| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lopinavir_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0688546 |
| PLEC | plectin | 0.058737 |
| FN1 | fibronectin 1 | 0.0560263 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.046403 |
| MYO5B | myosin VB | 0.0407443 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0398223 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0397536 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0395821 |
| DTNA | dystrobrevin, alpha | 0.038906 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0317126 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0276476 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0265693 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0261098 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253191 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0246017 |
| LAMC2 | laminin, gamma 2 | 0.024403 |
| MYO6 | myosin VI | 0.0231746 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0230607 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0226586 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0224362 |
| RPSA | ribosomal protein SA | 0.022014 |
| FAM3C | family with sequence similarity 3, member C | 0.0220107 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0217178 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0214974 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.02082 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0203967 |
| AFDN | afadin, adherens junction formation factor | 0.0201092 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0198134 |
| ANXA1 | annexin A1 | 0.0197817 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.019625 |
| ATP13A3 | ATPase type 13A3 | 0.0195221 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184902 |
| RPL4 | ribosomal protein L4 | 0.0181844 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0178114 |
| SNX9 | sorting nexin 9 | 0.0178081 |
| ABI1 | abl-interactor 1 | 0.0177441 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0175904 |
| RPL3 | ribosomal protein L3 | 0.0174102 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0171929 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0168662 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0166458 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0163449 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0160103 |
| ERBIN | erbb2 interacting protein | 0.0160006 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0159644 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0159633 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0159184 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0159067 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0158092 |
| NCKAP1 | NCK-associated protein 1 | 0.0155846 |
| NEK7 | NIMA-related kinase 7 | 0.0154196 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0153083 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0152571 |
| YTHDC1 | YTH domain containing 1 | 0.0151977 |
| DUSP10 | dual specificity phosphatase 10 | 0.0149391 |
| FLNA | filamin A, alpha | 0.0148837 |
| NAV2 | neuron navigator 2 | 0.0147469 |
| EFNA5 | ephrin-A5 | 0.0147241 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.014713 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0144308 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0142847 |
| OCLN | occludin | 0.0142439 |
| KLC1 | kinesin light chain 1 | 0.0141562 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0141486 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0141034 |
| RCOR1 | REST corepressor 1 | 0.0140664 |
| MSN | moesin | 0.013687 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0134933 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0134397 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0132796 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.012927 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0129268 |
| CDC73 | cell division cycle 73 | 0.0124576 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0124182 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0123925 |
| H1-4 | H1.4 linker histone, cluster member | 0.0123374 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0122117 |
| RASA2 | RAS p21 protein activator 2 | 0.0120013 |
| VGLL3 | vestigial-like family member 3 | 0.0119918 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0118049 |
| BCL2L1 | BCL2-like 1 | 0.0117351 |
| ANXA11 | annexin A11 | 0.0116364 |
| LTA4H | leukotriene A4 hydrolase | 0.0116125 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0115538 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0115134 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.011367 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0113295 |
| NUMB | numb homolog (Drosophila) | 0.0113121 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0113009 |
| IRF6 | interferon regulatory factor 6 | 0.0111412 |
| TJP1 | tight junction protein 1 | 0.0111285 |
| SNX4 | sorting nexin 4 | 0.0110492 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0110397 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0109051 |
| SDC4 | syndecan 4 | 0.0108891 |
| UBQLN1 | ubiquilin 1 | 0.0107647 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0106813 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0106701 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0106566 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0106442 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236135 |
