| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.216993 |
| COL6A3 | collagen, type VI, alpha 3 | 0.169853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.134402 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0716929 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0707596 |
| VCAN | versican | 0.0693776 |
| TMSB4X | thymosin beta 4, X-linked | 0.0599222 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0598395 |
| PLEC | plectin | 0.0585177 |
| ATP13A3 | ATPase type 13A3 | 0.0526753 |
| CCNL1 | cyclin L1 | 0.050144 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0496042 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0491347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0473808 |
| DST | dystonin | 0.0466269 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0462358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.044662 |
| CADM1 | cell adhesion molecule 1 | 0.0443037 |
| POTEF | POTE ankyrin domain family, member F | 0.0437189 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0432022 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0429605 |
| PTK2 | protein tyrosine kinase 2 | 0.0385111 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0380721 |
| B2M | beta-2-microglobulin | 0.0367355 |
| NAV2 | neuron navigator 2 | 0.0359845 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0357009 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0355461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0342615 |
| CALD1 | caldesmon 1 | 0.0334318 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0329927 |
| MSN | moesin | 0.0326951 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.031629 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314413 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0307226 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0299911 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0295391 |
| RPL3 | ribosomal protein L3 | 0.0288263 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.028453 |
| TPM3 | tropomyosin 3 | 0.028328 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.028122 |
| AXL | AXL receptor tyrosine kinase | 0.0280085 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278413 |
| TNS1 | tensin 1 | 0.0277309 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0275313 |
| GOLGA4 | golgin A4 | 0.0274484 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0274001 |
| NAV1 | neuron navigator 1 | 0.0271399 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0265606 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0262697 |
| BRD2 | bromodomain containing 2 | 0.0258603 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0257823 |
| SMAD3 | SMAD family member 3 | 0.0256321 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0255413 |
| MATR3 | matrin 3 | 0.025217 |
| ANO6 | anoctamin 6 | 0.0246193 |
| SETD5 | SET domain containing 5 | 0.0245426 |
| MYO10 | myosin X | 0.0242029 |
| MTSS1 | metastasis suppressor 1 | 0.0240632 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0238472 |
| ITGAV | integrin, alpha V | 0.0237742 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0236055 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235701 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0233627 |
| TPM2 | tropomyosin 2 (beta) | 0.0230445 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.022742 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0223795 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0222212 |
| DSTN | destrin (actin depolymerizing factor) | 0.0221823 |
| PNN | pinin, desmosome associated protein | 0.0220712 |
| RPL4 | ribosomal protein L4 | 0.0219335 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0217899 |
| TMF1 | TATA element modulatory factor 1 | 0.0217828 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0217195 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0215782 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0212726 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0212596 |
| PGM3 | phosphoglucomutase 3 | 0.021174 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0209604 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0209587 |
| EHBP1 | EH domain binding protein 1 | 0.0208875 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0208839 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0207837 |
| FLNA | filamin A, alpha | 0.020743 |
| TPR | translocated promoter region, nuclear basket protein | 0.0207106 |
| CENPF | centromere protein F, 350/400kDa | 0.0206864 |
| SDC4 | syndecan 4 | 0.0206271 |
| RNF145 | ring finger protein 145 | 0.0205474 |
| COPA | coatomer protein complex, subunit alpha | 0.0205312 |
| OPTN | optineurin | 0.0205026 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0204928 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0203696 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0203422 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0203069 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0200739 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0199065 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0198747 |
| DENND1A | DENN/MADD domain containing 1A | 0.0196715 |
| CCDC80 | coiled-coil domain containing 80 | 0.0196463 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0195604 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0193708 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.3809 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.286763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.242569 |
| NDRG1 | N-myc downstream regulated 1 | -0.200427 |
| CD44 | CD44 molecule (Indian blood group) | -0.101163 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0608575 |
| IER3 | immediate early response 3 | -0.0541352 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0507273 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0455251 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0426492 |
| CANX | calnexin | -0.0419059 |
| FTL | ferritin, light polypeptide | -0.0412174 |
| VIM | vimentin | -0.038601 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0381666 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0354543 |
| LOX | lysyl oxidase | -0.0354363 |
| GNAS | GNAS complex locus | -0.0352302 |
| ANXA2 | annexin A2 | -0.0335141 |
| UBC | ubiquitin C | -0.0330859 |
| RPL35A | ribosomal protein L35a | -0.0325986 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0324826 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0303786 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0280753 |
| MT2A | metallothionein 2A | -0.0279586 |
| TAPBP | TAP binding protein (tapasin) | -0.0278355 |
| IL6ST | interleukin 6 signal transducer | -0.0269407 |
| COL1A1 | collagen, type I, alpha 1 | -0.0267969 |
| ACTG1 | actin gamma 1 | -0.0263189 |
| RRBP1 | ribosome binding protein 1 | -0.0261764 |
| MT1X | metallothionein 1X | -0.025979 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.02566 |
| TUBB | tubulin, beta class I | -0.0256173 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0249835 |
| OSMR | oncostatin M receptor | -0.0249475 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0248614 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0248094 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0245636 |
| TRAM2 | translocation associated membrane protein 2 | -0.024386 |
| RIGI | RNA sensor RIG-I | -0.0242217 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.023696 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0228946 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0223352 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0223052 |
| JMJD1C | jumonji domain containing 1C | -0.0221468 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0216886 |
| POSTN | periostin, osteoblast specific factor | -0.0215542 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0215525 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0212029 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0209825 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0207915 |
| EHD2 | EH-domain containing 2 | -0.0207129 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.020661 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0205215 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0204379 |
| CLTC | clathrin, heavy chain (Hc) | -0.0202967 |
| OGA | O-GlcNAcase | -0.0201094 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0200351 |
| KLF6 | Kruppel-like factor 6 | -0.0199088 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.019889 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0198516 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0198311 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0196591 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0194734 |
| BSG | basigin (Ok blood group) | -0.0192417 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0192235 |
| RPS24 | ribosomal protein S24 | -0.0191434 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.019084 |
| PALLD | palladin, cytoskeletal associated protein | -0.0190771 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0188247 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0187261 |
| PXDN | peroxidasin | -0.0187109 |
| LDHA | lactate dehydrogenase A | -0.0186304 |
| BBX | bobby sox homolog (Drosophila) | -0.0183856 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0181102 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.018027 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0180005 |
| MORF4L2 | mortality factor 4 like 2 | -0.017991 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0178256 |
| MX2 | MX dynamin-like GTPase 2 | -0.0177719 |
| TMSB10 | thymosin beta 10 | -0.0175249 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0174431 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0173634 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0170176 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0169983 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0167588 |
| EGR1 | early growth response 1 | -0.0166228 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0165823 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0165696 |
| RPLP0 | ribosomal protein, large, P0 | -0.0165513 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0164791 |
| SELENOF | selenoprotein F | -0.016431 |
| ZFR | zinc finger RNA binding protein | -0.0162992 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0162222 |
| ARF1 | ADP-ribosylation factor 1 | -0.0161822 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0161751 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0161654 |
| FOXJ3 | forkhead box J3 | -0.0161445 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0161044 |
| CAVIN1 | caveolae associated protein 1 | -0.0159668 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0159243 |
