrillin 1 | -0.0294752 |
| SUCNR1 | succinate receptor 1 | -0.028827 |
| POTEF | POTE ankyrin domain family, member F | -0.0281549 |
| COL5A2 | collagen, type V, alpha 2 | -0.0280576 |
| RNF213 | ring finger protein 213 | -0.0277436 |
| TPM1 | tropomyosin 1 (alpha) | -0.0275458 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0271967 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0268091 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0264737 |
| RRM2 | ribonucleotide reductase M2 | -0.0262478 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0256859 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0249452 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0249191 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0246212 |
| CUX1 | cut-like homeobox 1 | -0.024284 |
| SP3 | Sp3 transcription factor | -0.024053 |
| PRSS23 | protease, serine, 23 | -0.0236323 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235355 |
| FLNB | filamin B, beta | -0.0234181 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0233671 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0231711 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0229797 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.022926 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0227636 |
| COL3A1 | collagen, type III, alpha 1 | -0.0225876 |
| CDK6 | cyclin-dependent kinase 6 | -0.0224258 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0217401 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0213365 |
| RIGI | RNA sensor RIG-I | -0.0211584 |
| TNS3 | tensin 3 | -0.021153 |
| PLEC | plectin | -0.0210877 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0210423 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0209454 |
| CCND1 | cyclin D1 | -0.0206528 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0204123 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0203615 |
| ACTN4 | actinin, alpha 4 | -0.0203038 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0201259 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0200219 |
| OSMR | oncostatin M receptor | -0.0199822 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0197567 |
| PLXNA2 | plexin A2 | -0.0195282 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0194858 |
| SMYD3 | SET and MYND domain containing 3 | -0.0193803 |
| ZNF217 | zinc finger protein 217 | -0.0192702 |
| PXDN | peroxidasin | -0.0190955 |
| TENM3 | teneurin transmembrane protein 3 | -0.0189607 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0189133 |
| GSE1 | Gse1 coiled-coil protein | -0.0188783 |
| L1CAM | L1 cell adhesion molecule | -0.0186181 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0184306 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0183185 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0181288 |
| RAI14 | retinoic acid induced 14 | -0.0180955 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0180567 |
| KIAA1549L | KIAA1549-like | -0.0180185 |
| C1D | C1D nuclear receptor corepressor | -0.0179912 |
| DCLK2 | doublecortin-like kinase 2 | -0.0178234 |
| VEGFC | vascular endothelial growth factor C | -0.017595 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0174847 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0173259 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0172239 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0171114 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.01708 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0167734 |
| PARD3 | par-3 family cell polarity regulator | -0.0166852 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0166095 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0164482 |
