| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lopinavir perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lopinavir_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.164343 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.152929 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0888018 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.077097 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0694348 |
| ARRDC3 | arrestin domain containing 3 | 0.0604004 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0517381 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0494616 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0450138 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0437501 |
| PGK1 | phosphoglycerate kinase 1 | 0.0415992 |
| MKI67 | marker of proliferation Ki-67 | 0.0397344 |
| SDC4 | syndecan 4 | 0.0381419 |
| RTN4 | reticulon 4 | 0.0380197 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.037648 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0364911 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0354684 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347417 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0335742 |
| OGA | O-GlcNAcase | 0.0324637 |
| CENPF | centromere protein F, 350/400kDa | 0.032387 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0321568 |
| ANLN | anillin, actin binding protein | 0.0312165 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0310071 |
| CEP250 | centrosomal protein 250kDa | 0.0301471 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0297032 |
| KIF4A | kinesin family member 4A | 0.0296144 |
| SMAD3 | SMAD family member 3 | 0.0295866 |
| KLF6 | Kruppel-like factor 6 | 0.0287372 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0283794 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0278459 |
| MYOF | myoferlin | 0.0272524 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0266713 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0262941 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0255901 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0253708 |
| DUSP5 | dual specificity phosphatase 5 | 0.0251729 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249208 |
| TPX2 | TPX2, microtubule-associated | 0.0243665 |
| SERINC1 | serine incorporator 1 | 0.0240628 |
| APP | amyloid beta (A4) precursor protein | 0.0239676 |
| CEP95 | centrosomal protein 95kDa | 0.0235674 |
| CAVIN1 | caveolae associated protein 1 | 0.0233365 |
| TGFB2 | transforming growth factor, beta 2 | 0.0231697 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231038 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0222605 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0221669 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.021997 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0215906 |
| DIAPH3 | diaphanous-related formin 3 | 0.0214224 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0212583 |
| TMSB4X | thymosin beta 4, X-linked | 0.0212227 |
| PRR11 | proline rich 11 | 0.0210377 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0207716 |
| XPO1 | exportin 1 | 0.0207125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0205982 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0205812 |
| EZR | ezrin | 0.0201911 |
| ATRN | attractin | 0.0201222 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0198753 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0196909 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0195392 |
| YBX3 | Y box binding protein 3 | 0.0191061 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0190888 |
| AFDN | afadin, adherens junction formation factor | 0.0190743 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0190448 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0188281 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0185925 |
| PLPP6 | phospholipid phosphatase 6 | 0.0185922 |
| YTHDC1 | YTH domain containing 1 | 0.0181657 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0181284 |
| ZNF654 | zinc finger protein 654 | 0.017881 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0177932 |
| TPI1 | triosephosphate isomerase 1 | 0.0176929 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0176362 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0175991 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0172977 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0172933 |
| LMO7 | LIM domain 7 | 0.016986 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0168013 |
| KIAA1958 | KIAA1958 | 0.0167272 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0166139 |
| RASA2 | RAS p21 protein activator 2 | 0.0164243 |
| NKTR | natural killer cell triggering receptor | 0.0163002 |
| USP37 | ubiquitin specific peptidase 37 | 0.0162596 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0161947 |
| CENPE | centromere protein E, 312kDa | 0.0161243 |
| NGLY1 | N-glycanase 1 | 0.0160605 |
| AHR | aryl hydrocarbon receptor | 0.0160595 |
| FNBP4 | formin binding protein 4 | 0.01587 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0157828 |
| PFKP | phosphofructokinase, platelet | 0.0157827 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0157683 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0155955 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0155817 |
| WAPL | WAPL cohesin release factor | 0.01556 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0155228 |
| TXNIP | thioredoxin interacting protein | 0.0153172 |
