| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.0859337 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0811767 |
| MSN | moesin | 0.078449 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0724463 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0723998 |
| PLEC | plectin | 0.0694754 |
| TPM3 | tropomyosin 3 | 0.0541822 |
| TMSB4X | thymosin beta 4, X-linked | 0.0540085 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0509409 |
| POTEF | POTE ankyrin domain family, member F | 0.047866 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0442729 |
| B2M | beta-2-microglobulin | 0.0437195 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0407379 |
| SLK | STE20-like kinase | 0.0368611 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0366306 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0359545 |
| RBM39 | RNA binding motif protein 39 | 0.0356264 |
| RPL21 | ribosomal protein L21 | 0.035539 |
| CCNL1 | cyclin L1 | 0.0350545 |
| VEGFA | vascular endothelial growth factor A | 0.034765 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0335762 |
| DIAPH1 | diaphanous-related formin 1 | 0.0315163 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0303593 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0303387 |
| GOLGA4 | golgin A4 | 0.02988 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0294212 |
| SEPTIN9 | septin 9 | 0.0292515 |
| RPL3 | ribosomal protein L3 | 0.0291911 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0290842 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0290056 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0288125 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0286766 |
| SIK3 | SIK family kinase 3 | 0.0285003 |
| CRY1 | cryptochrome circadian clock 1 | 0.0281557 |
| SFPQ | splicing factor proline/glutamine-rich | 0.027987 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.027541 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.027536 |
| PTK2 | protein tyrosine kinase 2 | 0.0274029 |
| BLCAP | bladder cancer associated protein | 0.0272473 |
| HDGF | hepatoma-derived growth factor | 0.027057 |
| ATP13A3 | ATPase type 13A3 | 0.0270463 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0270346 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0268786 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0267852 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0267123 |
| RNF145 | ring finger protein 145 | 0.026348 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0260032 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0258013 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0256876 |
| RPL4 | ribosomal protein L4 | 0.0255273 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0253962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0251911 |
| PLS3 | plastin 3 | 0.0251791 |
| FOSL1 | FOS-like antigen 1 | 0.0246814 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0241553 |
| NEK7 | NIMA-related kinase 7 | 0.0239878 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0239378 |
| LUZP1 | leucine zipper protein 1 | 0.0239141 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0239011 |
| DSTN | destrin (actin depolymerizing factor) | 0.0238419 |
| RNF19B | ring finger protein 19B | 0.0237765 |
| AMOTL1 | angiomotin like 1 | 0.0236256 |
| KRT14 | keratin 14, type I | 0.0234408 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0234023 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0233365 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.023293 |
| RUNX1 | runt-related transcription factor 1 | 0.0232916 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0232601 |
| FMNL2 | formin-like 2 | 0.0229449 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0224615 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0223878 |
| MCL1 | myeloid cell leukemia 1 | 0.0221396 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219859 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0219489 |
| HMGA1 | high mobility group AT-hook 1 | 0.021878 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0216463 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0213975 |
| ANXA11 | annexin A11 | 0.0210074 |
| FOXJ3 | forkhead box J3 | 0.02087 |
| DIDO1 | death inducer-obliterator 1 | 0.0207073 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0205303 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0204704 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0202698 |
| RBM26 | RNA binding motif protein 26 | 0.0202327 |
| SET | SET nuclear proto-oncogene | 0.0201112 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0200836 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0200128 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0200125 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0200036 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0198707 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0198532 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0198039 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0197669 |
| TXNRD1 | thioredoxin reductase 1 | 0.019761 |
| NONO | non-POU domain containing, octamer-binding | 0.0196272 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.0196162 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0195364 |
| IFI44L | interferon-induced protein 44-like | 0.0195178 |
| CD47 | CD47 molecule | 0.0195118 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.299002 |
| NDRG1 | N-myc downstream regulated 1 | -0.230705 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141226 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0982467 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0977652 |
| ENO1 | enolase 1, (alpha) | -0.0923334 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0920723 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0825966 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0722138 |
| EMP1 | epithelial membrane protein 1 | -0.0713337 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0707799 |
| H1-0 | H1.0 linker histone | -0.0701071 |
| GNAS | GNAS complex locus | -0.0682953 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0662332 |
| FLNB | filamin B, beta | -0.0629607 |
| SULF1 | sulfatase 1 | -0.0576487 |
| RAI14 | retinoic acid induced 14 | -0.0565605 |
| PGK1 | phosphoglycerate kinase 1 | -0.056418 |
| PRELID2 | PRELI domain containing 2 | -0.0545414 |
| CUL4B | cullin 4B | -0.054145 |
| RIGI | RNA sensor RIG-I | -0.0525539 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0517813 |
| AHNAK | AHNAK nucleoprotein | -0.0513046 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0498011 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0497472 |
| ANXA1 | annexin A1 | -0.0492388 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0490168 |
| CANX | calnexin | -0.0485666 |
| ANLN | anillin, actin binding protein | -0.0482016 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0456923 |
| CAVIN1 | caveolae associated protein 1 | -0.0443544 |
| MYOF | myoferlin | -0.0438497 |
| ANXA2 | annexin A2 | -0.0437188 |
| MORF4L2 | mortality factor 4 like 2 | -0.0436459 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0430415 |
| FN1 | fibronectin 1 | -0.0418577 |
| MTSS1 | metastasis suppressor 1 | -0.0416956 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0414823 |
| S100A10 | S100 calcium binding protein A10 | -0.0411805 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0407484 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0405676 |
| ASPH | aspartate beta-hydroxylase | -0.0405254 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0404079 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0401753 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0397919 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0393748 |
| CALU | calumenin | -0.0391546 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0386818 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0383686 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0375769 |
| PALLD | palladin, cytoskeletal associated protein | -0.0372089 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0370268 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0368719 |
| TMSB10 | thymosin beta 10 | -0.036864 |
| ZNF217 | zinc finger protein 217 | -0.0360614 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0357759 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0354908 |
| ARF1 | ADP-ribosylation factor 1 | -0.0347511 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0346819 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0342696 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0341197 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0332314 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0329747 |
| LMNA | lamin A/C | -0.0329629 |
| MECOM | MDS1 and EVI1 complex locus | -0.0328329 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0325902 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0322543 |
| OSMR | oncostatin M receptor | -0.0316993 |
| INTS6 | integrator complex subunit 6 | -0.0308146 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0301263 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0298059 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0297313 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0297018 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0296739 |
| THBD | thrombomodulin | -0.0296076 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0289574 |
| ITGB4 | integrin, beta 4 | -0.0289084 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0288912 |
| KRT6A | keratin 6A, type II | -0.0286129 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0285973 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0283159 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.027975 |
| RPS24 | ribosomal protein S24 | -0.0278587 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276271 |
| LOXL2 | lysyl oxidase-like 2 | -0.0272241 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270619 |
| PYGL | phosphorylase, glycogen, liver | -0.0269089 |
| RSRP1 | arginine/serine-rich protein 1 | -0.026323 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0262183 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0259498 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0258969 |
| ANGPTL4 | angiopoietin-like 4 | -0.0257205 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.025711 |
| RIN2 | Ras and Rab interactor 2 | -0.0256325 |
| S100A4 | S100 calcium binding protein A4 | -0.0256177 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.025385 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0253717 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0252927 |
| CRACDL | CRACD like | -0.0251425 |
| CD99 | CD99 molecule | -0.025119 |
