| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0784879 |
| CES1 | carboxylesterase 1 | 0.0764882 |
| MCL1 | myeloid cell leukemia 1 | 0.0697459 |
| DTNA | dystrobrevin, alpha | 0.0621414 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0492106 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0472665 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0451068 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0404703 |
| RUNX1 | runt-related transcription factor 1 | 0.0392078 |
| ATP13A3 | ATPase type 13A3 | 0.0389118 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0387488 |
| MKI67 | marker of proliferation Ki-67 | 0.0352923 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0336375 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0333108 |
| GPATCH2L | G patch domain containing 2-like | 0.0289964 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0283554 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0277967 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0275394 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0258156 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0257331 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025498 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0251307 |
| RTN4 | reticulon 4 | 0.0249515 |
| NGLY1 | N-glycanase 1 | 0.0248863 |
| RASA2 | RAS p21 protein activator 2 | 0.0245313 |
| ATP11A | ATPase, class VI, type 11A | 0.0243661 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0241064 |
| WDR26 | WD repeat domain 26 | 0.0233865 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0229251 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.022711 |
| FAM110C | family with sequence similarity 110, member C | 0.0223437 |
| MSN | moesin | 0.0216299 |
| LAMA4 | laminin, alpha 4 | 0.0212424 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0207844 |
| TOP1 | topoisomerase (DNA) I | 0.0205311 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200859 |
| PLEC | plectin | 0.0198824 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0195726 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0193422 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0190635 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0189045 |
| CDCP1 | CUB domain containing protein 1 | 0.0188348 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0183291 |
| CSNK1E | casein kinase 1, epsilon | 0.0182712 |
| YEATS2 | YEATS domain containing 2 | 0.0180853 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0180766 |
| RNF169 | ring finger protein 169 | 0.0176905 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0174636 |
| USP34 | ubiquitin specific peptidase 34 | 0.0174337 |
| JAM3 | junctional adhesion molecule 3 | 0.0168962 |
| RPL3 | ribosomal protein L3 | 0.0168395 |
| PCBP2 | poly(rC) binding protein 2 | 0.0166343 |
| HYOU1 | hypoxia up-regulated 1 | 0.0165631 |
| KLC1 | kinesin light chain 1 | 0.0164912 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0164533 |
| CCNG2 | cyclin G2 | 0.0163645 |
| ZNF638 | zinc finger protein 638 | 0.0163472 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.016346 |
| GSK3B | glycogen synthase kinase 3 beta | 0.015871 |
| BMP6 | bone morphogenetic protein 6 | 0.0157611 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0157055 |
| PRELID2 | PRELI domain containing 2 | 0.0156695 |
| METTL15 | methyltransferase like 15 | 0.0156014 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0154186 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0152892 |
| FRY | furry homolog (Drosophila) | 0.0152503 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0150364 |
| SNX9 | sorting nexin 9 | 0.0146596 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0145112 |
| MYO1B | myosin IB | 0.0144756 |
| PYGL | phosphorylase, glycogen, liver | 0.0144107 |
| RLIM | ring finger protein, LIM domain interacting | 0.0143821 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0142531 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0141249 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0141096 |
| RPL4 | ribosomal protein L4 | 0.0138697 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0138252 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0137678 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0137306 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0136466 |
| RNF149 | ring finger protein 149 | 0.0134422 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0132882 |
| ZNF148 | zinc finger protein 148 | 0.0131804 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0131202 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0131048 |
| WDR49 | WD repeat domain 49 | 0.0129656 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0128981 |
| CUL4A | cullin 4A | 0.0127755 |
| COG5 | component of oligomeric golgi complex 5 | 0.0126273 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0125624 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0125575 |
| TMEM167A | transmembrane protein 167A | 0.0125012 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0124697 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0123545 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0121448 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0121318 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0120134 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0120115 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0119134 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0118816 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.192128 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.190868 |
| ASPH | aspartate beta-hydroxylase | -0.172032 |
| LMO7 | LIM domain 7 | -0.139898 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.121506 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.120306 |
| TMSB10 | thymosin beta 10 | -0.0981993 |
| TXNRD1 | thioredoxin reductase 1 | -0.088518 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0884927 |
| ANXA2 | annexin A2 | -0.0839913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0810874 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0796969 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0752559 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0714602 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0713856 |
| PTMA | prothymosin, alpha | -0.0713517 |
| EGR1 | early growth response 1 | -0.0702474 |
| LDHA | lactate dehydrogenase A | -0.0681445 |
| ACTG1 | actin gamma 1 | -0.066773 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0656501 |
| S100A10 | S100 calcium binding protein A10 | -0.0652563 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0620075 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0617565 |
| RNF213 | ring finger protein 213 | -0.0614377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0549113 |
| NDRG1 | N-myc downstream regulated 1 | -0.054813 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0540378 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0530914 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0530903 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527168 |
| MYOF | myoferlin | -0.0495118 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0489147 |
| CCND1 | cyclin D1 | -0.0483831 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0468075 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0460367 |
| KRT7 | keratin 7, type II | -0.0451262 |
| B2M | beta-2-microglobulin | -0.0449333 |
| KRT18 | keratin 18, type I | -0.0446042 |
| EFNA5 | ephrin-A5 | -0.0423374 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.042291 |
| CST3 | cystatin C | -0.0416384 |
| EGFR | epidermal growth factor receptor | -0.0410288 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0408973 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0389255 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0387537 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.038673 |
| STC1 | stanniocalcin 1 | -0.0386589 |
| ENO1 | enolase 1, (alpha) | -0.0363847 |
| AHNAK | AHNAK nucleoprotein | -0.0363627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360245 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0354818 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0350889 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0347241 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0345797 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0344775 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0337985 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0334171 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0333429 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0332694 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.033253 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.03298 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0329054 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0328192 |
| GNAS | GNAS complex locus | -0.0327736 |
| TRIM56 | tripartite motif containing 56 | -0.0321373 |
| PKM | pyruvate kinase, muscle | -0.0320688 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0315964 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.031596 |
| FTL | ferritin, light polypeptide | -0.0306496 |
| H1-0 | H1.0 linker histone | -0.0306023 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0305066 |
| TPM4 | tropomyosin 4 | -0.0304613 |
| CPE | carboxypeptidase E | -0.0300903 |
| FAM13A | family with sequence similarity 13, member A | -0.0300089 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0299816 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0291498 |
| DSPP | dentin sialophosphoprotein | -0.0287011 |
| PARD3 | par-3 family cell polarity regulator | -0.0286284 |
| S100A6 | S100 calcium binding protein A6 | -0.0284902 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0279388 |
| PDE8A | phosphodiesterase 8A | -0.0279285 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0279257 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0278678 |
| CAV2 | caveolin 2 | -0.0278548 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0278302 |
| EZR | ezrin | -0.0277837 |
| SQSTM1 | sequestosome 1 | -0.0276185 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.026671 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0263274 |
| SP100 | SP100 nuclear antigen | -0.0263205 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0261946 |
| IER3 | immediate early response 3 | -0.0261787 |
| CUX1 | cut-like homeobox 1 | -0.026169 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0261567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0260687 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0253881 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0253615 |
| DSG2 | desmoglein 2 | -0.0251804 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024918 |
| S100A11 | S100 calcium binding protein A11 | -0.0245869 |
