| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Loperamide (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0589033 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0306222 |
| GOLGA4 | golgin A4 | 0.0281282 |
| NUP58 | nucleoporin 58 | 0.0275876 |
| LDHA | lactate dehydrogenase A | 0.027034 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0269109 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0263843 |
| RNF145 | ring finger protein 145 | 0.02508 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0247508 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0222837 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0219372 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0218264 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0212192 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0190492 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0185394 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0173528 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0171381 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0170062 |
| SRP54 | signal recognition particle 54kDa | 0.0169049 |
| FAM162A | family with sequence similarity 162, member A | 0.016273 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0162445 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0160593 |
| DSTN | destrin (actin depolymerizing factor) | 0.0159648 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0156368 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0154572 |
| SQLE | squalene epoxidase | 0.0153547 |
| MLEC | malectin | 0.0153173 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0151702 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0148514 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0146233 |
| CCNY | cyclin Y | 0.0146151 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0144687 |
| HELZ | helicase with zinc finger | 0.0142515 |
| USP3 | ubiquitin specific peptidase 3 | 0.0141411 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0137563 |
| PDS5B | PDS5 cohesin associated factor B | 0.0137185 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0136392 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0135801 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0134219 |
| KIF5B | kinesin family member 5B | 0.0134174 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0133875 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0130604 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.012976 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0128562 |
| RPS2 | ribosomal protein S2 | 0.0127427 |
| VEGFA | vascular endothelial growth factor A | 0.012389 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0123504 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0121923 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0121659 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0121519 |
| XPO1 | exportin 1 | 0.0121095 |
| ENO1 | enolase 1, (alpha) | 0.0119488 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0118047 |
| MEMO1 | mediator of cell motility 1 | 0.011751 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0117312 |
| RPS7 | ribosomal protein S7 | 0.0117015 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0116859 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0116163 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.011575 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0114744 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0114639 |
| TMEM65 | transmembrane protein 65 | 0.0114024 |
| PGK1 | phosphoglycerate kinase 1 | 0.0113684 |
| TPD52 | tumor protein D52 | 0.0113556 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0113374 |
| NUB1 | negative regulator of ubiquitin-like proteins 1 | 0.0111595 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0111545 |
| SPAG9 | sperm associated antigen 9 | 0.0110829 |
| CA12 | carbonic anhydrase XII | 0.0109425 |
| KRT19 | keratin 19, type I | 0.0108778 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0108555 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0108052 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0106678 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0106572 |
| RLF | rearranged L-myc fusion | 0.0106208 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0106169 |
| PDE8A | phosphodiesterase 8A | 0.0105384 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0103292 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0101161 |
| WDR45B | WD repeat domain 45B | 0.0100966 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0100298 |
| HMGB2 | high mobility group box 2 | 0.00996502 |
| CSTB | cystatin B (stefin B) | 0.00986215 |
| BBX | bobby sox homolog (Drosophila) | 0.00983507 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.00982009 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00980129 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00978104 |
| S100A6 | S100 calcium binding protein A6 | 0.00975801 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.00969791 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00963901 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.00953956 |
| RTN3 | reticulon 3 | 0.00952437 |
| RPL10A | ribosomal protein L10a | 0.0094831 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00948068 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.00947475 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.00945066 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00941793 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00934879 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00928966 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0092554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.141696 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0970794 |
| ACTN4 | actinin, alpha 4 | -0.0902705 |
| LMO7 | LIM domain 7 | -0.0772024 |
| AHNAK | AHNAK nucleoprotein | -0.0742197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0734333 |
| UBC | ubiquitin C | -0.0699951 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0664045 |
| EZR | ezrin | -0.0648451 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0632455 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0588703 |
| ATXN1 | ataxin 1 | -0.0570991 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.057063 |
| ACTG1 | actin gamma 1 | -0.0566893 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0522634 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0506387 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.048109 |
| KRT8 | keratin 8, type II | -0.0472067 |
| VCL | vinculin | -0.0456664 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0455054 |
| SMAD3 | SMAD family member 3 | -0.0438779 |
| TMSB10 | thymosin beta 10 | -0.0430923 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0429351 |
| MYO1E | myosin IE | -0.0423859 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0420929 |
| STK24 | serine/threonine kinase 24 | -0.0416133 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0408502 |
| DST | dystonin | -0.0399448 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0381731 |
| TJP1 | tight junction protein 1 | -0.0365068 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0364472 |
| BCL2L1 | BCL2-like 1 | -0.0363365 |
| WWC1 | WW and C2 domain containing 1 | -0.036109 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0360801 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0356209 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0355615 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0353373 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350188 |
| EGR1 | early growth response 1 | -0.0342588 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0337245 |
| PDZD8 | PDZ domain containing 8 | -0.0334804 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0334323 |
| RPS27A | ribosomal protein S27a | -0.0330647 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0328545 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0327708 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0324209 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0321581 |
| ETV6 | ets variant 6 | -0.0321049 |
| RBM39 | RNA binding motif protein 39 | -0.0319464 |
| JUN | jun proto-oncogene | -0.0318795 |
| AREG | amphiregulin | -0.0314688 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0311 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0310569 |
| TRIB1 | tribbles pseudokinase 1 | -0.0303986 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0303388 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0296961 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0295518 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0295197 |
| FAT1 | FAT atypical cadherin 1 | -0.029294 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0291 |
| HDLBP | high density lipoprotein binding protein | -0.028982 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0285391 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0283819 |
| EXPH5 | exophilin 5 | -0.0282253 |
| RPS24 | ribosomal protein S24 | -0.0281154 |
| SEPTIN9 | septin 9 | -0.0279921 |
| RPS11 | ribosomal protein S11 | -0.027613 |
| PTMA | prothymosin, alpha | -0.0272098 |
| SMYD3 | SET and MYND domain containing 3 | -0.0271776 |
| FHL2 | four and a half LIM domains 2 | -0.0268152 |
| TMC5 | transmembrane channel-like 5 | -0.0267103 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0265913 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0263785 |
| MCL1 | myeloid cell leukemia 1 | -0.0260945 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.026068 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260613 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0254612 |
| VMP1 | vacuole membrane protein 1 | -0.0252121 |
| LMNA | lamin A/C | -0.0247147 |
| LATS2 | large tumor suppressor kinase 2 | -0.0241898 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0241212 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0240019 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0239794 |
| MYO1D | myosin ID | -0.0233448 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0232992 |
| RPL5 | ribosomal protein L5 | -0.0231714 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230791 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0230514 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0229986 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0229025 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0228243 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0222676 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0219071 |
| RPL9 | ribosomal protein L9 | -0.0219056 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0218075 |
| LAMB3 | laminin, beta 3 | -0.0217934 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0217111 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0216986 |
| NUP98 | nucleoporin 98kDa | -0.0215625 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0215319 |
