| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0883116 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0850924 |
| LMO7 | LIM domain 7 | 0.0708086 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0672039 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0617509 |
| GOLGA4 | golgin A4 | 0.0594486 |
| LAMC2 | laminin, gamma 2 | 0.0582383 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0569715 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0525784 |
| FAM13A | family with sequence similarity 13, member A | 0.051369 |
| GPC6 | glypican 6 | 0.0426662 |
| OXR1 | oxidation resistance 1 | 0.0401234 |
| USP3 | ubiquitin specific peptidase 3 | 0.0381647 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0367084 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0364493 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0353723 |
| SUCO | SUN domain containing ossification factor | 0.0353386 |
| TPR | translocated promoter region, nuclear basket protein | 0.0346472 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0340909 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0340477 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0340387 |
| RPL26 | ribosomal protein L26 | 0.0338773 |
| VGLL3 | vestigial-like family member 3 | 0.0338584 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0334896 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0331126 |
| YTHDC1 | YTH domain containing 1 | 0.0312847 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0307893 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0307877 |
| TMF1 | TATA element modulatory factor 1 | 0.0307362 |
| MRTFA | myocardin related transcription factor A | 0.0305269 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0304063 |
| RBM47 | RNA binding motif protein 47 | 0.0301762 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0298391 |
| MATR3 | matrin 3 | 0.0297335 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296835 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0295175 |
| PTMA | prothymosin, alpha | 0.0293387 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0292826 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.028602 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0284288 |
| CMIP | c-Maf inducing protein | 0.0281133 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.0280159 |
| YME1L1 | YME1-like 1 ATPase | 0.0276579 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0273967 |
| XPO1 | exportin 1 | 0.0273135 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0272667 |
| CTBP2 | C-terminal binding protein 2 | 0.027215 |
| FOXO3 | forkhead box O3 | 0.0265417 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0263175 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0261803 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0260875 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0259892 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0256386 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0252436 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0249361 |
| ARGLU1 | arginine and glutamate rich 1 | 0.024544 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0243818 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.0243182 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0241182 |
| RIOK3 | RIO kinase 3 | 0.0240405 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0236896 |
| SGMS2 | sphingomyelin synthase 2 | 0.02365 |
| PRELID2 | PRELI domain containing 2 | 0.0235056 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0233921 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0232731 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0232609 |
| NUP58 | nucleoporin 58 | 0.0230819 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0230374 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0229025 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0228916 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0228862 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0228845 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0226347 |
| POLK | polymerase (DNA directed) kappa | 0.0222998 |
| VGLL4 | vestigial-like family member 4 | 0.0222828 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0222039 |
| SVIL | supervillin | 0.0220786 |
| CUL3 | cullin 3 | 0.0220419 |
| ADIPOR2 | adiponectin receptor 2 | 0.0219804 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0218665 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218567 |
| ADM | adrenomedullin | 0.0217797 |
| TMEM41B | transmembrane protein 41B | 0.0217458 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0217071 |
| SSH2 | slingshot protein phosphatase 2 | 0.0215826 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0215101 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 0.0214658 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0214645 |
| TUT7 | terminal uridylyl transferase 7 | 0.0213646 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0213561 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0212731 |
| RREB1 | ras responsive element binding protein 1 | 0.0212722 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0210822 |
| CDC27 | cell division cycle 27 | 0.0210527 |
| SQSTM1 | sequestosome 1 | 0.0210418 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0209755 |
| MYO6 | myosin VI | 0.0208225 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0207882 |
| PCDHB16 | protocadherin beta 16 | 0.0207433 |
| TXNRD1 | thioredoxin reductase 1 | 0.020679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.141319 |
| NDRG1 | N-myc downstream regulated 1 | -0.118756 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110717 |
| IGF2 | insulin-like growth factor 2 | -0.104502 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0714683 |
| KYNU | kynureninase | -0.0691713 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0659387 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0651368 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.063852 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0622664 |
| KRT17 | keratin 17, type I | -0.0618335 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0615339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0551848 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0533446 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0512988 |
| STC1 | stanniocalcin 1 | -0.0506951 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0479327 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.047284 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0467401 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0457064 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0450756 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0428775 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0425416 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0424699 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0422518 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0394806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0394205 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0391271 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0390729 |
| DST | dystonin | -0.0377808 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.037197 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0371598 |
| OGA | O-GlcNAcase | -0.0371512 |
| CDH13 | cadherin 13 | -0.0363439 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0357225 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0353484 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0352759 |
| RND3 | Rho family GTPase 3 | -0.0351456 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0349021 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0346273 |
| OSMR | oncostatin M receptor | -0.0340957 |
| RIGI | RNA sensor RIG-I | -0.0338993 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0338285 |
| ENO1 | enolase 1, (alpha) | -0.0333346 |
| MXD1 | MAX dimerization protein 1 | -0.0331247 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.032822 |
| PKM | pyruvate kinase, muscle | -0.032313 |
| TJP1 | tight junction protein 1 | -0.0319114 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0312945 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0311174 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0310983 |
| SP100 | SP100 nuclear antigen | -0.0308717 |
| PRKCA | protein kinase C, alpha | -0.0307871 |
| HMBOX1 | homeobox containing 1 | -0.030761 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0307341 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0305763 |
| ASPH | aspartate beta-hydroxylase | -0.0301856 |
| TCF12 | transcription factor 12 | -0.0298513 |
| FLNB | filamin B, beta | -0.0297433 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0294224 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0287418 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.028646 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0281895 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0279581 |
| VIM | vimentin | -0.0278287 |
| RPS6 | ribosomal protein S6 | -0.0277575 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0275267 |
| RPL12 | ribosomal protein L12 | -0.0273866 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0272999 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0271355 |
| IL6ST | interleukin 6 signal transducer | -0.0270453 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0269656 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0269229 |
| RPL5 | ribosomal protein L5 | -0.0265048 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0263773 |
| EZR | ezrin | -0.0259667 |
| CCDC88A | coiled-coil domain containing 88A | -0.0255337 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0252061 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0246397 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0246024 |
| SASH1 | SAM and SH3 domain containing 1 | -0.02452 |
| RPL28 | ribosomal protein L28 | -0.0244814 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0244733 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242318 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0242309 |
| ATXN1 | ataxin 1 | -0.0241018 |
| CANX | calnexin | -0.0239448 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238136 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0236214 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.023565 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0234428 |
| UBXN4 | UBX domain protein 4 | -0.0234392 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0234328 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0233571 |
| LDHA | lactate dehydrogenase A | -0.0233189 |
| PARD3 | par-3 family cell polarity regulator | -0.0232858 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0232673 |
| SBF2 | SET binding factor 2 | -0.0232149 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0231253 |
| CCNI | cyclin I | -0.0230105 |
