| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.158739 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0829988 |
| GOLGA4 | golgin A4 | 0.0744863 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0740191 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0727878 |
| FTL | ferritin, light polypeptide | 0.0430255 |
| FAM13A | family with sequence similarity 13, member A | 0.0378004 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.037791 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0375437 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0363583 |
| PTMA | prothymosin, alpha | 0.0354372 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0351105 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0350699 |
| MT2A | metallothionein 2A | 0.0339142 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0337851 |
| CANX | calnexin | 0.0332024 |
| PCBP2 | poly(rC) binding protein 2 | 0.0326219 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0325705 |
| OGA | O-GlcNAcase | 0.0314132 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0306206 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0294187 |
| YBX3 | Y box binding protein 3 | 0.0292532 |
| YBX1 | Y box binding protein 1 | 0.0279675 |
| RPL23 | ribosomal protein L23 | 0.0277668 |
| RPL12 | ribosomal protein L12 | 0.0274276 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0271996 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0266137 |
| ANXA1 | annexin A1 | 0.0264503 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0260232 |
| SRP54 | signal recognition particle 54kDa | 0.0250318 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0240138 |
| RPLP0 | ribosomal protein, large, P0 | 0.0237868 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0237834 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0236594 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.023404 |
| YME1L1 | YME1-like 1 ATPase | 0.0224633 |
| SPAG9 | sperm associated antigen 9 | 0.022245 |
| RPS8 | ribosomal protein S8 | 0.0218629 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0207735 |
| RIOK3 | RIO kinase 3 | 0.0205438 |
| RPL7 | ribosomal protein L7 | 0.0202708 |
| RPLP1 | ribosomal protein, large, P1 | 0.0201837 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0197939 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0196478 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0195369 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0193934 |
| CLINT1 | clathrin interactor 1 | 0.0193556 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0193412 |
| ATP13A3 | ATPase type 13A3 | 0.0191935 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0189629 |
| KIF5B | kinesin family member 5B | 0.0188773 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0187686 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0185894 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0185591 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0184405 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0183905 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0183304 |
| COG5 | component of oligomeric golgi complex 5 | 0.0181473 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0181391 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0178333 |
| SUCO | SUN domain containing ossification factor | 0.0177255 |
| RNF145 | ring finger protein 145 | 0.0172866 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0172831 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0171349 |
| RPL31 | ribosomal protein L31 | 0.0170356 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0170207 |
| RBM39 | RNA binding motif protein 39 | 0.0168864 |
| USP3 | ubiquitin specific peptidase 3 | 0.0168346 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0166607 |
| ENO1 | enolase 1, (alpha) | 0.0166287 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0165318 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0163422 |
| RLF | rearranged L-myc fusion | 0.0158816 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0158541 |
| ZNF292 | zinc finger protein 292 | 0.0157928 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0157644 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0157397 |
| SLMAP | sarcolemma associated protein | 0.0156892 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0153849 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0153755 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.015375 |
| ARRDC3 | arrestin domain containing 3 | 0.0153736 |
| TPR | translocated promoter region, nuclear basket protein | 0.0153367 |
| KLF6 | Kruppel-like factor 6 | 0.0152873 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0152706 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0152638 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0149407 |
| RPS6 | ribosomal protein S6 | 0.0149361 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.014931 |
| XPO1 | exportin 1 | 0.0148226 |
| MYOF | myoferlin | 0.0147971 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0147895 |
| SERINC1 | serine incorporator 1 | 0.014718 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0147133 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0146786 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0146504 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0146483 |
| TGFB2 | transforming growth factor, beta 2 | 0.0146335 |
| RPL19 | ribosomal protein L19 | 0.01463 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0145789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.14929 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.142806 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.124685 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.101041 |
| CDH13 | cadherin 13 | -0.097345 |
| HMGA2 | high mobility group AT-hook 2 | -0.0954891 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0929504 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0812332 |
| NRG1 | neuregulin 1 | -0.0812165 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0789049 |
| TMSB10 | thymosin beta 10 | -0.0756992 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0740337 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0665354 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0627294 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0627147 |
| GLCCI1 | glucocorticoid induced 1 | -0.0614184 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0604707 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0591988 |
| FAM20C | family with sequence similarity 20, member C | -0.058655 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0580401 |
| MTSS1 | metastasis suppressor 1 | -0.0523475 |
| NRP1 | neuropilin 1 | -0.0515607 |
| LOX | lysyl oxidase | -0.0508068 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.049932 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0494649 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0493145 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0486841 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.047561 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0449428 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.043671 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0433771 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0407038 |
| CDK14 | cyclin-dependent kinase 14 | -0.0398232 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0390121 |
| GLIS3 | GLIS family zinc finger 3 | -0.0370107 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.036927 |
| RAI14 | retinoic acid induced 14 | -0.0369126 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0364863 |
| MEF2A | myocyte enhancer factor 2A | -0.0364348 |
| CLMP | CXADR-like membrane protein | -0.0362105 |
| SYT1 | synaptotagmin I | -0.0359996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0358976 |
| NDRG1 | N-myc downstream regulated 1 | -0.0353493 |
| RAD51B | RAD51 paralog B | -0.0350686 |
| OSMR | oncostatin M receptor | -0.0348806 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0348661 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0348527 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347577 |
| FBN1 | fibrillin 1 | -0.0336479 |
| CUX1 | cut-like homeobox 1 | -0.0331605 |
| DST | dystonin | -0.0329129 |
| OXR1 | oxidation resistance 1 | -0.0320976 |
| PKM | pyruvate kinase, muscle | -0.0320678 |
| IL1B | interleukin 1, beta | -0.0315301 |
| ETV6 | ets variant 6 | -0.031473 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0311765 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0307124 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0304712 |
| ZNF804A | zinc finger protein 804A | -0.0302739 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0301771 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0297322 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295688 |
| MECOM | MDS1 and EVI1 complex locus | -0.0294676 |
| PRKCA | protein kinase C, alpha | -0.0289563 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0288534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0287952 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0285248 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0279385 |
| IFI44L | interferon-induced protein 44-like | -0.0277306 |
| VEGFA | vascular endothelial growth factor A | -0.0276019 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0275196 |
| PRRX1 | paired related homeobox 1 | -0.0273128 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0272169 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0272159 |
| PRSS23 | protease, serine, 23 | -0.0270171 |
| NUMB | numb homolog (Drosophila) | -0.0268142 |
| SMAD3 | SMAD family member 3 | -0.0267429 |
| ATXN1 | ataxin 1 | -0.0267034 |
| VRK2 | vaccinia related kinase 2 | -0.0266587 |
| STC1 | stanniocalcin 1 | -0.0266188 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265994 |
| CDCP1 | CUB domain containing protein 1 | -0.0263186 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0262352 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0261483 |
| ATG7 | autophagy related 7 | -0.0260981 |
| SEPTIN9 | septin 9 | -0.0259651 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0258854 |
| EGR1 | early growth response 1 | -0.0256011 |
| GPC6 | glypican 6 | -0.0252008 |
| TMEM165 | transmembrane protein 165 | -0.0250974 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0248049 |
| ENOSF1 | enolase superfamily member 1 | -0.0248004 |
| WLS | wntless Wnt ligand secretion mediator | -0.0247739 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0245675 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0245509 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0245468 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0244753 |
| RNF213 | ring finger protein 213 | -0.0243816 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0243623 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0243482 |
