| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.197659 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0779222 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0716255 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0635867 |
| HYOU1 | hypoxia up-regulated 1 | 0.0566928 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0544526 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0434252 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0415838 |
| DSPP | dentin sialophosphoprotein | 0.0384239 |
| LMO7 | LIM domain 7 | 0.0363935 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0341722 |
| PLEC | plectin | 0.0340782 |
| AHNAK | AHNAK nucleoprotein | 0.033757 |
| PMM2 | phosphomannomutase 2 | 0.032517 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0324626 |
| GOLGB1 | golgin B1 | 0.0312873 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.030905 |
| GOLGA4 | golgin A4 | 0.0298949 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0292693 |
| CLTC | clathrin, heavy chain (Hc) | 0.0288916 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0277651 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.027684 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0272212 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0266221 |
| KLHL29 | kelch-like family member 29 | 0.0265864 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0249631 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0247298 |
| HM13 | histocompatibility (minor) 13 | 0.0244154 |
| MORF4L2 | mortality factor 4 like 2 | 0.024306 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.024129 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0240509 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024005 |
| KRT17 | keratin 17, type I | 0.0238451 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0237871 |
| SRPRA | SRP receptor subunit alpha | 0.0237686 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0237313 |
| GOLGA3 | golgin A3 | 0.0236751 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0231448 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0230837 |
| TMF1 | TATA element modulatory factor 1 | 0.0228468 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0227458 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0226401 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0224344 |
| COG5 | component of oligomeric golgi complex 5 | 0.022069 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218505 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0216588 |
| FNIP1 | folliculin interacting protein 1 | 0.0215999 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0215213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.021385 |
| ATXN1 | ataxin 1 | 0.0212018 |
| HKDC1 | hexokinase domain containing 1 | 0.0211649 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0211352 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0207534 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0206497 |
| PHF3 | PHD finger protein 3 | 0.0199093 |
| COPA | coatomer protein complex, subunit alpha | 0.019757 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0196283 |
| MYO5B | myosin VB | 0.0195144 |
| CDK13 | cyclin-dependent kinase 13 | 0.0194582 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0193361 |
| RPL3 | ribosomal protein L3 | 0.0192507 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0192053 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0190929 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0190876 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0190742 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0188597 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0188028 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0187405 |
| ARCN1 | archain 1 | 0.0186721 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0185227 |
| HDLBP | high density lipoprotein binding protein | 0.0185214 |
| PREPL | prolyl endopeptidase-like | 0.0184794 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0181179 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181023 |
| AFDN | afadin, adherens junction formation factor | 0.0180863 |
| SRP54 | signal recognition particle 54kDa | 0.0180111 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0179861 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0178821 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0177662 |
| SET | SET nuclear proto-oncogene | 0.0177333 |
| SEC24D | SEC24 family member D | 0.017707 |
| PGM3 | phosphoglucomutase 3 | 0.0176791 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0174256 |
| TPM3 | tropomyosin 3 | 0.0174218 |
| SPAG9 | sperm associated antigen 9 | 0.0172226 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0170775 |
| SCFD1 | sec1 family domain containing 1 | 0.017 |
| TFG | TRK-fused gene | 0.0168338 |
| FAM13A | family with sequence similarity 13, member A | 0.0167682 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0165688 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0164585 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0163878 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0162902 |
| RPL4 | ribosomal protein L4 | 0.0162648 |
| GAK | cyclin G associated kinase | 0.0162197 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0161066 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0160725 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0159182 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0158635 |
