| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0676383 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0590499 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0461866 |
| ATP13A3 | ATPase type 13A3 | 0.0428962 |
| EFNA5 | ephrin-A5 | 0.034664 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0331804 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0310154 |
| SMAD3 | SMAD family member 3 | 0.0306692 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267961 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0267258 |
| RBM39 | RNA binding motif protein 39 | 0.0267182 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0262811 |
| FAM20C | family with sequence similarity 20, member C | 0.0261929 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0259449 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.024952 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0242999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0236311 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0231471 |
| PRELID2 | PRELI domain containing 2 | 0.022174 |
| CAB39 | calcium binding protein 39 | 0.0217833 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0216943 |
| VEGFA | vascular endothelial growth factor A | 0.0215402 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0214595 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0213709 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0212976 |
| CCNL1 | cyclin L1 | 0.0204943 |
| MSN | moesin | 0.0202163 |
| STK38L | serine/threonine kinase 38 like | 0.0200078 |
| ADD3 | adducin 3 (gamma) | 0.0196329 |
| NPC1 | Niemann-Pick disease, type C1 | 0.01886 |
| RPL4 | ribosomal protein L4 | 0.0188343 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0187151 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0183184 |
| KYNU | kynureninase | 0.0175406 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.017294 |
| CEP250 | centrosomal protein 250kDa | 0.0172774 |
| RUNX2 | runt-related transcription factor 2 | 0.0171173 |
| FAM107B | family with sequence similarity 107, member B | 0.0166361 |
| AHR | aryl hydrocarbon receptor | 0.0163506 |
| HELZ | helicase with zinc finger | 0.0160649 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.016057 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0160466 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0160254 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0158592 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158401 |
| CYTH1 | cytohesin 1 | 0.0158348 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0157674 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0156712 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0154877 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0153411 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0153104 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0152926 |
| FRMD4A | FERM domain containing 4A | 0.0152541 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0151515 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0151069 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0151026 |
| EWSR1 | EWS RNA-binding protein 1 | 0.014913 |
| SMYD3 | SET and MYND domain containing 3 | 0.0144193 |
| NAV2 | neuron navigator 2 | 0.0142907 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0142545 |
| ANKRD11 | ankyrin repeat domain 11 | 0.014127 |
| USP24 | ubiquitin specific peptidase 24 | 0.0140391 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0140384 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0140315 |
| TPM3 | tropomyosin 3 | 0.0138376 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0138132 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0136902 |
| MYO6 | myosin VI | 0.0135512 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0134981 |
| TJP1 | tight junction protein 1 | 0.013353 |
| SP3 | Sp3 transcription factor | 0.0133418 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0132447 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0131914 |
| DNMBP | dynamin binding protein | 0.0131783 |
| RNF145 | ring finger protein 145 | 0.0131143 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0130573 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0129044 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0128823 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0127788 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0126598 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0125791 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0124061 |
| IFI44 | interferon-induced protein 44 | 0.0123538 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0122748 |
| SMOX | spermine oxidase | 0.0122395 |
| SIK3 | SIK family kinase 3 | 0.012197 |
| THOC1 | THO complex 1 | 0.0121664 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0121514 |
| CENPF | centromere protein F, 350/400kDa | 0.0121228 |
| SECISBP2L | SECIS binding protein 2-like | 0.0120082 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0119634 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0119611 |
| TXNRD1 | thioredoxin reductase 1 | 0.0119282 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0118936 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0117949 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0116581 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0116244 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0116074 |
| RUNX1 | runt-related transcription factor 1 | 0.0115506 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0114815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.305386 |
| VIM | vimentin | -0.187277 |
| TMSB10 | thymosin beta 10 | -0.135972 |
| FTL | ferritin, light polypeptide | -0.120568 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104213 |
| LOX | lysyl oxidase | -0.0994665 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0817748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0772724 |
| FN1 | fibronectin 1 | -0.0737816 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0715986 |
| PTMA | prothymosin, alpha | -0.0684607 |
| NDRG1 | N-myc downstream regulated 1 | -0.066424 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0662194 |
| RPLP1 | ribosomal protein, large, P1 | -0.0585433 |
| MT2A | metallothionein 2A | -0.0521086 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0518083 |
| IER3 | immediate early response 3 | -0.0507042 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0505463 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0504922 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0501745 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0481986 |
| LMAN1 | lectin, mannose-binding, 1 | -0.048034 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0462016 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0461647 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0451989 |
| STC1 | stanniocalcin 1 | -0.0448435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0436909 |
| ENO1 | enolase 1, (alpha) | -0.0434544 |
| EGR1 | early growth response 1 | -0.0427272 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0426328 |
| CA12 | carbonic anhydrase XII | -0.04254 |
| S100A6 | S100 calcium binding protein A6 | -0.0420082 |
| CANX | calnexin | -0.0418638 |
| RPS19 | ribosomal protein S19 | -0.041818 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0410806 |
| RPS6 | ribosomal protein S6 | -0.0405501 |
| RPL35A | ribosomal protein L35a | -0.0394866 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0394126 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391192 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0386681 |
| S100A10 | S100 calcium binding protein A10 | -0.0384342 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0383976 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0375668 |
| GNAS | GNAS complex locus | -0.0360944 |
| UBC | ubiquitin C | -0.0346055 |
| RPS8 | ribosomal protein S8 | -0.0342746 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.03402 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.03334 |
| TMEM263 | transmembrane protein 263 | -0.0332755 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0332721 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331719 |
| RPS29 | ribosomal protein S29 | -0.0331064 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0329612 |
| RPL32 | ribosomal protein L32 | -0.0328777 |
| USP34 | ubiquitin specific peptidase 34 | -0.0327114 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.032497 |
| HMGA1 | high mobility group AT-hook 1 | -0.0323108 |
| MAP1B | microtubule-associated protein 1B | -0.0320604 |
| GOLGA4 | golgin A4 | -0.0319314 |
| RPL34 | ribosomal protein L34 | -0.0318357 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0318287 |
| RIOK3 | RIO kinase 3 | -0.0317243 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316388 |
| RPS13 | ribosomal protein S13 | -0.0315769 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0314246 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.031164 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0304917 |
| RPL31 | ribosomal protein L31 | -0.0294595 |
| RPL11 | ribosomal protein L11 | -0.0294151 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290868 |
| LDHA | lactate dehydrogenase A | -0.0289949 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.028669 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0283989 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0281265 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0279712 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0278211 |
| RAI14 | retinoic acid induced 14 | -0.0277175 |
| RPL28 | ribosomal protein L28 | -0.0272381 |
| SYT1 | synaptotagmin I | -0.0271957 |
| RPS25 | ribosomal protein S25 | -0.0270936 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0269929 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0268425 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0263178 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0260929 |
| BPTF | bromodomain PHD finger transcription factor | -0.0260687 |
| MEF2A | myocyte enhancer factor 2A | -0.0257835 |
| RPL37 | ribosomal protein L37 | -0.0255995 |
| MYADM | myeloid-associated differentiation marker | -0.0253388 |
| TGFB1 | transforming growth factor, beta 1 | -0.0252781 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0250384 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0249941 |
| GPC6 | glypican 6 | -0.0248627 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0247499 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0247364 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247222 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0247138 |
| RPS5 | ribosomal protein S5 | -0.0246788 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0246709 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0246442 |
| RPS21 | ribosomal protein S21 | -0.0246357 |
