| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Loperamide (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Loperamide (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0664575 |
| RPS6 | ribosomal protein S6 | 0.0473102 |
| CENPF | centromere protein F, 350/400kDa | 0.0458165 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405404 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0384787 |
| VIM | vimentin | 0.0361553 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0345386 |
| ENO1 | enolase 1, (alpha) | 0.0330498 |
| SET | SET nuclear proto-oncogene | 0.0281247 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0281041 |
| RPS12 | ribosomal protein S12 | 0.0280806 |
| OXR1 | oxidation resistance 1 | 0.0270582 |
| RPS3 | ribosomal protein S3 | 0.0245985 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0245729 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.024435 |
| RPS8 | ribosomal protein S8 | 0.021528 |
| RPL23 | ribosomal protein L23 | 0.0215037 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214342 |
| RPS19 | ribosomal protein S19 | 0.0213219 |
| MKI67 | marker of proliferation Ki-67 | 0.0212041 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0209677 |
| RPL21 | ribosomal protein L21 | 0.0208816 |
| PROX1 | prospero homeobox 1 | 0.0205849 |
| RPLP2 | ribosomal protein, large, P2 | 0.0196833 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0195582 |
| POTEF | POTE ankyrin domain family, member F | 0.019223 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0185437 |
| DSPP | dentin sialophosphoprotein | 0.0180817 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0180621 |
| YBX1 | Y box binding protein 1 | 0.0176973 |
| RPL10A | ribosomal protein L10a | 0.0175755 |
| PCM1 | pericentriolar material 1 | 0.0172933 |
| TXNIP | thioredoxin interacting protein | 0.0172379 |
| LDHA | lactate dehydrogenase A | 0.0167661 |
| RPL7 | ribosomal protein L7 | 0.0167182 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0166624 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0164703 |
| SYT1 | synaptotagmin I | 0.0163925 |
| RPS27 | ribosomal protein S27 | 0.0162766 |
| CBX3 | chromobox homolog 3 | 0.0162556 |
| RPL37A | ribosomal protein L37a | 0.0161604 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0160636 |
| TUBA1B | tubulin, alpha 1b | 0.0159142 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0155993 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0154161 |
| RPS14 | ribosomal protein S14 | 0.0150399 |
| MT2A | metallothionein 2A | 0.0150257 |
| RPL26 | ribosomal protein L26 | 0.014854 |
| FOXP1 | forkhead box P1 | 0.0147866 |
| PFN1 | profilin 1 | 0.0143308 |
| TPX2 | TPX2, microtubule-associated | 0.0141389 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0141125 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0140002 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0136414 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0135236 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0135197 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0134566 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0134344 |
| RPL31 | ribosomal protein L31 | 0.0133269 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0131337 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0129659 |
| FTL | ferritin, light polypeptide | 0.0128671 |
| RPL12 | ribosomal protein L12 | 0.0128121 |
| KIF5B | kinesin family member 5B | 0.0127783 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0126857 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0126802 |
| RPL11 | ribosomal protein L11 | 0.0124993 |
| RPS4X | ribosomal protein S4, X-linked | 0.0124841 |
| RPL18 | ribosomal protein L18 | 0.0124727 |
| TMF1 | TATA element modulatory factor 1 | 0.0123961 |
| DST | dystonin | 0.0123243 |
| RPS13 | ribosomal protein S13 | 0.0122074 |
| RPLP1 | ribosomal protein, large, P1 | 0.0121908 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0121291 |
| RPL19 | ribosomal protein L19 | 0.0120358 |
| PNN | pinin, desmosome associated protein | 0.012031 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0119495 |
| RPS2 | ribosomal protein S2 | 0.0119014 |
| RPS17 | ribosomal protein S17 | 0.0117437 |
| CEP57 | centrosomal protein 57kDa | 0.0116905 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.011597 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0114903 |
| RPL36A | ribosomal protein L36a | 0.0114672 |
| PLIN2 | perilipin 2 | 0.0114482 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0112799 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0112409 |
| TPI1 | triosephosphate isomerase 1 | 0.0111127 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0110897 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0109992 |
| RPL9 | ribosomal protein L9 | 0.0109178 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0109106 |
| SGO2 | shugoshin 2 | 0.0109103 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0108201 |
| MSN | moesin | 0.0107843 |
| RACK1 | receptor for activated C kinase 1 | 0.0107153 |
| RPL3 | ribosomal protein L3 | 0.0105903 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0104916 |
| LDHB | lactate dehydrogenase B | 0.0104351 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0103501 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0102845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.0868762 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0780732 |
