| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.0724462 |
| RPS6 | ribosomal protein S6 | 0.0655739 |
| PTMA | prothymosin, alpha | 0.0581821 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0542861 |
| VIM | vimentin | 0.0525984 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0466721 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0417581 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370531 |
| RPL23 | ribosomal protein L23 | 0.0364295 |
| RPS8 | ribosomal protein S8 | 0.0350544 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0341531 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0329567 |
| RPL12 | ribosomal protein L12 | 0.0317419 |
| NUP58 | nucleoporin 58 | 0.0307937 |
| RPL21 | ribosomal protein L21 | 0.0307271 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0290734 |
| RPLP2 | ribosomal protein, large, P2 | 0.0288733 |
| RNF145 | ring finger protein 145 | 0.0276131 |
| RPS13 | ribosomal protein S13 | 0.0266845 |
| RLF | rearranged L-myc fusion | 0.025608 |
| RPL11 | ribosomal protein L11 | 0.0244058 |
| CSTB | cystatin B (stefin B) | 0.0239905 |
| MT2A | metallothionein 2A | 0.0237745 |
| SPAG9 | sperm associated antigen 9 | 0.0235285 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230207 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0228064 |
| RPL10A | ribosomal protein L10a | 0.0225796 |
| RPL36A | ribosomal protein L36a | 0.0217795 |
| RPS12 | ribosomal protein S12 | 0.0214095 |
| CENPF | centromere protein F, 350/400kDa | 0.0208082 |
| RPS19 | ribosomal protein S19 | 0.0205765 |
| QKI | QKI, KH domain containing, RNA binding | 0.020564 |
| RPS3 | ribosomal protein S3 | 0.0202939 |
| RPLP0 | ribosomal protein, large, P0 | 0.0189125 |
| RPL32 | ribosomal protein L32 | 0.0187389 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0187277 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0184237 |
| RYBP | RING1 and YY1 binding protein | 0.0183903 |
| RPS25 | ribosomal protein S25 | 0.0175356 |
| B2M | beta-2-microglobulin | 0.0174427 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0170932 |
| RPL31 | ribosomal protein L31 | 0.017039 |
| RPS23 | ribosomal protein S23 | 0.0170052 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0168053 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0164579 |
| GOLGA4 | golgin A4 | 0.0164281 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0156252 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0153248 |
| RPS29 | ribosomal protein S29 | 0.0150428 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.01496 |
| RPL35A | ribosomal protein L35a | 0.0148988 |
| RPS16 | ribosomal protein S16 | 0.014806 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0147582 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0146563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0146492 |
| RPS27 | ribosomal protein S27 | 0.014442 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0142886 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0142155 |
| RPL18 | ribosomal protein L18 | 0.0141123 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0140083 |
| YTHDC1 | YTH domain containing 1 | 0.0139891 |
| ADM | adrenomedullin | 0.0138778 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0138751 |
| TMEM87A | transmembrane protein 87A | 0.0138685 |
| RIOK3 | RIO kinase 3 | 0.0136729 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0136183 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0135974 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.013409 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0132618 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0132398 |
| RAB8B | RAB8B, member RAS oncogene family | 0.013224 |
| RPL19 | ribosomal protein L19 | 0.0131931 |
| RPL7 | ribosomal protein L7 | 0.013118 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0130815 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0130406 |
| RPL15 | ribosomal protein L15 | 0.0129851 |
| YBX3 | Y box binding protein 3 | 0.012761 |
| RPS17 | ribosomal protein S17 | 0.012675 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0124242 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0123976 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0123373 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0122524 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0122483 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0122408 |
| PLIN2 | perilipin 2 | 0.0122235 |
| SRP54 | signal recognition particle 54kDa | 0.0122152 |
| S100A10 | S100 calcium binding protein A10 | 0.0121325 |
| PHIP | pleckstrin homology domain interacting protein | 0.0121292 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0120202 |
| TMEM41B | transmembrane protein 41B | 0.0120106 |
| RPL26 | ribosomal protein L26 | 0.0119977 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0118477 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0118459 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0118386 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0118378 |
| TMF1 | TATA element modulatory factor 1 | 0.0118294 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0117404 |
| FAM162A | family with sequence similarity 162, member A | 0.0116809 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0116608 |
| CD109 | CD109 molecule | 0.0116454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146012 |
