| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.100064 |
| NPSR1 | neuropeptide S receptor 1 | 0.0955904 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0889289 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0863565 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0853706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0800773 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0779654 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0580121 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0573647 |
| HYOU1 | hypoxia up-regulated 1 | 0.0514368 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0482504 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0478566 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0462512 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0448181 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0406947 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0406799 |
| KLHL29 | kelch-like family member 29 | 0.0404433 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0404225 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0394306 |
| TES | testin LIM domain protein | 0.0378717 |
| CANX | calnexin | 0.037618 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0367852 |
| FAM13A | family with sequence similarity 13, member A | 0.0355809 |
| VEGFA | vascular endothelial growth factor A | 0.0353057 |
| TMF1 | TATA element modulatory factor 1 | 0.0348812 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0340114 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0326793 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0326287 |
| HM13 | histocompatibility (minor) 13 | 0.0325997 |
| DSTN | destrin (actin depolymerizing factor) | 0.032051 |
| SET | SET nuclear proto-oncogene | 0.0314005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313948 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0308651 |
| SRP54 | signal recognition particle 54kDa | 0.0303316 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0301094 |
| CDK13 | cyclin-dependent kinase 13 | 0.0299958 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0290022 |
| COG5 | component of oligomeric golgi complex 5 | 0.0282109 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0279769 |
| GOLGB1 | golgin B1 | 0.0273131 |
| ENO1 | enolase 1, (alpha) | 0.0272722 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0264541 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.02628 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0262604 |
| HKDC1 | hexokinase domain containing 1 | 0.0255138 |
| SETD5 | SET domain containing 5 | 0.0254419 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0253997 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0253142 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0253008 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0249315 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0246756 |
| CDK6 | cyclin-dependent kinase 6 | 0.0244608 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0242987 |
| PGM3 | phosphoglucomutase 3 | 0.0240024 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0238498 |
| ATXN1 | ataxin 1 | 0.0238147 |
| NUP58 | nucleoporin 58 | 0.0235413 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0234222 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0232816 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0231383 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0230723 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0228152 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0226334 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.022407 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0220672 |
| SCFD1 | sec1 family domain containing 1 | 0.0220085 |
| VMP1 | vacuole membrane protein 1 | 0.021969 |
| ITGA6 | integrin, alpha 6 | 0.0218929 |
| MLEC | malectin | 0.0218624 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0218149 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0217973 |
| TPM3 | tropomyosin 3 | 0.0217245 |
| EHBP1 | EH domain binding protein 1 | 0.021677 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.021578 |
| ANXA3 | annexin A3 | 0.0212968 |
| HELZ | helicase with zinc finger | 0.021223 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0211138 |
| TRAM1 | translocation associated membrane protein 1 | 0.0209755 |
| KIF16B | kinesin family member 16B | 0.0209205 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0209057 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0205368 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0204022 |
| PHF3 | PHD finger protein 3 | 0.020278 |
| MYO5B | myosin VB | 0.0201206 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0198436 |
| FNIP1 | folliculin interacting protein 1 | 0.0195376 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0194496 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0193758 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0193482 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0193479 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0193369 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0193256 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0193226 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0192364 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0190251 |
| PMM2 | phosphomannomutase 2 | 0.0189496 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0188737 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0188397 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0185612 |
