| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Loperamide (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0692726 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0601414 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0582095 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0557413 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0535291 |
| CANX | calnexin | 0.047688 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471937 |
| LDHA | lactate dehydrogenase A | 0.0464336 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0422587 |
| SET | SET nuclear proto-oncogene | 0.0404723 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0401393 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0398762 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0359624 |
| ECT2 | epithelial cell transforming 2 | 0.0357081 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0340712 |
| NUP58 | nucleoporin 58 | 0.0340179 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.032713 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317831 |
| YBX3 | Y box binding protein 3 | 0.0314802 |
| DTNA | dystrobrevin, alpha | 0.0304452 |
| CENPF | centromere protein F, 350/400kDa | 0.0302003 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0299638 |
| ATP13A3 | ATPase type 13A3 | 0.029858 |
| HMGB2 | high mobility group box 2 | 0.0294328 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0292513 |
| GOLGA4 | golgin A4 | 0.0289781 |
| DNER | delta/notch-like EGF repeat containing | 0.0288693 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0288113 |
| ZNF292 | zinc finger protein 292 | 0.0284703 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0283115 |
| TPX2 | TPX2, microtubule-associated | 0.0282127 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0281754 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0278061 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.027753 |
| ANXA1 | annexin A1 | 0.0275437 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271957 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0270381 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270271 |
| QKI | QKI, KH domain containing, RNA binding | 0.0270148 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0266127 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0263914 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.025751 |
| SEC24A | SEC24 family member A | 0.0253789 |
| TPR | translocated promoter region, nuclear basket protein | 0.0249358 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0248949 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0248222 |
| TMF1 | TATA element modulatory factor 1 | 0.0245442 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0244812 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0242582 |
| KIF5B | kinesin family member 5B | 0.0238428 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0236412 |
| ANLN | anillin, actin binding protein | 0.0235777 |
| TFG | TRK-fused gene | 0.0234253 |
| XPO1 | exportin 1 | 0.0233332 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0232929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0231099 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230918 |
| HELZ | helicase with zinc finger | 0.0229311 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0228616 |
| HLTF | helicase-like transcription factor | 0.0228121 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0226537 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.022633 |
| ENO1 | enolase 1, (alpha) | 0.0224749 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0224273 |
| JMJD1C | jumonji domain containing 1C | 0.0223676 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0222363 |
| PNN | pinin, desmosome associated protein | 0.0221747 |
| ZFR | zinc finger RNA binding protein | 0.0220663 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0217588 |
| CAPRIN2 | caprin family member 2 | 0.0213819 |
| WBP11 | WW domain binding protein 11 | 0.0213196 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0213018 |
| PGM3 | phosphoglucomutase 3 | 0.0211967 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0211372 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0211306 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0208883 |
| RHEB | Ras homolog enriched in brain | 0.0208305 |
| ZNF207 | zinc finger protein 207 | 0.0207572 |
| RACK1 | receptor for activated C kinase 1 | 0.0206173 |
| MED12 | mediator complex subunit 12 | 0.0206166 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0202797 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0202342 |
| RAB14 | RAB14, member RAS oncogene family | 0.0202076 |
| MATR3 | matrin 3 | 0.0201932 |
| ZNF638 | zinc finger protein 638 | 0.0201774 |
| CEP170 | centrosomal protein 170kDa | 0.0200967 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0200326 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0199939 |
| TTK | TTK protein kinase | 0.0199692 |
| WDR36 | WD repeat domain 36 | 0.0199522 |
| USP37 | ubiquitin specific peptidase 37 | 0.0198935 |
| RNF145 | ring finger protein 145 | 0.0195174 |
| IPO7 | importin 7 | 0.0194678 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0194593 |
| RPL34 | ribosomal protein L34 | 0.0194484 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0193019 |
| UBQLN1 | ubiquilin 1 | 0.0192891 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0192812 |