| EFNA5 | ephrin-A5 | -0.126149 |
| EXT1 | exostosin glycosyltransferase 1 | -0.121383 |
| AHNAK | AHNAK nucleoprotein | -0.0981963 |
| RUNX1 | runt-related transcription factor 1 | -0.0938829 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0831192 |
| ACTG1 | actin gamma 1 | -0.0807862 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0780943 |
| GPC6 | glypican 6 | -0.0742302 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0676064 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0673172 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.065381 |
| KIAA1549L | KIAA1549-like | -0.0594283 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0575473 |
| NTM | neurotrimin | -0.0574616 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0569451 |
| FLNA | filamin A, alpha | -0.0538945 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0510454 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0503703 |
| DTNA | dystrobrevin, alpha | -0.0493076 |
| ASPH | aspartate beta-hydroxylase | -0.0483893 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0478435 |
| PKM | pyruvate kinase, muscle | -0.0464973 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0462888 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0459433 |
| PRKCE | protein kinase C, epsilon | -0.0449756 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0447982 |
| LOC112694756 | uncharaterized LOC112694756 | -0.042582 |
| KIAA1217 | KIAA1217 | -0.0424964 |
| CD44 | CD44 molecule (Indian blood group) | -0.0415173 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0409383 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0404956 |
| SMAD3 | SMAD family member 3 | -0.0399173 |
| OSMR | oncostatin M receptor | -0.0379688 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0377702 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0377387 |
| PRRC2B | proline-rich coiled-coil 2B | -0.037578 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0365593 |
| MSR1 | macrophage scavenger receptor 1 | -0.0365357 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0357591 |
| CDK6 | cyclin-dependent kinase 6 | -0.0356951 |
| MMP12 | matrix metallopeptidase 12 | -0.0354979 |
| NAV1 | neuron navigator 1 | -0.0354822 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0345658 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0344362 |
| ANO6 | anoctamin 6 | -0.0338544 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0335064 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0334925 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0334445 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0334355 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.03325 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.032274 |
| CALD1 | caldesmon 1 | -0.0316743 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0316067 |
| PLEC | plectin | -0.0314801 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0312261 |
| VCL | vinculin | -0.0306974 |
| NDRG1 | N-myc downstream regulated 1 | -0.0306748 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299049 |
| DST | dystonin | -0.0296391 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.028724 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0285442 |
| FRMD6 | FERM domain containing 6 | -0.0279858 |
| ERBIN | erbb2 interacting protein | -0.0279809 |
| ZNF804A | zinc finger protein 804A | -0.027678 |
| SMYD3 | SET and MYND domain containing 3 | -0.0276157 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0275824 |
| ANXA2 | annexin A2 | -0.0268145 |
| FOXP1 | forkhead box P1 | -0.02667 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0266483 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.026602 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0264041 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0263671 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0263111 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0261017 |
| NABP1 | nucleic acid binding protein 1 | -0.0260714 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0259209 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0255114 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0253092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0252558 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0251742 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0251158 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0249141 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0246916 |
| KYNU | kynureninase | -0.0244282 |
| TXNRD1 | thioredoxin reductase 1 | -0.0243225 |
| MYO10 | myosin X | -0.0242649 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0242631 |
| PARD3 | par-3 family cell polarity regulator | -0.0241775 |
| APP | amyloid beta (A4) precursor protein | -0.0241297 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0239823 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0238801 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0238293 |
| RIGI | RNA sensor RIG-I | -0.0234373 |
| ACTN1 | actinin, alpha 1 | -0.0233809 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0232534 |
| FN1 | fibronectin 1 | -0.0232459 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0226582 |
| RNF213 | ring finger protein 213 | -0.0225563 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0222156 |