| RPS7 | ribosomal protein S7 | 0.0185602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.179982 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154628 |
| EMP1 | epithelial membrane protein 1 | -0.0990287 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.085216 |
| RPL35A | ribosomal protein L35a | -0.0717567 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.069354 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0690005 |
| TMC5 | transmembrane channel-like 5 | -0.0682925 |
| B2M | beta-2-microglobulin | -0.066635 |
| S100A10 | S100 calcium binding protein A10 | -0.0642483 |
| RPS19 | ribosomal protein S19 | -0.0642365 |
| RPLP1 | ribosomal protein, large, P1 | -0.0632821 |
| ACTN4 | actinin, alpha 4 | -0.0560721 |
| FTL | ferritin, light polypeptide | -0.0526871 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0520602 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0503327 |
| RRBP1 | ribosome binding protein 1 | -0.0490875 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0459867 |
| H1-0 | H1.0 linker histone | -0.0459551 |
| RPS21 | ribosomal protein S21 | -0.0454185 |
| S100A9 | S100 calcium binding protein A9 | -0.0451812 |
| EPCAM | epithelial cell adhesion molecule | -0.0442512 |
| EZR | ezrin | -0.0441013 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0416142 |
| S100P | S100 calcium binding protein P | -0.0416008 |
| ATF5 | activating transcription factor 5 | -0.0412296 |
| TXNRD1 | thioredoxin reductase 1 | -0.0404018 |
| HLA-E | major histocompatibility complex, class I, E | -0.038849 |
| ACTG1 | actin gamma 1 | -0.0386093 |
| CLDN4 | claudin 4 | -0.0384492 |
| RPL19 | ribosomal protein L19 | -0.0366149 |
| HLA-C | major histocompatibility complex, class I, C | -0.0352739 |
| KRT8 | keratin 8, type II | -0.0352112 |
| RPL23 | ribosomal protein L23 | -0.0350026 |
| RPL38 | ribosomal protein L38 | -0.0344023 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0341862 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0341647 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0340692 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0339447 |
| HLA-B | major histocompatibility complex, class I, B | -0.03388 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0335279 |
| PTMA | prothymosin, alpha | -0.0332919 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.033193 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.033097 |
| RPL28 | ribosomal protein L28 | -0.032988 |
| RPS24 | ribosomal protein S24 | -0.0327207 |
| KLF6 | Kruppel-like factor 6 | -0.0327062 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0323571 |
| HLA-A | major histocompatibility complex, class I, A | -0.0320276 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0318781 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0318023 |
| RPL12 | ribosomal protein L12 | -0.0310481 |
| TMEM45B | transmembrane protein 45B | -0.0302673 |
| H3-3B | H3.3 histone B | -0.0302387 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0302215 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0301296 |
| RPL34 | ribosomal protein L34 | -0.0286998 |
| RPL8 | ribosomal protein L8 | -0.0285199 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0284686 |
| RPL32 | ribosomal protein L32 | -0.0284234 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283458 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0282455 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0274592 |
| LMO7 | LIM domain 7 | -0.0274473 |
| RNF213 | ring finger protein 213 | -0.0274202 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0268657 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267357 |
| SEPTIN9 | septin 9 | -0.0267146 |
| RPL36 | ribosomal protein L36 | -0.0266727 |
| RPL35 | ribosomal protein L35 | -0.0266116 |
| KRT19 | keratin 19, type I | -0.0263838 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0260166 |
| MUC17 | mucin 17, cell surface associated | -0.0259723 |
| RPL26 | ribosomal protein L26 | -0.025967 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.025699 |
| ANXA2 | annexin A2 | -0.025443 |
| RPS29 | ribosomal protein S29 | -0.0250962 |
| RPL27 | ribosomal protein L27 | -0.0245985 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0240908 |
| LMNA | lamin A/C | -0.0240895 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240462 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0240416 |
| RPS15 | ribosomal protein S15 | -0.0238941 |
| PRSS3 | protease, serine, 3 | -0.0237989 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0236023 |
| JUP | junction plakoglobin | -0.0233884 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0232065 |
| RPS8 | ribosomal protein S8 | -0.0231358 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0229458 |
| RPL9 | ribosomal protein L9 | -0.0227501 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0226323 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0225365 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0224301 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0223227 |
| WWC1 | WW and C2 domain containing 1 | -0.0219772 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0217038 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0216262 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0214916 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0214258 |
| ITGB4 | integrin, beta 4 | -0.0212936 |
