| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.15895 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.133119 |
| SMAD3 | SMAD family member 3 | 0.0846911 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0835022 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0812302 |
| FN1 | fibronectin 1 | 0.079703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0662741 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0605951 |
| TMSB10 | thymosin beta 10 | 0.0603828 |
| HMGA2 | high mobility group AT-hook 2 | 0.0594799 |
| FAM20C | family with sequence similarity 20, member C | 0.0583242 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0565295 |
| LOX | lysyl oxidase | 0.0562633 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0553876 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0531777 |
| CDH13 | cadherin 13 | 0.053112 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0526454 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0503695 |
| USP34 | ubiquitin specific peptidase 34 | 0.0501184 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0490448 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0453968 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0444239 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0443615 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0441801 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0432718 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0427456 |
| AHNAK | AHNAK nucleoprotein | 0.0423886 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0421409 |
| RAI14 | retinoic acid induced 14 | 0.0420339 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0420187 |
| CD44 | CD44 molecule (Indian blood group) | 0.0412948 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0405645 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0405368 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0402481 |
| EGFR | epidermal growth factor receptor | 0.0399482 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0397593 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0393502 |
| VIM | vimentin | 0.0390592 |
| PYGL | phosphorylase, glycogen, liver | 0.0389755 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0389312 |
| ANGPTL4 | angiopoietin-like 4 | 0.0383609 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0379055 |
| ENO1 | enolase 1, (alpha) | 0.0375923 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0372012 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0363772 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0360355 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0359821 |
| STC1 | stanniocalcin 1 | 0.0358525 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0355493 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0351657 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.035029 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0348523 |
| HDLBP | high density lipoprotein binding protein | 0.0347976 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.034519 |
| NAV2 | neuron navigator 2 | 0.0342676 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0341859 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0337013 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0335768 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0333843 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0333567 |
| GLCCI1 | glucocorticoid induced 1 | 0.0332794 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0328378 |
| TMSB4X | thymosin beta 4, X-linked | 0.0320306 |
| PGK1 | phosphoglycerate kinase 1 | 0.03184 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0317723 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0314012 |
| FMNL2 | formin-like 2 | 0.0312994 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0312289 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0311314 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0305526 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0305338 |
| SEPTIN2 | septin 2 | 0.0297195 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0294973 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0294951 |
| MYO9A | myosin IXA | 0.0292424 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0292248 |
| NGLY1 | N-glycanase 1 | 0.0291657 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0289272 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0288636 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0285664 |
| CPNE1 | copine I | 0.0285604 |
| ATP13A3 | ATPase type 13A3 | 0.0278094 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0272251 |
| ADD3 | adducin 3 (gamma) | 0.0272127 |
| SEPTIN9 | septin 9 | 0.0271557 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0271478 |
| FLNB | filamin B, beta | 0.0269947 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0268279 |
| HDAC9 | histone deacetylase 9 | 0.0267095 |
| FBN1 | fibrillin 1 | 0.0266193 |
| GOLGA3 | golgin A3 | 0.0264628 |
| NTN4 | netrin 4 | 0.0263595 |
| RPL32 | ribosomal protein L32 | 0.0263008 |
| SSH2 | slingshot protein phosphatase 2 | 0.0261784 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0259324 |
| CANX | calnexin | 0.0258667 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258625 |
| ECE1 | endothelin converting enzyme 1 | 0.0256472 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0253257 |
| OXSR1 | oxidative stress responsive 1 | 0.0251366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | -0.10718 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0963928 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0719373 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0673379 |
| NDRG1 | N-myc downstream regulated 1 | -0.0664872 |
| GPC6 | glypican 6 | -0.0652355 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0651749 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0610351 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0552295 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0467963 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0446979 |
| POTEF | POTE ankyrin domain family, member F | -0.0434724 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0421708 |
| CCNL1 | cyclin L1 | -0.041862 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0413846 |
| HMGA1 | high mobility group AT-hook 1 | -0.0405818 |
| EGR1 | early growth response 1 | -0.0394053 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0359043 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0354085 |
| YBX1 | Y box binding protein 1 | -0.0353814 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0336327 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0322771 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0315294 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0313911 |
| ARF4 | ADP-ribosylation factor 4 | -0.0313863 |
| ZNF292 | zinc finger protein 292 | -0.0307416 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0302987 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0293341 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0292641 |
| TBK1 | TANK-binding kinase 1 | -0.0284035 |
| HELZ | helicase with zinc finger | -0.0278622 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0278192 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0276988 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0267068 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0258501 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0255253 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0254386 |
| FAM13A | family with sequence similarity 13, member A | -0.0247616 |
| TBC1D5 | TBC1 domain family, member 5 | -0.024268 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0235978 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0232155 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0230908 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0227281 |
| MX1 | MX dynamin-like GTPase 1 | -0.021883 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0218423 |
| RBM39 | RNA binding motif protein 39 | -0.0215097 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0211633 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0210084 |
| TAPBP | TAP binding protein (tapasin) | -0.0209113 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0208698 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0208097 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0207969 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0206753 |
| TPM3 | tropomyosin 3 | -0.0205854 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0201723 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0201261 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0199381 |
| TNNC1 | troponin C type 1 (slow) | -0.0198972 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0197293 |
| METTL15 | methyltransferase like 15 | -0.0196794 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0196504 |
| KLHL15 | kelch-like family member 15 | -0.0195511 |
| NRG1 | neuregulin 1 | -0.0194178 |
| ANXA1 | annexin A1 | -0.0192177 |
| IFI44L | interferon-induced protein 44-like | -0.0190447 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0190439 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0190357 |
| GTF2B | general transcription factor IIB | -0.0188802 |
| BRD2 | bromodomain containing 2 | -0.0188318 |
| INTS1 | integrator complex subunit 1 | -0.0187363 |
| NBAS | neuroblastoma amplified sequence | -0.0186376 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0183522 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0182946 |
| PTEN | phosphatase and tensin homolog | -0.0181343 |
| PHF21A | PHD finger protein 21A | -0.018132 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0179928 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0176669 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0176464 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0174079 |
| ANXA5 | annexin A5 | -0.0171886 |
| NUP58 | nucleoporin 58 | -0.0170806 |
| TXNRD1 | thioredoxin reductase 1 | -0.0170029 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0169508 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0165677 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0165181 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0163178 |
| FBXO32 | F-box protein 32 | -0.0161603 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0161368 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0161165 |
| PNN | pinin, desmosome associated protein | -0.0161025 |
| RPS6 | ribosomal protein S6 | -0.015972 |
| CENPF | centromere protein F, 350/400kDa | -0.0158597 |
| SYAP1 | synapse associated protein 1 | -0.0157145 |
| TRIM25 | tripartite motif containing 25 | -0.0152934 |
| COG5 | component of oligomeric golgi complex 5 | -0.0151961 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0150555 |
| FOSL1 | FOS-like antigen 1 | -0.0149235 |
| SAP30BP | SAP30 binding protein | -0.0148865 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0145829 |
| MEF2D | myocyte enhancer factor 2D | -0.0144808 |