| CDK17 | cyclin-dependent kinase 17 | 0.0192117 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0191693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174866 |
| RPLP1 | ribosomal protein, large, P1 | -0.0803694 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0793924 |
| MT2A | metallothionein 2A | -0.0543856 |
| HMGA2 | high mobility group AT-hook 2 | -0.0537952 |
| OSMR | oncostatin M receptor | -0.0506307 |
| IGF2 | insulin-like growth factor 2 | -0.0479371 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0443411 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0435649 |
| RPL35A | ribosomal protein L35a | -0.0422123 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0416878 |
| NF1 | neurofibromin 1 | -0.0405965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0393527 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0377981 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.036823 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0368136 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.036707 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0362029 |
| PRKCA | protein kinase C, alpha | -0.0361709 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0356467 |
| GNAS | GNAS complex locus | -0.0353739 |
| FN1 | fibronectin 1 | -0.0346371 |
| TMSB10 | thymosin beta 10 | -0.0345351 |
| EGR1 | early growth response 1 | -0.0344544 |
| RPS13 | ribosomal protein S13 | -0.0342164 |
| FTL | ferritin, light polypeptide | -0.0338269 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0337457 |
| EGFR | epidermal growth factor receptor | -0.0335452 |
| RPL37 | ribosomal protein L37 | -0.0327222 |
| RPL12 | ribosomal protein L12 | -0.0316578 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0315772 |
| HLA-B | major histocompatibility complex, class I, B | -0.0312355 |
| NDRG1 | N-myc downstream regulated 1 | -0.0311979 |
| RPLP2 | ribosomal protein, large, P2 | -0.0309611 |
| SDC4 | syndecan 4 | -0.0307561 |
| PKM | pyruvate kinase, muscle | -0.0302827 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0302039 |
| RPL23 | ribosomal protein L23 | -0.0300398 |
| INTS6 | integrator complex subunit 6 | -0.029713 |
| POTEF | POTE ankyrin domain family, member F | -0.0295876 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0294811 |
| PTK2 | protein tyrosine kinase 2 | -0.0293106 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0290429 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289329 |
| HLA-A | major histocompatibility complex, class I, A | -0.0279675 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0275958 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275794 |
| GPHN | gephyrin | -0.0273325 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0268329 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0267737 |
| CCNH | cyclin H | -0.0265329 |
| RNF213 | ring finger protein 213 | -0.0263909 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0263221 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0262955 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0262503 |
| SBF2 | SET binding factor 2 | -0.0262406 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0257436 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0255565 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.025521 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255118 |
| IER3 | immediate early response 3 | -0.0254938 |
| TCF12 | transcription factor 12 | -0.0254416 |
| PRELID2 | PRELI domain containing 2 | -0.0253653 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0252832 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0252624 |
| STXBP1 | syntaxin binding protein 1 | -0.0252109 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.025161 |
| ASPH | aspartate beta-hydroxylase | -0.0249725 |
| RPL36 | ribosomal protein L36 | -0.0249653 |
| CFDP1 | craniofacial development protein 1 | -0.0249208 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0247075 |
| VIM | vimentin | -0.0246557 |
| TAOK3 | TAO kinase 3 | -0.0246474 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0245965 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0245255 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0243055 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0242095 |
| SEM1 | SEM1 26S proteasome subunit | -0.0240834 |
| RPL19 | ribosomal protein L19 | -0.0238322 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.023726 |
| PRKD3 | protein kinase D3 | -0.0235948 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0235843 |
| RPS29 | ribosomal protein S29 | -0.0235381 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0234577 |
| MYO9B | myosin IXB | -0.0230781 |
| ATXN2 | ataxin 2 | -0.0228861 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0226371 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0226067 |
| SMAD3 | SMAD family member 3 | -0.0223449 |
| VCL | vinculin | -0.0220494 |
| AOPEP | aminopeptidase O (putative) | -0.0220173 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0218627 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0217027 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0216704 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0215738 |
| ACTG1 | actin gamma 1 | -0.0215721 |
| GDI1 | GDP dissociation inhibitor 1 | -0.0213929 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212909 |
| SVIL | supervillin | -0.0211597 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0209277 |
