| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Loperamide (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101832 |
| RPS2 | ribosomal protein S2 | 0.0941612 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0906629 |
| TXNIP | thioredoxin interacting protein | 0.0749843 |
| DSPP | dentin sialophosphoprotein | 0.0741152 |
| AREG | amphiregulin | 0.069778 |
| GOLGA4 | golgin A4 | 0.0661289 |
| VEGFA | vascular endothelial growth factor A | 0.061226 |
| RPS6 | ribosomal protein S6 | 0.0597814 |
| RPS12 | ribosomal protein S12 | 0.0543273 |
| EREG | epiregulin | 0.0508125 |
| RNF145 | ring finger protein 145 | 0.0481473 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0477054 |
| KIF5B | kinesin family member 5B | 0.046611 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0458339 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0455952 |
| LMO7 | LIM domain 7 | 0.0418742 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0407305 |
| WAC | WW domain containing adaptor with coiled-coil | 0.039866 |
| RPL7 | ribosomal protein L7 | 0.0385015 |
| TMF1 | TATA element modulatory factor 1 | 0.0377403 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0373592 |
| RPL21 | ribosomal protein L21 | 0.0370247 |
| FAM13A | family with sequence similarity 13, member A | 0.0364744 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0362813 |
| RBM39 | RNA binding motif protein 39 | 0.0351192 |
| RPL3 | ribosomal protein L3 | 0.03356 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0334251 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0330556 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0322284 |
| PTMA | prothymosin, alpha | 0.0319278 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.031675 |
| RPS3 | ribosomal protein S3 | 0.0311833 |
| RPL26 | ribosomal protein L26 | 0.0311344 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0308161 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0307526 |
| TPR | translocated promoter region, nuclear basket protein | 0.030332 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0297614 |
| PDZD8 | PDZ domain containing 8 | 0.0295751 |
| RPL12 | ribosomal protein L12 | 0.0294162 |
| RPS8 | ribosomal protein S8 | 0.0289204 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0288391 |
| PNN | pinin, desmosome associated protein | 0.0287499 |
| XPO1 | exportin 1 | 0.028529 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.028324 |
| RPL11 | ribosomal protein L11 | 0.0282633 |
| SETD5 | SET domain containing 5 | 0.0282441 |
| SET | SET nuclear proto-oncogene | 0.0280892 |
| B2M | beta-2-microglobulin | 0.0279631 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0279368 |
| TPM3 | tropomyosin 3 | 0.0273524 |
| BRD2 | bromodomain containing 2 | 0.0272511 |
| HELZ | helicase with zinc finger | 0.027005 |
| RPL37A | ribosomal protein L37a | 0.0269537 |
| RPL18 | ribosomal protein L18 | 0.0269363 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0262873 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0261513 |
| NCKAP1 | NCK-associated protein 1 | 0.0257533 |
| RPL36 | ribosomal protein L36 | 0.0257532 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.025477 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0252784 |
| RPL23 | ribosomal protein L23 | 0.0248679 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0246559 |
| PAPOLA | poly(A) polymerase alpha | 0.0245811 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0242347 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0242195 |
| SPAG9 | sperm associated antigen 9 | 0.0241845 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0240522 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0239494 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0237768 |
| YTHDC1 | YTH domain containing 1 | 0.0236298 |
| VMP1 | vacuole membrane protein 1 | 0.0235789 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0235744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0235313 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0234681 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0234404 |
| PCM1 | pericentriolar material 1 | 0.0233013 |
| ATF4 | activating transcription factor 4 | 0.0232971 |
| EZR | ezrin | 0.0231805 |
| NUP58 | nucleoporin 58 | 0.0231223 |
| SUCO | SUN domain containing ossification factor | 0.0230844 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0230316 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.022983 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0229099 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0229089 |
| ZNF292 | zinc finger protein 292 | 0.0227793 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0225499 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0224885 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0222725 |
| NEK7 | NIMA-related kinase 7 | 0.0221739 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0220839 |
| ASPH | aspartate beta-hydroxylase | 0.021844 |
| MED13L | mediator complex subunit 13-like | 0.0218344 |
| RPS27 | ribosomal protein S27 | 0.0217785 |
| PLS1 | plastin 1 | 0.0216553 |
| GOLGB1 | golgin B1 | 0.0213712 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0208004 |
| RPS18 | ribosomal protein S18 | 0.0207731 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0207627 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.18901 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.110231 |
