| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306475 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0275311 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212629 |
| HMGB2 | high mobility group box 2 | 0.0204229 |
| LMNA | lamin A/C | 0.0171296 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0167213 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0160198 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0156483 |
| RPL3 | ribosomal protein L3 | 0.0151743 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0148771 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0147673 |
| CCNG2 | cyclin G2 | 0.0141971 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0138582 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0136164 |
| RLF | rearranged L-myc fusion | 0.0135441 |
| LPIN1 | lipin 1 | 0.0132059 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0131445 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0125593 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0125496 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.012371 |
| HSPA8 | heat shock 70kDa protein 8 | 0.012173 |
| UBQLN1 | ubiquilin 1 | 0.0121156 |
| RNF145 | ring finger protein 145 | 0.0120608 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0118701 |
| FAM13A | family with sequence similarity 13, member A | 0.0118619 |
| HELZ | helicase with zinc finger | 0.0115646 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0115238 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0114006 |
| ANGPTL4 | angiopoietin-like 4 | 0.0111117 |
| OXSR1 | oxidative stress responsive 1 | 0.0110782 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0110139 |
| TUFT1 | tuftelin 1 | 0.0107568 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0105035 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0104913 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0103686 |
| SPAG9 | sperm associated antigen 9 | 0.010218 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0101921 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0101525 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.010089 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0100163 |
| SRP54 | signal recognition particle 54kDa | 0.00993707 |
| CENPC | centromere protein C | 0.00984179 |
| RBM33 | RNA binding motif protein 33 | 0.00979932 |
| ACLY | ATP citrate lyase | 0.00967089 |
| H1-4 | H1.4 linker histone, cluster member | 0.00965591 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00959681 |
| PAPOLA | poly(A) polymerase alpha | 0.00954442 |
| XPO1 | exportin 1 | 0.00952834 |
| RPSA | ribosomal protein SA | 0.00951462 |
| PLEC | plectin | 0.0094926 |
| FDXR | ferredoxin reductase | 0.00934063 |
| LRRC59 | leucine rich repeat containing 59 | 0.00929046 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00910951 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00882566 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00881391 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.008774 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00873365 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.00868353 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.00861838 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00861505 |
| SMAD3 | SMAD family member 3 | 0.00861025 |
| VGF | VGF nerve growth factor inducible | 0.00852359 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.00852191 |
| COG6 | component of oligomeric golgi complex 6 | 0.00848774 |
| SEPTIN9 | septin 9 | 0.00837946 |
| YTHDC1 | YTH domain containing 1 | 0.00834266 |
| GPR107 | G protein-coupled receptor 107 | 0.00833398 |
| SUCO | SUN domain containing ossification factor | 0.00812635 |
| ARRDC3 | arrestin domain containing 3 | 0.00809339 |
| KIF5B | kinesin family member 5B | 0.00809213 |
| COPA | coatomer protein complex, subunit alpha | 0.00804121 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00803357 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.00802634 |
| LRRC1 | leucine rich repeat containing 1 | 0.0080147 |
| YY1AP1 | YY1 associated protein 1 | 0.0079946 |
| TPM3 | tropomyosin 3 | 0.0078907 |
| RPS18 | ribosomal protein S18 | 0.00787341 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00785895 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.00781196 |
| RYBP | RING1 and YY1 binding protein | 0.00777687 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00772079 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.00772008 |
| ATOSA | atos homolog A | 0.00763352 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00760502 |
| ABI2 | abl-interactor 2 | 0.00752212 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00751461 |
| CCNT2 | cyclin T2 | 0.00743739 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00742994 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00741867 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00741734 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00741413 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00739443 |
| CDK8 | cyclin-dependent kinase 8 | 0.00738727 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.00738223 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00734546 |
| SAFB2 | scaffold attachment factor B2 | 0.00732092 |
| VASN | vasorin | 0.00730307 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00728444 |
| TOP1 | topoisomerase (DNA) I | 0.00726841 |
