| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.175343 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.102725 |
| GRAMD1B | GRAM domain containing 1B | 0.0791469 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0779003 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.061323 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0546015 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0519604 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0493032 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0431842 |
| CCNL1 | cyclin L1 | 0.0417718 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0386912 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0379326 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0366111 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.036387 |
| SMAD3 | SMAD family member 3 | 0.0356839 |
| SFPQ | splicing factor proline/glutamine-rich | 0.03487 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0346303 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0342933 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0340082 |
| ATP11A | ATPase, class VI, type 11A | 0.033929 |
| EXOC6B | exocyst complex component 6B | 0.0319458 |
| NABP1 | nucleic acid binding protein 1 | 0.0309675 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303762 |
| RTN4 | reticulon 4 | 0.0295145 |
| PLCB4 | phospholipase C, beta 4 | 0.0289862 |
| PLEC | plectin | 0.0289261 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0281519 |
| WDR43 | WD repeat domain 43 | 0.0280193 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0277298 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0276282 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0273654 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0270671 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0258346 |
| RNF145 | ring finger protein 145 | 0.0257611 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0257573 |
| PCBP2 | poly(rC) binding protein 2 | 0.0257382 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0255637 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0255156 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0253679 |
| ANXA5 | annexin A5 | 0.0252882 |
| TPM3 | tropomyosin 3 | 0.0252651 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0245706 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0244466 |
| BRD4 | bromodomain containing 4 | 0.0243811 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0243371 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0243236 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0242266 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0240353 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0240181 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0240063 |
| OGA | O-GlcNAcase | 0.0236677 |
| ACTN1 | actinin, alpha 1 | 0.0235611 |
| RUNX1 | runt-related transcription factor 1 | 0.0231791 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0228329 |
| SIN3A | SIN3 transcription regulator family member A | 0.0225827 |
| TBK1 | TANK-binding kinase 1 | 0.0223724 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0222945 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0217782 |
| DENND1A | DENN/MADD domain containing 1A | 0.0217778 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0217179 |
| MCL1 | myeloid cell leukemia 1 | 0.0214541 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0214105 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0213555 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0213166 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0212794 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0206191 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0204328 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0204065 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0203703 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0202903 |
| DST | dystonin | 0.0200138 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0200039 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0199077 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0198118 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0197717 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0196263 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0196129 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0194751 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0192651 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.019127 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0191099 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0190267 |
| BRD2 | bromodomain containing 2 | 0.0188204 |
| DIDO1 | death inducer-obliterator 1 | 0.0186723 |
| RLIM | ring finger protein, LIM domain interacting | 0.0184471 |
| SMYD3 | SET and MYND domain containing 3 | 0.0182762 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0182182 |
| ZNF644 | zinc finger protein 644 | 0.0181323 |
| NCKAP1 | NCK-associated protein 1 | 0.0181004 |
| USP24 | ubiquitin specific peptidase 24 | 0.0180691 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0178678 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.017846 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0178245 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0177994 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0177657 |
| TSPAN9 | tetraspanin 9 | 0.0176081 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0175409 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0173817 |
| MYPN | myopalladin | 0.0172577 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.0171781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.358138 |
| PTMA | prothymosin, alpha | -0.109941 |
| VIM | vimentin | -0.0897415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0781053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0709922 |
| TMSB10 | thymosin beta 10 | -0.0681704 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0670721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0623551 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0620623 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0511961 |
| TPI1 | triosephosphate isomerase 1 | -0.0506672 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0503788 |
| ACTG1 | actin gamma 1 | -0.0500509 |
| YBX3 | Y box binding protein 3 | -0.0491263 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0462968 |
| GNAS | GNAS complex locus | -0.0453455 |
| RAD51B | RAD51 paralog B | -0.0438727 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.041707 |
| HMGA2 | high mobility group AT-hook 2 | -0.0382491 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0381949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0366641 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0344959 |
| RPS8 | ribosomal protein S8 | -0.033777 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0329048 |
| MT2A | metallothionein 2A | -0.0325478 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324233 |
| TUBA1B | tubulin, alpha 1b | -0.0324033 |
| STC1 | stanniocalcin 1 | -0.0318581 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0313672 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0312892 |
| DEK | DEK proto-oncogene | -0.0309292 |
| TPM4 | tropomyosin 4 | -0.0301324 |
| S100A10 | S100 calcium binding protein A10 | -0.0300822 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292492 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0283331 |
| RACK1 | receptor for activated C kinase 1 | -0.0282575 |
| RPL37 | ribosomal protein L37 | -0.0270875 |
| RPS3 | ribosomal protein S3 | -0.0267196 |
| RPL12 | ribosomal protein L12 | -0.0262621 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.025669 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0255568 |
| TPM2 | tropomyosin 2 (beta) | -0.0248528 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0246958 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0242149 |
| LMAN1 | lectin, mannose-binding, 1 | -0.024027 |
| FTL | ferritin, light polypeptide | -0.0239878 |
| RPS25 | ribosomal protein S25 | -0.02394 |
| RPL34 | ribosomal protein L34 | -0.0236091 |
| CANX | calnexin | -0.0229971 |
| UBB | ubiquitin B | -0.0226357 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0219594 |
| RPLP0 | ribosomal protein, large, P0 | -0.021528 |
| RPS21 | ribosomal protein S21 | -0.021406 |
| RPLP1 | ribosomal protein, large, P1 | -0.0213757 |
| DTNB | dystrobrevin, beta | -0.021215 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0211949 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0208156 |
| RPL37A | ribosomal protein L37a | -0.0207792 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0207558 |
| RPL8 | ribosomal protein L8 | -0.0207543 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0207427 |
| MT1X | metallothionein 1X | -0.0206686 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0206068 |
| SRP72 | signal recognition particle 72kDa | -0.0204269 |
| MORF4L2 | mortality factor 4 like 2 | -0.0201989 |
| ENOSF1 | enolase superfamily member 1 | -0.0200691 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.020043 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0199702 |
| RPS29 | ribosomal protein S29 | -0.0198336 |
| PYGL | phosphorylase, glycogen, liver | -0.0195777 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0193861 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0192519 |
| PFN1 | profilin 1 | -0.0190404 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0188105 |
| ENO1 | enolase 1, (alpha) | -0.0187407 |
| CCND2 | cyclin D2 | -0.0185701 |
| MRPS5 | mitochondrial ribosomal protein S5 | -0.0184425 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0180477 |
| EGR1 | early growth response 1 | -0.0178802 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0178129 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0177267 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.017702 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0175436 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0175305 |
| TUBB | tubulin, beta class I | -0.0174262 |
| RPL9 | ribosomal protein L9 | -0.0173649 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0172721 |
| UBC | ubiquitin C | -0.01718 |
| RPL31 | ribosomal protein L31 | -0.017173 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0169968 |
| RPS19 | ribosomal protein S19 | -0.0168859 |
| RPS15 | ribosomal protein S15 | -0.0168644 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0168183 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0168104 |
| FSCN1 | fascin actin-bundling protein 1 | -0.016561 |
| CALR | calreticulin | -0.0163863 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.0162687 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0160437 |
| RPL38 | ribosomal protein L38 | -0.0160293 |
| HLA-B | major histocompatibility complex, class I, B | -0.0160064 |
