| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGB1 | golgin B1 | 0.0702506 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0675291 |
| VEGFA | vascular endothelial growth factor A | 0.0626747 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.052709 |
| CCNL1 | cyclin L1 | 0.0519802 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0502934 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0466766 |
| INTS6 | integrator complex subunit 6 | 0.0431002 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.041761 |
| DSPP | dentin sialophosphoprotein | 0.0412177 |
| UBN2 | ubinuclein 2 | 0.0409425 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0405003 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0390457 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0386779 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.038221 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.037872 |
| TMF1 | TATA element modulatory factor 1 | 0.0374988 |
| SQSTM1 | sequestosome 1 | 0.0360934 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.035923 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0344326 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0341904 |
| B2M | beta-2-microglobulin | 0.03362 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0334542 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0330622 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0329131 |
| CDHR2 | cadherin-related family member 2 | 0.0320891 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0320155 |
| DST | dystonin | 0.0317401 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0312724 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0306532 |
| ZNF609 | zinc finger protein 609 | 0.0301722 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.030062 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0299774 |
| SPAG9 | sperm associated antigen 9 | 0.0289145 |
| OGA | O-GlcNAcase | 0.0285862 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0285497 |
| BRD2 | bromodomain containing 2 | 0.0283594 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0282182 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0279335 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0276364 |
| TMC5 | transmembrane channel-like 5 | 0.0274747 |
| RPL21 | ribosomal protein L21 | 0.0268279 |
| MCL1 | myeloid cell leukemia 1 | 0.0266261 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0263391 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0261955 |
| CPNE4 | copine IV | 0.0260709 |
| TPM3 | tropomyosin 3 | 0.0259237 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0258795 |
| BSDC1 | BSD domain containing 1 | 0.0258641 |
| RPL7 | ribosomal protein L7 | 0.0256857 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0242174 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0242049 |
| TAOK3 | TAO kinase 3 | 0.0240225 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0236305 |
| ZNF148 | zinc finger protein 148 | 0.0235437 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0234976 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0234779 |
| XDH | xanthine dehydrogenase | 0.023319 |
| SFTPA2 | surfactant protein A2 | 0.0227719 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0227155 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0225875 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0223564 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0222972 |
| ZNF841 | zinc finger protein 841 | 0.0220757 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0218272 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0217815 |
| HYOU1 | hypoxia up-regulated 1 | 0.0216141 |
| PMM2 | phosphomannomutase 2 | 0.0214602 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0213295 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0212769 |
| PCBP2 | poly(rC) binding protein 2 | 0.0208987 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.020815 |
| PGM3 | phosphoglucomutase 3 | 0.0208023 |
| HDLBP | high density lipoprotein binding protein | 0.0204502 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0203404 |
| IRS2 | insulin receptor substrate 2 | 0.0202603 |
| FOSL2 | FOS-like antigen 2 | 0.0202549 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0201627 |
| SLK | STE20-like kinase | 0.0201398 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0201117 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0199943 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0199059 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0199044 |
| ALPK1 | alpha-kinase 1 | 0.0198673 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0198113 |
| ITGA6 | integrin, alpha 6 | 0.0196512 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0195794 |
| LIMA1 | LIM domain and actin binding 1 | 0.0195631 |
| SAA2-SAA4 | SAA2-SAA4 readthrough | 0.0195293 |
| RPS17 | ribosomal protein S17 | 0.0195134 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0194547 |
| MBTD1 | mbt domain containing 1 | 0.0193814 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0192383 |
| HUNK | hormonally up-regulated Neu-associated kinase | 0.0191589 |
| HELZ | helicase with zinc finger | 0.0190501 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0189574 |
| KIF16B | kinesin family member 16B | 0.0189132 |
| FAM13A | family with sequence similarity 13, member A | 0.0188761 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0188479 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.018724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.116453 |
| RUNX1 | runt-related transcription factor 1 | -0.115284 |
| NDRG1 | N-myc downstream regulated 1 | -0.098734 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0948852 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0932141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0882588 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0863283 |
| ANXA2 | annexin A2 | -0.0819836 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0768909 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0711971 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0688163 |
| RNF43 | ring finger protein 43 | -0.0682886 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.067608 |
| VCL | vinculin | -0.0674895 |
| PERP | PERP, TP53 apoptosis effector | -0.0673779 |
| H1-0 | H1.0 linker histone | -0.0668416 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0663189 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0630428 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0618827 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0618768 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0597159 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0578047 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0575599 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0558937 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0550557 |
| NF1 | neurofibromin 1 | -0.0549808 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0521861 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0513992 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0510974 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0502479 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0501143 |
| XAF1 | XIAP associated factor 1 | -0.0496029 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0480458 |
| STK24 | serine/threonine kinase 24 | -0.0467062 |
| ATP11A | ATPase, class VI, type 11A | -0.0464299 |
| DENND4C | DENN/MADD domain containing 4C | -0.0462903 |
| TXNRD1 | thioredoxin reductase 1 | -0.0456885 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0447967 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0445428 |
| PGK1 | phosphoglycerate kinase 1 | -0.0441279 |
| EPCAM | epithelial cell adhesion molecule | -0.0438491 |
| MX2 | MX dynamin-like GTPase 2 | -0.0409789 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0395495 |
| ANXA4 | annexin A4 | -0.0395332 |
| SERINC5 | serine incorporator 5 | -0.0394158 |
| FOXP1 | forkhead box P1 | -0.0386547 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0379122 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0378806 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0374702 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0373291 |
| ACTN4 | actinin, alpha 4 | -0.0372789 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0363125 |
| CLYBL | citrate lyase beta like | -0.0361625 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.035902 |
| TXNIP | thioredoxin interacting protein | -0.0349738 |
| EPHB2 | EPH receptor B2 | -0.0345338 |
| RPS24 | ribosomal protein S24 | -0.0342501 |
| UBL3 | ubiquitin-like 3 | -0.034173 |
| PLSCR1 | phospholipid scramblase 1 | -0.0341293 |
| RRBP1 | ribosome binding protein 1 | -0.0339154 |
| TJP1 | tight junction protein 1 | -0.0337213 |
| ERBIN | erbb2 interacting protein | -0.0336886 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0335694 |
| SPATA13 | spermatogenesis associated 13 | -0.0335636 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0335329 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0333425 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0333327 |
| EHF | ets homologous factor | -0.0330204 |
| APP | amyloid beta (A4) precursor protein | -0.0326313 |
| FHL2 | four and a half LIM domains 2 | -0.03236 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0323568 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0321835 |
| LNX2 | ligand of numb-protein X 2 | -0.0321808 |
| TMEM62 | transmembrane protein 62 | -0.0319511 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0312972 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0311651 |
| KLF6 | Kruppel-like factor 6 | -0.0311558 |
| HMGB1 | high mobility group box 1 | -0.0311436 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0311325 |
| PTMA | prothymosin, alpha | -0.0309888 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0307557 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0306294 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.030618 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0304808 |
| ITM2B | integral membrane protein 2B | -0.0300702 |
| NUP214 | nucleoporin 214kDa | -0.0300181 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0299436 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.02984 |
| MUC13 | mucin 13, cell surface associated | -0.0297434 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0296075 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0293714 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0293626 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0293214 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0292529 |
| HLA-B | major histocompatibility complex, class I, B | -0.0291259 |
| GSE1 | Gse1 coiled-coil protein | -0.0290699 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0287656 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0284981 |
| AOPEP | aminopeptidase O (putative) | -0.0284629 |
| ATP9A | ATPase, class II, type 9A | -0.0283257 |
