| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.0529863 |
| ITGAV | integrin, alpha V | 0.047896 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0419539 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0419294 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0418684 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0382147 |
| ASPH | aspartate beta-hydroxylase | 0.0382057 |
| CCNL1 | cyclin L1 | 0.0379174 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0359279 |
| ANXA1 | annexin A1 | 0.0340302 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0335963 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0312135 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0304641 |
| ARRDC3 | arrestin domain containing 3 | 0.0293287 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0291579 |
| SFTPA2 | surfactant protein A2 | 0.0287687 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0285435 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0281583 |
| MCL1 | myeloid cell leukemia 1 | 0.028028 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0279247 |
| BRD2 | bromodomain containing 2 | 0.0279221 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0278041 |
| RPL21 | ribosomal protein L21 | 0.0277483 |
| PLPP1 | phospholipid phosphatase 1 | 0.027176 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0271406 |
| SNX6 | sorting nexin 6 | 0.0265487 |
| CCDC88A | coiled-coil domain containing 88A | 0.0265024 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0264 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0260312 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0260126 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0255044 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0253756 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0253167 |
| BRD4 | bromodomain containing 4 | 0.0251447 |
| RPL37 | ribosomal protein L37 | 0.0247741 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0246657 |
| B2M | beta-2-microglobulin | 0.0246425 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.0241655 |
| KIF11 | kinesin family member 11 | 0.0240214 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0240142 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0238883 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0238857 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0238584 |
| RLIM | ring finger protein, LIM domain interacting | 0.0238159 |
| TENM3 | teneurin transmembrane protein 3 | 0.0238113 |
| RNF13 | ring finger protein 13 | 0.0237597 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236899 |
| FTL | ferritin, light polypeptide | 0.0236386 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0234915 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.023466 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0232926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0231504 |
| ITSN2 | intersectin 2 | 0.0230964 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0229923 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0228491 |
| THOC2 | THO complex 2 | 0.022466 |
| TMF1 | TATA element modulatory factor 1 | 0.0223435 |
| PARN | poly(A)-specific ribonuclease | 0.0222374 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0221518 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0219558 |
| CENPF | centromere protein F, 350/400kDa | 0.021939 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0219359 |
| YME1L1 | YME1-like 1 ATPase | 0.0219189 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0216867 |
| MICU2 | mitochondrial calcium uptake 2 | 0.021682 |
| UTRN | utrophin | 0.0216426 |
| LRRC4C | leucine rich repeat containing 4C | 0.0216103 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.0215875 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0215617 |
| HDGF | hepatoma-derived growth factor | 0.0213779 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0213601 |
| ZNF608 | zinc finger protein 608 | 0.0210599 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0209991 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0209497 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0208762 |
| TCF20 | transcription factor 20 (AR1) | 0.0208218 |
| LPIN1 | lipin 1 | 0.0203886 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0201421 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0200349 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0199916 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0199845 |
| CABIN1 | calcineurin binding protein 1 | 0.0199659 |
| FBXO42 | F-box protein 42 | 0.019941 |
| ECT2 | epithelial cell transforming 2 | 0.0198081 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0198067 |
| CNN3 | calponin 3, acidic | 0.0197098 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0195797 |
| CLCC1 | chloride channel CLIC-like 1 | 0.0194641 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.019363 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0192731 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0191615 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0191598 |
| TGFB2 | transforming growth factor, beta 2 | 0.0191541 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.0190543 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0189913 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0189744 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0189551 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0189189 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.018879 |
| ZNF618 | zinc finger protein 618 | 0.018862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.125746 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.113737 |
| ACTG1 | actin gamma 1 | -0.106434 |
| THBS1 | thrombospondin 1 | -0.0917781 |
| CADM2 | cell adhesion molecule 2 | -0.0848779 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0813601 |
| GPC3 | glypican 3 | -0.0801345 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0795562 |
| EMP1 | epithelial membrane protein 1 | -0.0729332 |
| PEG10 | paternally expressed 10 | -0.0696802 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0677414 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.067102 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0651866 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0629898 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0628297 |
| COL3A1 | collagen, type III, alpha 1 | -0.0623908 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0616921 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0579146 |
| ACTN4 | actinin, alpha 4 | -0.0565176 |
| CDK6 | cyclin-dependent kinase 6 | -0.0561587 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.055903 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0543465 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0533715 |
| ANXA2 | annexin A2 | -0.0527288 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0521214 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0517013 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0514346 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0514156 |
| NTM | neurotrimin | -0.0511957 |
| TPR | translocated promoter region, nuclear basket protein | -0.0510382 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0508703 |
| JMJD1C | jumonji domain containing 1C | -0.0499628 |
| HDAC9 | histone deacetylase 9 | -0.049135 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0462461 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0456326 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0452438 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0450287 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0449361 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0446599 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0437758 |
| DST | dystonin | -0.0431435 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0428041 |
| SRP72 | signal recognition particle 72kDa | -0.0426443 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.042003 |
| HMGB2 | high mobility group box 2 | -0.0418464 |
| RPL5 | ribosomal protein L5 | -0.0416708 |
| DEK | DEK proto-oncogene | -0.040402 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0401733 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0399742 |
| RPS16 | ribosomal protein S16 | -0.0397203 |
| COL1A2 | collagen, type I, alpha 2 | -0.0392336 |
| SEPTIN7 | septin 7 | -0.0377829 |
| ANK2 | ankyrin 2, neuronal | -0.0371137 |
| SYT1 | synaptotagmin I | -0.0364729 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0363823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0351873 |
| HMCN1 | hemicentin 1 | -0.0342312 |
| AHNAK | AHNAK nucleoprotein | -0.0342105 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.033858 |
| PCDH7 | protocadherin 7 | -0.0338171 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0336124 |
| RHEB | Ras homolog enriched in brain | -0.0332263 |
| FBL | fibrillarin | -0.0329442 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0327094 |
| RPL12 | ribosomal protein L12 | -0.032511 |
| FOXP2 | forkhead box P2 | -0.0324452 |
| MYO6 | myosin VI | -0.0324246 |
| ZFR | zinc finger RNA binding protein | -0.0322387 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0321035 |
| SPAG9 | sperm associated antigen 9 | -0.0320902 |
| FER | fer (fps/fes related) tyrosine kinase | -0.031842 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0316871 |
| RPL19 | ribosomal protein L19 | -0.0312917 |
| USP53 | ubiquitin specific peptidase 53 | -0.0310175 |
| ZNF451 | zinc finger protein 451 | -0.0310017 |
| ANXA5 | annexin A5 | -0.0303018 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0300212 |
| NUP155 | nucleoporin 155kDa | -0.0297037 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0294837 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0294223 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0290624 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0290541 |
| TEX11 | testis expressed 11 | -0.0290452 |
| BTG3 | BTG family, member 3 | -0.0290016 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0289949 |
| INTS13 | integrator complex subunit 13 | -0.0287815 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0286811 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0285421 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0284945 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0284236 |
| NF1 | neurofibromin 1 | -0.0283879 |
| IPO7 | importin 7 | -0.0282431 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0282157 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0278084 |
| TPM3 | tropomyosin 3 | -0.0277352 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0277299 |
| DACH1 | dachshund family transcription factor 1 | -0.0276365 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.027577 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.027264 |
| EVI5 | ecotropic viral integration site 5 | -0.0270824 |
