| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.0686409 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.051044 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0479363 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0457609 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0452843 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0449105 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0441793 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0420849 |
| NEK7 | NIMA-related kinase 7 | 0.0363082 |
| WDR43 | WD repeat domain 43 | 0.0309767 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0288058 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.028758 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0283315 |
| RTN4 | reticulon 4 | 0.0269267 |
| ATP13A3 | ATPase type 13A3 | 0.0265024 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0257277 |
| CD109 | CD109 molecule | 0.0251927 |
| TXNRD1 | thioredoxin reductase 1 | 0.0244568 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0243059 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0239412 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0236102 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0221661 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0221624 |
| EFNA5 | ephrin-A5 | 0.0217457 |
| RLIM | ring finger protein, LIM domain interacting | 0.0214854 |
| NCKAP1 | NCK-associated protein 1 | 0.0214329 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0210212 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0208472 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0205352 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0203279 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0201535 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0198643 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0198361 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0194053 |
| RBM39 | RNA binding motif protein 39 | 0.0189993 |
| NBAS | neuroblastoma amplified sequence | 0.0189206 |
| PTEN | phosphatase and tensin homolog | 0.0186466 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0183923 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0181991 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0168967 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0167873 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0165792 |
| CCNL1 | cyclin L1 | 0.0165739 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0165635 |
| OGA | O-GlcNAcase | 0.0165333 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0164967 |
| DST | dystonin | 0.0159415 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.015681 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0156323 |
| GPRIN3 | GPRIN family member 3 | 0.0154373 |
| TPM3 | tropomyosin 3 | 0.0153696 |
| ENAH | enabled homolog (Drosophila) | 0.0152181 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0150388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0149089 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0145516 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0144834 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0140656 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0139754 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0139746 |
| MSN | moesin | 0.013866 |
| YTHDC1 | YTH domain containing 1 | 0.0137597 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0137197 |
| CUL3 | cullin 3 | 0.0135044 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0133503 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0133412 |
| FAT1 | FAT atypical cadherin 1 | 0.0133078 |
| SP3 | Sp3 transcription factor | 0.0131031 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0128299 |
| USP3 | ubiquitin specific peptidase 3 | 0.0127962 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0127622 |
| RPL4 | ribosomal protein L4 | 0.0127053 |
| COPA | coatomer protein complex, subunit alpha | 0.0127022 |
| CTSC | cathepsin C | 0.0126082 |
| PTK2 | protein tyrosine kinase 2 | 0.0124502 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0124144 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0122661 |
| USP15 | ubiquitin specific peptidase 15 | 0.0122395 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0120768 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0120653 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0119335 |
| SPAG9 | sperm associated antigen 9 | 0.0118144 |
| NRG1 | neuregulin 1 | 0.0117702 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0117098 |
| ASPH | aspartate beta-hydroxylase | 0.0116865 |
| RPL3 | ribosomal protein L3 | 0.0116635 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0116052 |
| ANKRD28 | ankyrin repeat domain 28 | 0.011542 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0113143 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0112857 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.011231 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0112034 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0111976 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0111947 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0111742 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0111314 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0110993 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0110906 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0110596 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0110378 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0110317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.38169 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.184673 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.179164 |
| VIM | vimentin | -0.135411 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121268 |
| TMSB10 | thymosin beta 10 | -0.121042 |
| FTL | ferritin, light polypeptide | -0.117378 |
| RPS6 | ribosomal protein S6 | -0.0990729 |
| RPLP1 | ribosomal protein, large, P1 | -0.0950556 |
| PTMA | prothymosin, alpha | -0.0915026 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0806133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0663519 |
| MT2A | metallothionein 2A | -0.0654444 |
| RPL12 | ribosomal protein L12 | -0.0637999 |
| RPS8 | ribosomal protein S8 | -0.0634142 |
| RPL31 | ribosomal protein L31 | -0.061241 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0595862 |
| GNAS | GNAS complex locus | -0.0588899 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0586353 |
| RPL35A | ribosomal protein L35a | -0.0572148 |
| RPS24 | ribosomal protein S24 | -0.0567467 |
| RPL19 | ribosomal protein L19 | -0.056524 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0548423 |
| RPS19 | ribosomal protein S19 | -0.0541972 |
| ACTG1 | actin gamma 1 | -0.0537244 |
| RPL37A | ribosomal protein L37a | -0.0534968 |
| RPLP0 | ribosomal protein, large, P0 | -0.0531735 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0530322 |
| PDE10A | phosphodiesterase 10A | -0.0523648 |
| FN1 | fibronectin 1 | -0.051782 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0508493 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0492232 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0485924 |
| RPL26 | ribosomal protein L26 | -0.0480312 |
| RPS12 | ribosomal protein S12 | -0.047446 |
| RPS23 | ribosomal protein S23 | -0.047387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0457942 |
| ENO1 | enolase 1, (alpha) | -0.0450841 |
| S100A10 | S100 calcium binding protein A10 | -0.0448756 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.043597 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0431564 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0429694 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0426716 |
| S100A6 | S100 calcium binding protein A6 | -0.042621 |
| RPS27A | ribosomal protein S27a | -0.0420533 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0418573 |
| RPL23 | ribosomal protein L23 | -0.0412942 |
| RPL7A | ribosomal protein L7a | -0.0409916 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.040198 |
| RPLP2 | ribosomal protein, large, P2 | -0.0401387 |
| PKM | pyruvate kinase, muscle | -0.0400976 |
| RPL9 | ribosomal protein L9 | -0.0399867 |
| RPS29 | ribosomal protein S29 | -0.0399119 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0387147 |
| RPL34 | ribosomal protein L34 | -0.0384826 |
| RPL11 | ribosomal protein L11 | -0.0376026 |
| RGS2 | regulator of G-protein signaling 2 | -0.0367756 |
| RPS3 | ribosomal protein S3 | -0.0365459 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0354852 |
| RPS27 | ribosomal protein S27 | -0.0353703 |
| RPS16 | ribosomal protein S16 | -0.0351306 |
| RPS25 | ribosomal protein S25 | -0.0350061 |
| RPL36 | ribosomal protein L36 | -0.0347734 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0347264 |
| RACK1 | receptor for activated C kinase 1 | -0.0346028 |
| RPS21 | ribosomal protein S21 | -0.0345618 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0340151 |
| RPS4X | ribosomal protein S4, X-linked | -0.0336291 |
| RPS13 | ribosomal protein S13 | -0.0335362 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0334897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0334767 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0333896 |
| NDRG1 | N-myc downstream regulated 1 | -0.0329333 |
| SRGN | serglycin | -0.0324077 |
| RPS14 | ribosomal protein S14 | -0.0319474 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0318473 |
| RPL32 | ribosomal protein L32 | -0.0317147 |
| LSAMP | limbic system-associated membrane protein | -0.0306595 |
| RPL36A | ribosomal protein L36a | -0.0305577 |
| PGK1 | phosphoglycerate kinase 1 | -0.0305269 |
| B2M | beta-2-microglobulin | -0.0303258 |
| CANX | calnexin | -0.0302161 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0296172 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0293064 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0291545 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0289877 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.028884 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0286937 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0286609 |
| RPL13A | ribosomal protein L13a | -0.0282589 |
| RPL37 | ribosomal protein L37 | -0.0280547 |
| HLA-A | major histocompatibility complex, class I, A | -0.0279191 |
| EGR1 | early growth response 1 | -0.0274932 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0271333 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0270389 |
| RPL28 | ribosomal protein L28 | -0.0270244 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0267433 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266868 |
| RPL35 | ribosomal protein L35 | -0.0264517 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0263574 |