| TMSB10 | thymosin beta 10 | -0.106352 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0912624 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0827185 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0823937 |
| ACTN4 | actinin, alpha 4 | -0.0799189 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0725267 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0662774 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0633534 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0630432 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0627264 |
| ONECUT3 | one cut homeobox 3 | -0.0617999 |
| AHNAK | AHNAK nucleoprotein | -0.0615099 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.060283 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0593612 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0586311 |
| VCL | vinculin | -0.057264 |
| FAT1 | FAT atypical cadherin 1 | -0.0568303 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0560341 |
| GPHN | gephyrin | -0.0533867 |
| FLNB | filamin B, beta | -0.052831 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0526594 |
| ANXA2 | annexin A2 | -0.0524847 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0522024 |
| KRT8 | keratin 8, type II | -0.0504017 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0501897 |
| FHIT | fragile histidine triad | -0.046227 |
| TNS4 | tensin 4 | -0.0442939 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.044222 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433575 |
| ACTG1 | actin gamma 1 | -0.0414899 |
| H1-0 | H1.0 linker histone | -0.0410684 |
| MUC17 | mucin 17, cell surface associated | -0.0409398 |
| ITGB4 | integrin, beta 4 | -0.0401184 |
| CADPS | Ca++-dependent secretion activator | -0.0393043 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0382028 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0372146 |
| CALB1 | calbindin 1, 28kDa | -0.0367109 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0365433 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0352653 |
| LAMA4 | laminin, alpha 4 | -0.034207 |
| CCND1 | cyclin D1 | -0.0340038 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0338141 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.03332 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0330096 |
| FOXP1 | forkhead box P1 | -0.0329382 |
| HMGA1 | high mobility group AT-hook 1 | -0.0327256 |
| MSI2 | musashi RNA-binding protein 2 | -0.03206 |
| PIGR | polymeric immunoglobulin receptor | -0.0313972 |
| EHBP1 | EH domain binding protein 1 | -0.0311246 |
| DIAPH2 | diaphanous-related formin 2 | -0.0306956 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0300649 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0299896 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0286855 |
| HMGB1 | high mobility group box 1 | -0.0281527 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0280798 |
| SMYD3 | SET and MYND domain containing 3 | -0.0279541 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0279498 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0275423 |
| POF1B | premature ovarian failure, 1B | -0.0274556 |
| RAD51B | RAD51 paralog B | -0.0272077 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0271189 |
| DENND1A | DENN/MADD domain containing 1A | -0.0268115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026519 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0264788 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0262951 |
| RPS24 | ribosomal protein S24 | -0.0262792 |
| FERMT1 | fermitin family member 1 | -0.0258336 |
| ABLIM1 | actin binding LIM protein 1 | -0.0255672 |
| RPL35A | ribosomal protein L35a | -0.0248856 |
| PRSS3 | protease, serine, 3 | -0.0248809 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0248657 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0247615 |
| RIN2 | Ras and Rab interactor 2 | -0.0245003 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0244526 |
| LSAMP | limbic system-associated membrane protein | -0.0243036 |
| RRBP1 | ribosome binding protein 1 | -0.0242723 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0242577 |
| TRIM2 | tripartite motif containing 2 | -0.0237849 |
| ETV6 | ets variant 6 | -0.0236751 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0234348 |
| SH3D19 | SH3 domain containing 19 | -0.0234124 |
| MYO1D | myosin ID | -0.0233063 |
| MECOM | MDS1 and EVI1 complex locus | -0.0232397 |
| NFIA | nuclear factor I/A | -0.0232297 |
| PCDHB16 | protocadherin beta 16 | -0.0232131 |
| HDLBP | high density lipoprotein binding protein | -0.0230555 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.023013 |
| FOSL1 | FOS-like antigen 1 | -0.0229307 |
| FRMD5 | FERM domain containing 5 | -0.0228312 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0227951 |
| RNF217 | ring finger protein 217 | -0.0227836 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0226718 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0222648 |
| DEK | DEK proto-oncogene | -0.0222249 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0221423 |
| IER3 | immediate early response 3 | -0.0220326 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0218033 |
| EGFR | epidermal growth factor receptor | -0.0214797 |