| PTMA | prothymosin, alpha | -0.202634 |
| FTL | ferritin, light polypeptide | -0.186182 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.155946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.122079 |
| NDRG1 | N-myc downstream regulated 1 | -0.112643 |
| POTEF | POTE ankyrin domain family, member F | -0.106898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.101734 |
| ACTG1 | actin gamma 1 | -0.0892252 |
| TMSB10 | thymosin beta 10 | -0.0891203 |
| S100A6 | S100 calcium binding protein A6 | -0.0857529 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0825942 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0811214 |
| HMGA1 | high mobility group AT-hook 1 | -0.079479 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.073514 |
| SQSTM1 | sequestosome 1 | -0.0670797 |
| RPLP1 | ribosomal protein, large, P1 | -0.0666823 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0629383 |
| RPL35A | ribosomal protein L35a | -0.0614549 |
| S100A10 | S100 calcium binding protein A10 | -0.0605015 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0593131 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0593059 |
| RPS6 | ribosomal protein S6 | -0.0588952 |
| ENO1 | enolase 1, (alpha) | -0.0583111 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0567269 |
| FAM13A | family with sequence similarity 13, member A | -0.0560607 |
| RPS8 | ribosomal protein S8 | -0.0559958 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0520719 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0509639 |
| LDHA | lactate dehydrogenase A | -0.0501279 |
| TPM4 | tropomyosin 4 | -0.0493473 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0493389 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0488299 |
| RPL8 | ribosomal protein L8 | -0.048151 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0471842 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0446623 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0444723 |
| ANXA2 | annexin A2 | -0.0435562 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0433749 |
| GNAS | GNAS complex locus | -0.0430353 |
| CSTB | cystatin B (stefin B) | -0.0428473 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0417769 |
| RPL34 | ribosomal protein L34 | -0.0409159 |
| TMSB4X | thymosin beta 4, X-linked | -0.0409048 |
| RPS19 | ribosomal protein S19 | -0.0404627 |
| RPLP0 | ribosomal protein, large, P0 | -0.0401417 |
| MT2A | metallothionein 2A | -0.0400359 |
| CCND1 | cyclin D1 | -0.0394432 |
| RPS3 | ribosomal protein S3 | -0.0394182 |
| RACK1 | receptor for activated C kinase 1 | -0.0393738 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0393299 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0392786 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0389223 |
| VIM | vimentin | -0.0388062 |
| RPS13 | ribosomal protein S13 | -0.0384861 |
| RPS29 | ribosomal protein S29 | -0.0383392 |
| HLA-A | major histocompatibility complex, class I, A | -0.0383362 |
| DSTN | destrin (actin depolymerizing factor) | -0.0377331 |
| PKM | pyruvate kinase, muscle | -0.0377002 |
| FAM162A | family with sequence similarity 162, member A | -0.03711 |
| RPL37A | ribosomal protein L37a | -0.0366047 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0365065 |
| RPS23 | ribosomal protein S23 | -0.0351279 |
| RPLP2 | ribosomal protein, large, P2 | -0.0346112 |
| RPL12 | ribosomal protein L12 | -0.0344944 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0344101 |
| CANX | calnexin | -0.0341282 |
| FBXO32 | F-box protein 32 | -0.0334656 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0331641 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.032628 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0324055 |
| S100A9 | S100 calcium binding protein A9 | -0.0322271 |
| KRT7 | keratin 7, type II | -0.0320991 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0315172 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0314782 |
| YBX1 | Y box binding protein 1 | -0.0310294 |
| LMNA | lamin A/C | -0.0307229 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0304666 |
| RPL9 | ribosomal protein L9 | -0.0302519 |
| ZNF292 | zinc finger protein 292 | -0.0302231 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0301009 |
| RPL30 | ribosomal protein L30 | -0.0296966 |
| RPS14 | ribosomal protein S14 | -0.0291154 |
| EPCAM | epithelial cell adhesion molecule | -0.028991 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0288499 |
| B2M | beta-2-microglobulin | -0.028848 |
| RPL32 | ribosomal protein L32 | -0.0288325 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0286855 |
| PGK1 | phosphoglycerate kinase 1 | -0.0285269 |
| WASF2 | WAS protein family, member 2 | -0.0284191 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0283981 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0282524 |
| HLA-B | major histocompatibility complex, class I, B | -0.0280811 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0280038 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0278818 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0278264 |
| RPS27 | ribosomal protein S27 | -0.0277612 |
| RPL23 | ribosomal protein L23 | -0.0276968 |
| KRT19 | keratin 19, type I | -0.0270877 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0268185 |
