| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | 0.155372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0917781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0743454 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0690865 |
| PTMA | prothymosin, alpha | 0.0686933 |
| MGP | matrix Gla protein | 0.0545235 |
| CANX | calnexin | 0.0510042 |
| VIM | vimentin | 0.0503916 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.048141 |
| HMGA2 | high mobility group AT-hook 2 | 0.0439444 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0435113 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0422587 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0410773 |
| ENO1 | enolase 1, (alpha) | 0.0381135 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0373551 |
| RPS8 | ribosomal protein S8 | 0.0364872 |
| ADIPOR2 | adiponectin receptor 2 | 0.0361516 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0353686 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0351879 |
| GOLGA4 | golgin A4 | 0.0350674 |
| CDK6 | cyclin-dependent kinase 6 | 0.0338172 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0328503 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.032404 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0309576 |
| ASPH | aspartate beta-hydroxylase | 0.0296573 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0294077 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0290464 |
| RPL37A | ribosomal protein L37a | 0.0287369 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0278539 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0278465 |
| FMNL2 | formin-like 2 | 0.0274577 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.027227 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0268333 |
| TRIM9 | tripartite motif containing 9 | 0.0265897 |
| FTL | ferritin, light polypeptide | 0.0265587 |
| KIF5B | kinesin family member 5B | 0.0261296 |
| CALD1 | caldesmon 1 | 0.0259192 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0258325 |
| PKM | pyruvate kinase, muscle | 0.0254227 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025322 |
| SEPTIN11 | septin 11 | 0.0250333 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0248061 |
| RPL10A | ribosomal protein L10a | 0.024658 |
| RPL31 | ribosomal protein L31 | 0.0245768 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0243267 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.024081 |
| MYOF | myoferlin | 0.0238097 |
| RPS13 | ribosomal protein S13 | 0.0237913 |
| ATXN2 | ataxin 2 | 0.0232772 |
| KAZN | kazrin, periplakin interacting protein | 0.0230443 |
| SNX14 | sorting nexin 14 | 0.0228694 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0225565 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0221622 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0219622 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0218047 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0216622 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0214828 |
| SCFD2 | sec1 family domain containing 2 | 0.0214775 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0213991 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0213977 |
| SPPL3 | signal peptide peptidase like 3 | 0.0213648 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0213475 |
| LOXL2 | lysyl oxidase-like 2 | 0.0210835 |
| RPLP1 | ribosomal protein, large, P1 | 0.0210119 |
| NDRG1 | N-myc downstream regulated 1 | 0.0208252 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0207294 |
| SET | SET nuclear proto-oncogene | 0.0207244 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0206925 |
| CALU | calumenin | 0.0206771 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.020354 |
| SIK3 | SIK family kinase 3 | 0.0203419 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0203351 |
| COL5A2 | collagen, type V, alpha 2 | 0.0201482 |
| COPA | coatomer protein complex, subunit alpha | 0.0201403 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0200326 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0200189 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0199865 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0199246 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0198152 |
| USP15 | ubiquitin specific peptidase 15 | 0.0197633 |
| TMF1 | TATA element modulatory factor 1 | 0.0195134 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0194287 |
| IPO7 | importin 7 | 0.0193921 |
| FBXO11 | F-box protein 11 | 0.0193482 |
| PLS3 | plastin 3 | 0.0192885 |
| CTBP2 | C-terminal binding protein 2 | 0.0192763 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0192754 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.019096 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0189759 |
| RTN4 | reticulon 4 | 0.0188014 |
| RPS23 | ribosomal protein S23 | 0.0187791 |
| WDR26 | WD repeat domain 26 | 0.0187519 |
| RPS3 | ribosomal protein S3 | 0.0187294 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0186876 |
| TPI1 | triosephosphate isomerase 1 | 0.0186763 |
| RPS25 | ribosomal protein S25 | 0.0185896 |
| WDR43 | WD repeat domain 43 | 0.0184642 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0183711 |
| SERTAD2 | SERTA domain containing 2 | 0.018292 |
| TMSB10 | thymosin beta 10 | 0.0182182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.155319 |
| MEST | mesoderm specific transcript | -0.103672 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0594729 |
