| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.175462 |
| INTS6 | integrator complex subunit 6 | 0.133907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.128168 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.111281 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.103605 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0957094 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0738913 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0654414 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0649889 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0600877 |
| PLSCR2 | phospholipid scramblase 2 | 0.0595157 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0585891 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.05712 |
| PRELID2 | PRELI domain containing 2 | 0.0492354 |
| RNF213 | ring finger protein 213 | 0.0478428 |
| HDLBP | high density lipoprotein binding protein | 0.046695 |
| SMAD3 | SMAD family member 3 | 0.0418726 |
| EFNB2 | ephrin-B2 | 0.0418441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0412471 |
| AHNAK | AHNAK nucleoprotein | 0.0409564 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.040902 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.038467 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0382027 |
| RUNX1 | runt-related transcription factor 1 | 0.0380041 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0375282 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0375024 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0374659 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0347603 |
| STK24 | serine/threonine kinase 24 | 0.0346434 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0336063 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0333118 |
| H1-0 | H1.0 linker histone | 0.0329979 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0329622 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0316723 |
| RNF43 | ring finger protein 43 | 0.0315937 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0313351 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0301105 |
| EREG | epiregulin | 0.0299375 |
| SERINC5 | serine incorporator 5 | 0.0292547 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0285568 |
| SP100 | SP100 nuclear antigen | 0.0275838 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0267585 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0266584 |
| DSPP | dentin sialophosphoprotein | 0.0266393 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0261796 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0260386 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0259186 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0257126 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0251331 |
| LMO7 | LIM domain 7 | 0.0248173 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0247657 |
| VCL | vinculin | 0.0247555 |
| TOX3 | TOX high mobility group box family member 3 | 0.0246925 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0245197 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0244222 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0244072 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0243056 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0241398 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0237093 |
| UTRN | utrophin | 0.0236687 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0235418 |
| PHF3 | PHD finger protein 3 | 0.0235306 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0234057 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0233027 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0232906 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0231142 |
| MED13 | mediator complex subunit 13 | 0.0230777 |
| SBF2 | SET binding factor 2 | 0.0226689 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.022574 |
| TBPL1 | TBP-like 1 | 0.0225643 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.022478 |
| CTBP2 | C-terminal binding protein 2 | 0.0223681 |
| EHF | ets homologous factor | 0.0222577 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0222227 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0222133 |
| ACTN4 | actinin, alpha 4 | 0.0221081 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0220253 |
| ATXN1 | ataxin 1 | 0.0219447 |
| EXOC4 | exocyst complex component 4 | 0.0218649 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0211657 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0211277 |
| CANX | calnexin | 0.0209001 |
| ASPH | aspartate beta-hydroxylase | 0.0208488 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0208387 |
| SUCO | SUN domain containing ossification factor | 0.0207875 |
| FOXP1 | forkhead box P1 | 0.0207778 |
| YAP1 | Yes-associated protein 1 | 0.0206877 |
| GOLGA2 | golgin A2 | 0.0205371 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0204878 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0204388 |
| CUL3 | cullin 3 | 0.0204066 |
| IFNGR1 | interferon gamma receptor 1 | 0.0203044 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0202565 |
| DIAPH3 | diaphanous-related formin 3 | 0.0202325 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0202294 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0202043 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0201361 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.020069 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0200392 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0198453 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.173853 |
| LYZ | lysozyme | -0.120686 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112906 |
| EGR1 | early growth response 1 | -0.10173 |
| HLA-B | major histocompatibility complex, class I, B | -0.0848132 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0846052 |
| LCN2 | lipocalin 2 | -0.0819173 |
| PTMA | prothymosin, alpha | -0.0739299 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0709542 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0664719 |
| TMC5 | transmembrane channel-like 5 | -0.0648098 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0615622 |
| POTEF | POTE ankyrin domain family, member F | -0.0606914 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0606636 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0593482 |
| NDRG1 | N-myc downstream regulated 1 | -0.0584831 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0581026 |
| FTL | ferritin, light polypeptide | -0.0578039 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0565345 |
| ERBIN | erbb2 interacting protein | -0.0546508 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0545888 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0510917 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0508387 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0499652 |
| RPS6 | ribosomal protein S6 | -0.0496201 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0460247 |
| RPL35A | ribosomal protein L35a | -0.0459183 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0451319 |
| MX1 | MX dynamin-like GTPase 1 | -0.0450549 |
| TMSB10 | thymosin beta 10 | -0.0426384 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0419786 |
| EZR | ezrin | -0.0419554 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0397488 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0394563 |
| AREG | amphiregulin | -0.0389789 |
| HLA-A | major histocompatibility complex, class I, A | -0.0379919 |
| CSTB | cystatin B (stefin B) | -0.0369311 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0366109 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0362866 |
| UBC | ubiquitin C | -0.0358518 |
| DSTN | destrin (actin depolymerizing factor) | -0.0351014 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0346395 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0340917 |
| S100A6 | S100 calcium binding protein A6 | -0.0327532 |
| MT2A | metallothionein 2A | -0.0326711 |
| MCL1 | myeloid cell leukemia 1 | -0.0326081 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0322359 |
| WDR45B | WD repeat domain 45B | -0.0321907 |
| ZNF609 | zinc finger protein 609 | -0.0318192 |
| CST3 | cystatin C | -0.0315215 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0314416 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.031369 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0308715 |
| VEGFA | vascular endothelial growth factor A | -0.0307556 |
| RPL34 | ribosomal protein L34 | -0.0306359 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0304289 |
| POMP | proteasome maturation protein | -0.0302417 |
| CCNL1 | cyclin L1 | -0.0300985 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0300504 |
| DIAPH1 | diaphanous-related formin 1 | -0.0298426 |
| RPS8 | ribosomal protein S8 | -0.0293294 |
| ACTG1 | actin gamma 1 | -0.0291516 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0291051 |
| HM13 | histocompatibility (minor) 13 | -0.0283612 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0283278 |
| S100A9 | S100 calcium binding protein A9 | -0.0277243 |
| EFHD2 | EF-hand domain family, member D2 | -0.0272203 |
| RPS19 | ribosomal protein S19 | -0.0271406 |
| ZNF292 | zinc finger protein 292 | -0.0270248 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0270047 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0269999 |
| RPLP1 | ribosomal protein, large, P1 | -0.026947 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0269469 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0269288 |
| JUN | jun proto-oncogene | -0.0264991 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0262795 |
| RPLP0 | ribosomal protein, large, P0 | -0.026273 |
| PTGR1 | prostaglandin reductase 1 | -0.0259023 |
| PERP | PERP, TP53 apoptosis effector | -0.0258573 |
| TFF3 | trefoil factor 3 (intestinal) | -0.025775 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0257005 |
| SPATA13 | spermatogenesis associated 13 | -0.0255481 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0255047 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0254488 |
| RPS13 | ribosomal protein S13 | -0.0253563 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0252606 |
| ATF4 | activating transcription factor 4 | -0.0252499 |
| XDH | xanthine dehydrogenase | -0.0252016 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0251311 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0249698 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0248625 |
| RPL37A | ribosomal protein L37a | -0.0245343 |
| RPS27 | ribosomal protein S27 | -0.0245023 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0244015 |
| HLA-C | major histocompatibility complex, class I, C | -0.024385 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024225 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0242133 |
| FHL2 | four and a half LIM domains 2 | -0.0241177 |
| YBX3 | Y box binding protein 3 | -0.024088 |
| CLDN4 | claudin 4 | -0.0237841 |