| RAI1 | retinoic acid induced 1 | 0.0152484 |
| RPS27A | ribosomal protein S27a | 0.0151971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.168935 |
| GLIS3 | GLIS family zinc finger 3 | -0.156888 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.13851 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.127584 |
| VIM | vimentin | -0.122179 |
| CDH13 | cadherin 13 | -0.119404 |
| HMGA2 | high mobility group AT-hook 2 | -0.118717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.104934 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0889387 |
| FRMD4A | FERM domain containing 4A | -0.0831936 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0741458 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0730223 |
| VCAN | versican | -0.0706867 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0700411 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0642838 |
| DST | dystonin | -0.0637356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0636121 |
| VCL | vinculin | -0.0633908 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0591656 |
| CD44 | CD44 molecule (Indian blood group) | -0.0580668 |
| NAV1 | neuron navigator 1 | -0.056119 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0557551 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0551003 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0547735 |
| NDRG1 | N-myc downstream regulated 1 | -0.0539097 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.051225 |
| NABP1 | nucleic acid binding protein 1 | -0.0509985 |
| TPM1 | tropomyosin 1 (alpha) | -0.0508061 |
| AFF3 | AF4/FMR2 family, member 3 | -0.050656 |
| TMEM132D | transmembrane protein 132D | -0.0504736 |
| DIAPH2 | diaphanous-related formin 2 | -0.0502461 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0497156 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0493038 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0485695 |
| EGFR | epidermal growth factor receptor | -0.0481669 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.047081 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0469135 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0467956 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0461973 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0460168 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0458728 |
| EGR1 | early growth response 1 | -0.0452161 |
| SQSTM1 | sequestosome 1 | -0.0451221 |
| INTS6 | integrator complex subunit 6 | -0.0447357 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.04438 |
| VEGFA | vascular endothelial growth factor A | -0.0440628 |
| RPS6 | ribosomal protein S6 | -0.0432516 |
| HDAC9 | histone deacetylase 9 | -0.0430077 |
| PDE10A | phosphodiesterase 10A | -0.0423061 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0420413 |
| COL5A1 | collagen, type V, alpha 1 | -0.0417194 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0411834 |
| CADM1 | cell adhesion molecule 1 | -0.0402171 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0397791 |
| RND3 | Rho family GTPase 3 | -0.0396618 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0395737 |
| C3 | complement component 3 | -0.0394181 |
| FTL | ferritin, light polypeptide | -0.0392677 |
| ATXN1 | ataxin 1 | -0.0382707 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0378166 |
| CTSD | cathepsin D | -0.0371467 |
| LDHA | lactate dehydrogenase A | -0.036342 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0363374 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0354353 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0353194 |
| PLIN2 | perilipin 2 | -0.0352524 |
| TAPBP | TAP binding protein (tapasin) | -0.0351651 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0348926 |
| HMGA1 | high mobility group AT-hook 1 | -0.0348403 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0348063 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0344066 |
| TPM4 | tropomyosin 4 | -0.0342243 |
| AUTS2 | autism susceptibility candidate 2 | -0.0342039 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0341297 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0339819 |
| EFNA5 | ephrin-A5 | -0.0339101 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0338382 |
| HLA-A | major histocompatibility complex, class I, A | -0.0333538 |
| CALR | calreticulin | -0.0327808 |
| BICC1 | BicC family RNA binding protein 1 | -0.0325593 |
| QKI | QKI, KH domain containing, RNA binding | -0.0324918 |
| IER3 | immediate early response 3 | -0.0323574 |
| TENM2 | teneurin transmembrane protein 2 | -0.0321107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318748 |
| ASPH | aspartate beta-hydroxylase | -0.0317179 |
| LOX | lysyl oxidase | -0.0315284 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0315103 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0310959 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0310305 |
| EXOC4 | exocyst complex component 4 | -0.0304547 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0303147 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303068 |
| RNF213 | ring finger protein 213 | -0.0298294 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0294392 |
| NRP1 | neuropilin 1 | -0.029404 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0289268 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0288659 |
| BNC2 | basonuclin 2 | -0.0283519 |
| COL1A2 | collagen, type I, alpha 2 | -0.0283193 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0282109 |