| GSE1 | Gse1 coiled-coil protein | -0.0555501 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0544861 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0541737 |
| PRELID2 | PRELI domain containing 2 | -0.0501733 |
| ITGAV | integrin, alpha V | -0.0438317 |
| CENPF | centromere protein F, 350/400kDa | -0.0410339 |
| DIAPH3 | diaphanous-related formin 3 | -0.0393032 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0387135 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0364696 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0360193 |
| MKI67 | marker of proliferation Ki-67 | -0.0320722 |
| NFIA | nuclear factor I/A | -0.0318811 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0315738 |
| BCOR | BCL6 corepressor | -0.0310171 |
| HOXA3 | homeobox A3 | -0.0305781 |
| TUBB | tubulin, beta class I | -0.0303561 |
| ATG10 | autophagy related 10 | -0.0298069 |
| RAD51B | RAD51 paralog B | -0.0297869 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0295525 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292066 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0282048 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0275941 |
| PDE10A | phosphodiesterase 10A | -0.027501 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0272238 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0271279 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0271223 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0266148 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0266086 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0264721 |
| WWOX | WW domain containing oxidoreductase | -0.0263916 |
| FNIP1 | folliculin interacting protein 1 | -0.026235 |
| HELLS | helicase, lymphoid-specific | -0.0260937 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0256073 |
| ATXN10 | ataxin 10 | -0.0253695 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.0245257 |
| AOPEP | aminopeptidase O (putative) | -0.0242218 |
| NCOR1 | nuclear receptor corepressor 1 | -0.023817 |
| TCF12 | transcription factor 12 | -0.0235575 |
| EXOC4 | exocyst complex component 4 | -0.0234034 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0231832 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0230533 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0227836 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0225589 |
| ZNF516 | zinc finger protein 516 | -0.0225179 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0224553 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0222516 |
| TTK | TTK protein kinase | -0.0221478 |
| USP22 | ubiquitin specific peptidase 22 | -0.0220087 |
| SMC3 | structural maintenance of chromosomes 3 | -0.022002 |
| ZNF292 | zinc finger protein 292 | -0.0219296 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0217607 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0217387 |
| PHF21A | PHD finger protein 21A | -0.0213751 |
| ZNF736 | zinc finger protein 736 | -0.0213316 |
| DOCK3 | dedicator of cytokinesis 3 | -0.021246 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0209543 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0209326 |
| KIF18B | kinesin family member 18B | -0.0205505 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0203336 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0202018 |
| PDGFC | platelet derived growth factor C | -0.0201691 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0201289 |
| KIF11 | kinesin family member 11 | -0.0201175 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0200575 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0199076 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0198907 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0197407 |
| OGA | O-GlcNAcase | -0.0196353 |
| RNF216 | ring finger protein 216 | -0.019607 |
| SGCE | sarcoglycan, epsilon | -0.019596 |
| CEP192 | centrosomal protein 192kDa | -0.0195807 |
| TAPBP | TAP binding protein (tapasin) | -0.0195449 |
| NFIB | nuclear factor I/B | -0.0195314 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0191837 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.019021 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0189731 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0188787 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0188258 |
| KIF18A | kinesin family member 18A | -0.018762 |
| SF1 | splicing factor 1 | -0.0187001 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0186131 |
| OLA1 | Obg-like ATPase 1 | -0.0183696 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0183454 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0183179 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0183008 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0181167 |
| SQSTM1 | sequestosome 1 | -0.0179593 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.01772 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0176845 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0175595 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0175384 |
| AASS | aminoadipate-semialdehyde synthase | -0.0175355 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0175276 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0175166 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.017478 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0174457 |
| ECT2 | epithelial cell transforming 2 | -0.0174013 |