| NAV2 | neuron navigator 2 | -0.0728809 |
| INTS6 | integrator complex subunit 6 | -0.0681774 |
| AHNAK | AHNAK nucleoprotein | -0.0629764 |
| CDH13 | cadherin 13 | -0.062313 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.054492 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0542118 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0474988 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0451545 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0379217 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0358208 |
| CCND1 | cyclin D1 | -0.0350543 |
| ANKRD10 | ankyrin repeat domain 10 | -0.032931 |
| ASPH | aspartate beta-hydroxylase | -0.0327666 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0327295 |
| FRMD5 | FERM domain containing 5 | -0.0317387 |
| ANXA2 | annexin A2 | -0.0316927 |
| PLEC | plectin | -0.0301426 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0295438 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0293058 |
| HDAC4 | histone deacetylase 4 | -0.0292381 |
| KRT8 | keratin 8, type II | -0.0276043 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0273714 |
| ACTN4 | actinin, alpha 4 | -0.0271823 |
| ATXN1 | ataxin 1 | -0.0268472 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0253797 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0253541 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0252681 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0249122 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0246383 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245074 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0242766 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0235638 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0229199 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0226467 |
| UBAP2 | ubiquitin associated protein 2 | -0.0225086 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0216705 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0213829 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0208635 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0207894 |
| FUS | FUS RNA binding protein | -0.0207591 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0203452 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0202364 |
| TFRC | transferrin receptor | -0.0200364 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0199083 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0197706 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0196135 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.01945 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0190474 |
| EZR | ezrin | -0.0189454 |
| H1-0 | H1.0 linker histone | -0.0189258 |
| CDK13 | cyclin-dependent kinase 13 | -0.0188294 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0187788 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0187754 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0187319 |
| CDK6 | cyclin-dependent kinase 6 | -0.018256 |
| FMNL2 | formin-like 2 | -0.0182132 |
| CUX1 | cut-like homeobox 1 | -0.0180503 |
| RCOR1 | REST corepressor 1 | -0.0177769 |
| RBM39 | RNA binding motif protein 39 | -0.0174483 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0174473 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0174272 |
| COG5 | component of oligomeric golgi complex 5 | -0.0169556 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0169167 |
| FLNB | filamin B, beta | -0.0168704 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0167999 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.016545 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0165302 |
| ACTG1 | actin gamma 1 | -0.0164386 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0163907 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0163324 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0162664 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0161064 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0159842 |
| MYO1D | myosin ID | -0.0159743 |
| MYOF | myoferlin | -0.0158304 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0157246 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0156979 |
| PRKCA | protein kinase C, alpha | -0.0156166 |
| RPS24 | ribosomal protein S24 | -0.0155067 |
| JMJD1C | jumonji domain containing 1C | -0.0154032 |
| NDRG1 | N-myc downstream regulated 1 | -0.015256 |
| WWOX | WW domain containing oxidoreductase | -0.0152437 |
| HPCAL1 | hippocalcin-like 1 | -0.0151651 |
| RAD51B | RAD51 paralog B | -0.0150155 |
| GLG1 | golgi glycoprotein 1 | -0.0150058 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0149532 |
| FLNA | filamin A, alpha | -0.014947 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0148564 |
| TCF12 | transcription factor 12 | -0.0147472 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0147427 |
| MSI2 | musashi RNA-binding protein 2 | -0.0146461 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0145591 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0143963 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0143751 |
| NHSL1 | NHS-like 1 | -0.014311 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0142332 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0138538 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.013532 |
