| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.107742 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0581412 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0571016 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0534269 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0514062 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0492121 |
| APP | amyloid beta (A4) precursor protein | 0.0459918 |
| COL3A1 | collagen, type III, alpha 1 | 0.045548 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0445993 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0437165 |
| TMSB4X | thymosin beta 4, X-linked | 0.0434759 |
| ATP13A3 | ATPase type 13A3 | 0.0429869 |
| MT2A | metallothionein 2A | 0.0401681 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0394646 |
| HLA-B | major histocompatibility complex, class I, B | 0.0388744 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0384451 |
| RTN4 | reticulon 4 | 0.0383176 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0378825 |
| TPM3 | tropomyosin 3 | 0.0367917 |
| PLAT | plasminogen activator, tissue | 0.0348018 |
| NAV1 | neuron navigator 1 | 0.0331411 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0317464 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0300638 |
| MTSS1 | metastasis suppressor 1 | 0.029438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0280133 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.027258 |
| PTMA | prothymosin, alpha | 0.0268704 |
| B2M | beta-2-microglobulin | 0.0267512 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0265197 |
| ZNF292 | zinc finger protein 292 | 0.0257594 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0255017 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0254947 |
| AUTS2 | autism susceptibility candidate 2 | 0.025337 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0251615 |
| GOLGA4 | golgin A4 | 0.024862 |
| RLF | rearranged L-myc fusion | 0.0248278 |
| TXNRD1 | thioredoxin reductase 1 | 0.0243781 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0242011 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0234796 |
| HLA-C | major histocompatibility complex, class I, C | 0.0232281 |
| OGA | O-GlcNAcase | 0.0228342 |
| AFAP1 | actin filament associated protein 1 | 0.0227751 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0226789 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0225604 |
| RBM39 | RNA binding motif protein 39 | 0.022489 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0224224 |
| PLEC | plectin | 0.0222816 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0221404 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0220623 |
| TUSC3 | tumor suppressor candidate 3 | 0.0220539 |
| DENND5A | DENN/MADD domain containing 5A | 0.0220444 |
| PRKD3 | protein kinase D3 | 0.0218136 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0211936 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0211477 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0211411 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0211004 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0209999 |
| EPN2 | epsin 2 | 0.0209861 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.020795 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0207741 |
| TSPAN9 | tetraspanin 9 | 0.0207586 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0207346 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0206776 |
| WTAP | Wilms tumor 1 associated protein | 0.0206101 |
| COL1A2 | collagen, type I, alpha 2 | 0.0204552 |
| MRTFA | myocardin related transcription factor A | 0.0204301 |
| USP34 | ubiquitin specific peptidase 34 | 0.0201355 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0200179 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0197795 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0197585 |
| RRBP1 | ribosome binding protein 1 | 0.019565 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0193722 |
| HLA-E | major histocompatibility complex, class I, E | 0.0193585 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0193566 |
| STX1A | syntaxin 1A (brain) | 0.0192386 |
| STC1 | stanniocalcin 1 | 0.0191518 |
| USP47 | ubiquitin specific peptidase 47 | 0.0190896 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0190444 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0190028 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0188944 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0188781 |
| FBN1 | fibrillin 1 | 0.0188223 |
| RPL37A | ribosomal protein L37a | 0.0187568 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0187033 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0186692 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0185921 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0182471 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0182432 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0181745 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0181101 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0179081 |
| S100A4 | S100 calcium binding protein A4 | 0.0179044 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0178174 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0177648 |
| VCL | vinculin | 0.0177284 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0177133 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.0176929 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.017686 |
| GPC6 | glypican 6 | 0.0175532 |
| SECISBP2L | SECIS binding protein 2-like | 0.0175317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.172177 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.155446 |
| NDRG1 | N-myc downstream regulated 1 | -0.132398 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.127366 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.11612 |
| LOX | lysyl oxidase | -0.107493 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.107253 |
| COL5A1 | collagen, type V, alpha 1 | -0.101039 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0919659 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0903905 |
| PODXL | podocalyxin-like | -0.0829759 |
| CANX | calnexin | -0.0824341 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0821494 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0755606 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0695166 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0690125 |
| CDH13 | cadherin 13 | -0.066872 |
| EGFR | epidermal growth factor receptor | -0.0654615 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.063439 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0589242 |
| CD109 | CD109 molecule | -0.0579828 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0572872 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0572368 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0562211 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0553304 |
| PRELID2 | PRELI domain containing 2 | -0.0546432 |
| COL5A2 | collagen, type V, alpha 2 | -0.0539616 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0525184 |
| PKM | pyruvate kinase, muscle | -0.0486441 |
| CENPF | centromere protein F, 350/400kDa | -0.0484195 |
| RIGI | RNA sensor RIG-I | -0.0478955 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0475393 |
| SP100 | SP100 nuclear antigen | -0.0470095 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0465932 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0465262 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0462067 |
| INTS6 | integrator complex subunit 6 | -0.045423 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0449321 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0439562 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0434 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0427106 |
| TAGLN2 | transgelin 2 | -0.0416439 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0412974 |
| MYADM | myeloid-associated differentiation marker | -0.0405709 |
| MAP1B | microtubule-associated protein 1B | -0.0403594 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0394883 |
| AHNAK | AHNAK nucleoprotein | -0.039476 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0393697 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0388834 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0378004 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0377911 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0377821 |
| MYOF | myoferlin | -0.03772 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0351839 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0351557 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0350801 |
| TENM3 | teneurin transmembrane protein 3 | -0.0349624 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0349444 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0347714 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0334652 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.032929 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0325578 |
| VIM | vimentin | -0.0319337 |
| LDHA | lactate dehydrogenase A | -0.0315811 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0315359 |
| ENO1 | enolase 1, (alpha) | -0.0312425 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0310129 |
| FNIP1 | folliculin interacting protein 1 | -0.0308951 |
| FSTL1 | follistatin-like 1 | -0.0306682 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0304175 |
| L1CAM | L1 cell adhesion molecule | -0.0301237 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0298984 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0298295 |
| POTEF | POTE ankyrin domain family, member F | -0.0297054 |
| CUX1 | cut-like homeobox 1 | -0.0294103 |
| MMP12 | matrix metallopeptidase 12 | -0.0290285 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0289667 |
| CCND1 | cyclin D1 | -0.0288232 |
| CALU | calumenin | -0.0286154 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0281386 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0281159 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0280043 |
| RASAL2 | RAS protein activator like 2 | -0.0277471 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0276391 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0274206 |
| FN1 | fibronectin 1 | -0.0273816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0272815 |
| DCLK2 | doublecortin-like kinase 2 | -0.0271605 |
| SRPK2 | SRSF protein kinase 2 | -0.0270736 |
| EFNA5 | ephrin-A5 | -0.0270681 |
| PFN1 | profilin 1 | -0.0267327 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0266491 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0266307 |
| JAZF1 | JAZF zinc finger 1 | -0.0264187 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0262041 |
| CDK13 | cyclin-dependent kinase 13 | -0.0259423 |
| GLG1 | golgi glycoprotein 1 | -0.0258404 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0255092 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0252602 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0251979 |