| ZNF160 | zinc finger protein 160 | 0.00720883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.383018 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.180201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143952 |
| LSAMP | limbic system-associated membrane protein | -0.102087 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0928728 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0851204 |
| MEIS2 | Meis homeobox 2 | -0.0764749 |
| SYT1 | synaptotagmin I | -0.0745364 |
| VIM | vimentin | -0.0644839 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0631141 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0581004 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0576675 |
| RPS6 | ribosomal protein S6 | -0.0575336 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.056419 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0562581 |
| PTMA | prothymosin, alpha | -0.0546175 |
| NRG1 | neuregulin 1 | -0.0544651 |
| RPL35A | ribosomal protein L35a | -0.0513974 |
| COL1A1 | collagen, type I, alpha 1 | -0.049307 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0488053 |
| BPTF | bromodomain PHD finger transcription factor | -0.0479479 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0441863 |
| ACTG1 | actin gamma 1 | -0.0432882 |
| RPL23 | ribosomal protein L23 | -0.0428982 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0427673 |
| FMN1 | formin 1 | -0.042251 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0414453 |
| KLHL13 | kelch-like family member 13 | -0.0373446 |
| RPS24 | ribosomal protein S24 | -0.0363207 |
| NREP | neuronal regeneration related protein | -0.0351809 |
| PRKCA | protein kinase C, alpha | -0.0347203 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0341992 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0338879 |
| RPL19 | ribosomal protein L19 | -0.032874 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0328398 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0327598 |
| CADM2 | cell adhesion molecule 2 | -0.0321115 |
| TMSB10 | thymosin beta 10 | -0.0318924 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0318706 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0315884 |
| RPL34 | ribosomal protein L34 | -0.0315757 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0312355 |
| ZNF804A | zinc finger protein 804A | -0.0312244 |
| RPL38 | ribosomal protein L38 | -0.0308371 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0306021 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.030137 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0299921 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0295056 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293768 |
| CRH | corticotropin releasing hormone | -0.0290418 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0280956 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0277585 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0277458 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.027494 |
| RPS3 | ribosomal protein S3 | -0.0272944 |
| PLAT | plasminogen activator, tissue | -0.0270665 |
| RPLP0 | ribosomal protein, large, P0 | -0.0266191 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0266004 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0263105 |
| DPH6 | diphthamine biosynthesis 6 | -0.0260298 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0259482 |
| MSI2 | musashi RNA-binding protein 2 | -0.0252729 |
| PCDH9 | protocadherin 9 | -0.0251178 |
| NDRG1 | N-myc downstream regulated 1 | -0.0251026 |
| DNM3 | dynamin 3 | -0.0250136 |
| SMYD3 | SET and MYND domain containing 3 | -0.0249146 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0248455 |
| MAP1B | microtubule-associated protein 1B | -0.0244146 |
| CUX1 | cut-like homeobox 1 | -0.0242829 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0240123 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0239182 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0238873 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.023832 |
| COL3A1 | collagen, type III, alpha 1 | -0.0237426 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0237308 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0235537 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0234738 |
| DIAPH2 | diaphanous-related formin 2 | -0.0234632 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0231262 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0230185 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0229868 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.022528 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0224945 |
| ZNF609 | zinc finger protein 609 | -0.0224688 |
| HIP1 | huntingtin interacting protein 1 | -0.0223298 |
| RPS8 | ribosomal protein S8 | -0.0222482 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0222431 |
| FNBP1 | formin binding protein 1 | -0.0221264 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0221075 |
| RPS19 | ribosomal protein S19 | -0.0220616 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0220424 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0220121 |
| RAD51B | RAD51 paralog B | -0.021992 |
| NBEA | neurobeachin | -0.0217332 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211391 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0210505 |
| RPL32 | ribosomal protein L32 | -0.0207243 |
| RPS29 | ribosomal protein S29 | -0.0206571 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0203788 |
| VMP1 | vacuole membrane protein 1 | -0.0202446 |