| SETD5 | SET domain containing 5 | 0.015732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216516 |
| TMSB10 | thymosin beta 10 | -0.187032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.116707 |
| B2M | beta-2-microglobulin | -0.113361 |
| RPL35A | ribosomal protein L35a | -0.10582 |
| FTL | ferritin, light polypeptide | -0.0885012 |
| RPS19 | ribosomal protein S19 | -0.0844306 |
| RPS6 | ribosomal protein S6 | -0.076973 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0726165 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0714535 |
| S100A10 | S100 calcium binding protein A10 | -0.070124 |
| RPL23 | ribosomal protein L23 | -0.0686117 |
| RPLP1 | ribosomal protein, large, P1 | -0.0676055 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0656307 |
| PTMA | prothymosin, alpha | -0.064996 |
| RPS21 | ribosomal protein S21 | -0.0600081 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0587237 |
| RPS8 | ribosomal protein S8 | -0.0559971 |
| POTEF | POTE ankyrin domain family, member F | -0.0556196 |
| CLDN4 | claudin 4 | -0.0552217 |
| S100A6 | S100 calcium binding protein A6 | -0.0542392 |
| NDRG1 | N-myc downstream regulated 1 | -0.0539516 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0522046 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0506219 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0500275 |
| S100A9 | S100 calcium binding protein A9 | -0.048186 |
| S100P | S100 calcium binding protein P | -0.0479005 |
| S100A11 | S100 calcium binding protein A11 | -0.0471791 |
| RPL12 | ribosomal protein L12 | -0.0454879 |
| RPL19 | ribosomal protein L19 | -0.0453649 |
| GSTP1 | glutathione S-transferase pi 1 | -0.044446 |
| HLA-A | major histocompatibility complex, class I, A | -0.043762 |
| MUC1 | mucin 1, cell surface associated | -0.043551 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0435046 |
| ANXA2 | annexin A2 | -0.0432854 |
| EMP1 | epithelial membrane protein 1 | -0.0432574 |
| RPL34 | ribosomal protein L34 | -0.0428189 |
| HMGA1 | high mobility group AT-hook 1 | -0.0425251 |
| CLDN7 | claudin 7 | -0.0421332 |
| RPL32 | ribosomal protein L32 | -0.0409293 |
| EPCAM | epithelial cell adhesion molecule | -0.0407752 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0400956 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0397998 |
| PKM | pyruvate kinase, muscle | -0.0392041 |
| RPL28 | ribosomal protein L28 | -0.0390572 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0390048 |
| RPLP2 | ribosomal protein, large, P2 | -0.0388376 |
| KRT19 | keratin 19, type I | -0.038333 |
| ACTN4 | actinin, alpha 4 | -0.0381555 |
| ACTG1 | actin gamma 1 | -0.0377304 |
| RPL9 | ribosomal protein L9 | -0.0376476 |
| RPS3 | ribosomal protein S3 | -0.0372718 |
| RPS25 | ribosomal protein S25 | -0.0368106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0367838 |
| RPS29 | ribosomal protein S29 | -0.0366821 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0364096 |
| RPS11 | ribosomal protein S11 | -0.0362991 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0356798 |
| RPS16 | ribosomal protein S16 | -0.0356097 |
| LCN2 | lipocalin 2 | -0.0354753 |
| RPL11 | ribosomal protein L11 | -0.0353209 |
| PFN1 | profilin 1 | -0.0350455 |
| CST3 | cystatin C | -0.0336988 |
| HLA-B | major histocompatibility complex, class I, B | -0.0331369 |
| RPL35 | ribosomal protein L35 | -0.0330283 |
| RPL38 | ribosomal protein L38 | -0.0325065 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0324538 |
| EGR1 | early growth response 1 | -0.0321074 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0318283 |
| RPL37A | ribosomal protein L37a | -0.0316234 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0314305 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0313293 |
| GPX2 | glutathione peroxidase 2 | -0.0309419 |
| TFF2 | trefoil factor 2 | -0.0302911 |
| RPS27 | ribosomal protein S27 | -0.0300508 |
| LIMA1 | LIM domain and actin binding 1 | -0.0298101 |
| RPLP0 | ribosomal protein, large, P0 | -0.0296493 |
| RPL36 | ribosomal protein L36 | -0.0295662 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0290128 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0288855 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0288113 |
| CBX3 | chromobox homolog 3 | -0.0287086 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0283181 |
| CALR | calreticulin | -0.0282205 |
| ATF5 | activating transcription factor 5 | -0.0281251 |
| RPL27 | ribosomal protein L27 | -0.0278612 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0277116 |
| RPL26 | ribosomal protein L26 | -0.0276702 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0275628 |
| LMNA | lamin A/C | -0.0274802 |
| RPS14 | ribosomal protein S14 | -0.0273896 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0272515 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0272291 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267306 |
| DEK | DEK proto-oncogene | -0.0267152 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0265916 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0265501 |
| RPL31 | ribosomal protein L31 | -0.0262905 |
| EZR | ezrin | -0.0261054 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0259632 |
