| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCDH7 | protocadherin 7 | 0.108099 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0973578 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.096493 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0955296 |
| TENM3 | teneurin transmembrane protein 3 | 0.0724378 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0717301 |
| DST | dystonin | 0.069246 |
| HMGA2 | high mobility group AT-hook 2 | 0.0616551 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0593312 |
| NLGN1 | neuroligin 1 | 0.0591304 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0539142 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0513762 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0512214 |
| LMO7 | LIM domain 7 | 0.0462797 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0460581 |
| ANXA1 | annexin A1 | 0.0436879 |
| MTAP | methylthioadenosine phosphorylase | 0.0424955 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0408871 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0407374 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0396489 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0395846 |
| YAP1 | Yes-associated protein 1 | 0.0394544 |
| GASK1B | golgi associated kinase 1B | 0.0390203 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0383239 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0382538 |
| RPL4 | ribosomal protein L4 | 0.0381135 |
| PDGFC | platelet derived growth factor C | 0.0378213 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0374378 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0354852 |
| NEBL | nebulette | 0.0351888 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341013 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G | 0.0339163 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0331931 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0326072 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0324274 |
| TPM3 | tropomyosin 3 | 0.032084 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309935 |
| EXOC6B | exocyst complex component 6B | 0.0302899 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0291227 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0291158 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0290379 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.0288284 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0277387 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0270896 |
| AHNAK | AHNAK nucleoprotein | 0.0264182 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0263604 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0259135 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0253177 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0250027 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0249138 |
| PAPOLA | poly(A) polymerase alpha | 0.0248679 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0246273 |
| RASAL2 | RAS protein activator like 2 | 0.0238145 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0237916 |
| EPHA6 | EPH receptor A6 | 0.0236497 |
| TXNRD1 | thioredoxin reductase 1 | 0.0234035 |
| ZNF804A | zinc finger protein 804A | 0.0233626 |
| PHF3 | PHD finger protein 3 | 0.0229553 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226349 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0225672 |
| MMP12 | matrix metallopeptidase 12 | 0.0224955 |
| NEK7 | NIMA-related kinase 7 | 0.0222922 |
| EGFR | epidermal growth factor receptor | 0.0222624 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0222201 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0220979 |
| AXIN2 | axin 2 | 0.0219639 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0215926 |
| CANX | calnexin | 0.0214714 |
| OXR1 | oxidation resistance 1 | 0.0212118 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0211193 |
| TMEM123 | transmembrane protein 123 | 0.0210212 |
| BCHE | butyrylcholinesterase | 0.0209895 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0205027 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0197766 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0197748 |
| SUMF1 | sulfatase modifying factor 1 | 0.0196397 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | 0.0195423 |
| MGAT4C | MGAT4 family, member C | 0.0194729 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0194366 |
| NBEA | neurobeachin | 0.0193312 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0192098 |
| ATP11A | ATPase, class VI, type 11A | 0.0191857 |
| ZNF146 | zinc finger protein 146 | 0.0189864 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0189012 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0185137 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0184591 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0183356 |
| SERINC1 | serine incorporator 1 | 0.0182907 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.018164 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.01809 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0178768 |
| AATF | apoptosis antagonizing transcription factor | 0.0176216 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0176098 |
| APP | amyloid beta (A4) precursor protein | 0.0175095 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0174722 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0173584 |
| MPG | N-methylpurine-DNA glycosylase | 0.0172996 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0170755 |
| SET | SET nuclear proto-oncogene | 0.0169933 |
| RUBCN | rubicon autophagy regulator | 0.016921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146465 |
| VIM | vimentin | -0.137411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.105245 |
| FTL | ferritin, light polypeptide | -0.0942073 |
| TMSB10 | thymosin beta 10 | -0.0656379 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0587292 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0534958 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0508947 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0504222 |
| RPL35A | ribosomal protein L35a | -0.0480369 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0454906 |
| KPNB1 | karyopherin (importin) beta 1 | -0.045052 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0445311 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0443202 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0433588 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0430219 |
| USP34 | ubiquitin specific peptidase 34 | -0.042504 |
| PFN1 | profilin 1 | -0.0419155 |
| EGR1 | early growth response 1 | -0.041314 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0409973 |
| NF1 | neurofibromin 1 | -0.0406018 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0402196 |
| JMJD1C | jumonji domain containing 1C | -0.0394996 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0378286 |
| PCBP2 | poly(rC) binding protein 2 | -0.0366935 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.035751 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0353087 |
| TMEM41B | transmembrane protein 41B | -0.0351543 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0349809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.034532 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0345096 |
| ZNF638 | zinc finger protein 638 | -0.0339134 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0325237 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0324632 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.031874 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.031793 |
| AREG | amphiregulin | -0.0314572 |
| ATXN2 | ataxin 2 | -0.0309649 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.030515 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0301149 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0298981 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0296249 |
| RPS6 | ribosomal protein S6 | -0.0295663 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293523 |
| S100A6 | S100 calcium binding protein A6 | -0.0293211 |
| ACTG1 | actin gamma 1 | -0.0288919 |
| ZNF207 | zinc finger protein 207 | -0.0287925 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.028555 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0282849 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0278736 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0278521 |
| TUBA1B | tubulin, alpha 1b | -0.0278378 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0277612 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277463 |
| RSF1 | remodeling and spacing factor 1 | -0.0275212 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.027428 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0265195 |
| ARF4 | ADP-ribosylation factor 4 | -0.0264788 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264531 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0263045 |
| VMP1 | vacuole membrane protein 1 | -0.0259735 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0258794 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0258012 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0257793 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0255533 |
| GCG | glucagon | -0.0253409 |
| PTMA | prothymosin, alpha | -0.0252954 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0247867 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.024531 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0242068 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241852 |
| MAP1B | microtubule-associated protein 1B | -0.0241363 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0241157 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.024097 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0239232 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0237061 |
| CDK19 | cyclin-dependent kinase 19 | -0.0233702 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0231745 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0230048 |
| FBXO11 | F-box protein 11 | -0.0228201 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0226209 |
| GNAS | GNAS complex locus | -0.0225684 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0224501 |
| CDC27 | cell division cycle 27 | -0.022426 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0222776 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0220959 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.022067 |
| RBM39 | RNA binding motif protein 39 | -0.022044 |
| R3HDM1 | R3H domain containing 1 | -0.022042 |
| SYT1 | synaptotagmin I | -0.022004 |
| ENO1 | enolase 1, (alpha) | -0.021762 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0216995 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0214196 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0213795 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0213417 |
| HMGA1 | high mobility group AT-hook 1 | -0.0211441 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0211099 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.020937 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.02092 |
| SEPTIN7 | septin 7 | -0.0207284 |
