| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Loperamide (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.134876 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.128148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.111314 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.109059 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0911415 |
| CANX | calnexin | 0.0742083 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0718514 |
| ANLN | anillin, actin binding protein | 0.0699228 |
| VCL | vinculin | 0.0669867 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0661924 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0650692 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0640825 |
| LDHA | lactate dehydrogenase A | 0.0632178 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0593694 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0569709 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0565566 |
| HMGB2 | high mobility group box 2 | 0.055906 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0554131 |
| DIAPH3 | diaphanous-related formin 3 | 0.0548376 |
| PTMA | prothymosin, alpha | 0.0533438 |
| CALR | calreticulin | 0.0525464 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0512054 |
| ECT2 | epithelial cell transforming 2 | 0.049054 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0485312 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0478696 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0477858 |
| PHF3 | PHD finger protein 3 | 0.0467274 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.046544 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0465049 |
| PGK1 | phosphoglycerate kinase 1 | 0.0461146 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0459876 |
| AHNAK | AHNAK nucleoprotein | 0.0452612 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0451174 |
| KRT17 | keratin 17, type I | 0.0447127 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0443956 |
| CENPF | centromere protein F, 350/400kDa | 0.0441968 |
| MKI67 | marker of proliferation Ki-67 | 0.0436908 |
| RPS3 | ribosomal protein S3 | 0.0409506 |
| ANXA2 | annexin A2 | 0.0397633 |
| ENO1 | enolase 1, (alpha) | 0.0395338 |
| INTS6 | integrator complex subunit 6 | 0.0389461 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0388821 |
| OGA | O-GlcNAcase | 0.0386947 |
| LIMA1 | LIM domain and actin binding 1 | 0.0385964 |
| RLF | rearranged L-myc fusion | 0.038295 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0378088 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365987 |
| RPL23 | ribosomal protein L23 | 0.0362015 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0357493 |
| SPAG9 | sperm associated antigen 9 | 0.0355817 |
| KIF5B | kinesin family member 5B | 0.0354471 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0350349 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0345836 |
| EPCAM | epithelial cell adhesion molecule | 0.0345519 |
| TMSB4X | thymosin beta 4, X-linked | 0.03417 |
| PTK2 | protein tyrosine kinase 2 | 0.0340152 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0336988 |
| EFNA5 | ephrin-A5 | 0.0332302 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0328939 |
| SERINC1 | serine incorporator 1 | 0.0327861 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0327855 |
| EZR | ezrin | 0.0325258 |
| GOLGA4 | golgin A4 | 0.0321483 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0321458 |
| LAMC2 | laminin, gamma 2 | 0.0319712 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0318951 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0316998 |
| SDC4 | syndecan 4 | 0.0316482 |
| RACK1 | receptor for activated C kinase 1 | 0.0306411 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0306363 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.03038 |
| WWC1 | WW and C2 domain containing 1 | 0.0302 |
| RYK | receptor-like tyrosine kinase | 0.0299709 |
| NFIB | nuclear factor I/B | 0.0299263 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0297003 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0295875 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0293584 |
| TPX2 | TPX2, microtubule-associated | 0.029349 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0291739 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | 0.0284692 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.0283206 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0282376 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0280991 |
| SEPTIN7 | septin 7 | 0.0279103 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0275605 |
| PLK2 | polo-like kinase 2 | 0.0273115 |
| SHROOM3 | shroom family member 3 | 0.02704 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0268466 |
| KRT8 | keratin 8, type II | 0.0265477 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0261609 |
| KRT18 | keratin 18, type I | 0.0255814 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.02541 |
| STAG2 | stromal antigen 2 | 0.0253554 |
| CAVIN1 | caveolae associated protein 1 | 0.0253195 |
| TMF1 | TATA element modulatory factor 1 | 0.0250667 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0249123 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0248869 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0246723 |
| ATP13A3 | ATPase type 13A3 | 0.02447 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0244366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA1 | high mobility group AT-hook 1 | -0.128135 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.110464 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0970694 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0903992 |
| FN1 | fibronectin 1 | -0.0843207 |
| POTEF | POTE ankyrin domain family, member F | -0.0757259 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0755408 |
| ACTG1 | actin gamma 1 | -0.0754829 |
| MUC4 | mucin 4, cell surface associated | -0.0713446 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0640834 |
| JUP | junction plakoglobin | -0.0635757 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0625869 |
| LMO7 | LIM domain 7 | -0.0594298 |
| MUC16 | mucin 16, cell surface associated | -0.0591444 |
| LAMA4 | laminin, alpha 4 | -0.0559836 |
| RNF213 | ring finger protein 213 | -0.0546304 |
| VEGFA | vascular endothelial growth factor A | -0.0534792 |
| TJP1 | tight junction protein 1 | -0.0531886 |
| RPS6 | ribosomal protein S6 | -0.0492099 |
| C3 | complement component 3 | -0.0490565 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0488074 |
| TPM4 | tropomyosin 4 | -0.0487525 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0476468 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0470955 |
| SULF2 | sulfatase 2 | -0.0456504 |
| MYO1E | myosin IE | -0.0453357 |
| MX2 | MX dynamin-like GTPase 2 | -0.0447707 |
| EMP1 | epithelial membrane protein 1 | -0.0444862 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0440341 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0435891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.043473 |
| BRD4 | bromodomain containing 4 | -0.0422759 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0419897 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0417469 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0412989 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0400229 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0396764 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0395178 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0383339 |
| NDRG1 | N-myc downstream regulated 1 | -0.038301 |
| FNBP4 | formin binding protein 4 | -0.0382606 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0380714 |
| EGR1 | early growth response 1 | -0.0380665 |
| CLDN4 | claudin 4 | -0.0380658 |
| SVIL | supervillin | -0.0370677 |
| SYT14 | synaptotagmin XIV | -0.0358831 |
| MEF2A | myocyte enhancer factor 2A | -0.0350387 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0343849 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0340547 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0339827 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0337414 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0336143 |
| CD44 | CD44 molecule (Indian blood group) | -0.0332772 |
| CCND1 | cyclin D1 | -0.0329493 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.032759 |
| RPL35A | ribosomal protein L35a | -0.0325882 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0322568 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0315053 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0310176 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0310161 |
| SNX9 | sorting nexin 9 | -0.0308632 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0298847 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0297774 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0296268 |
| ASS1 | argininosuccinate synthase 1 | -0.0296201 |
| OXSR1 | oxidative stress responsive 1 | -0.0295634 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295481 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.029486 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0290141 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0287738 |
| LIPH | lipase, member H | -0.0287663 |
| DUSP5 | dual specificity phosphatase 5 | -0.0285786 |
| LAMA5 | laminin, alpha 5 | -0.0285281 |
| ERBIN | erbb2 interacting protein | -0.0283109 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0279577 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0279473 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0279432 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0279276 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0277552 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0275324 |
| FMNL2 | formin-like 2 | -0.02722 |
| FTL | ferritin, light polypeptide | -0.0271565 |
| CCNL1 | cyclin L1 | -0.0269233 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0266426 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0262204 |
| EFNB2 | ephrin-B2 | -0.0262029 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0255061 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0255059 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0252283 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0252189 |
| HLA-A | major histocompatibility complex, class I, A | -0.0251976 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0251243 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0251164 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.02491 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0248797 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0248187 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0248122 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0247905 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0247137 |
| CDYL | chromodomain protein, Y-like | -0.0246138 |
