| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.169564 |
| CCNL1 | cyclin L1 | 0.0873291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0841947 |
| ZNF292 | zinc finger protein 292 | 0.082966 |
| RBM39 | RNA binding motif protein 39 | 0.0748953 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0720086 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0717806 |
| FLNB | filamin B, beta | 0.0686474 |
| GOLGA4 | golgin A4 | 0.0673586 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.065736 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0626753 |
| EZR | ezrin | 0.062599 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0619607 |
| QKI | QKI, KH domain containing, RNA binding | 0.0586862 |
| RTN4 | reticulon 4 | 0.0583325 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0554941 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0535625 |
| TXNRD1 | thioredoxin reductase 1 | 0.0527988 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0518946 |
| NUP58 | nucleoporin 58 | 0.0505356 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0502358 |
| ECT2 | epithelial cell transforming 2 | 0.048149 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0480404 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0475092 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0474233 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.046769 |
| LDHA | lactate dehydrogenase A | 0.0452934 |
| B2M | beta-2-microglobulin | 0.0448926 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.044581 |
| AHNAK | AHNAK nucleoprotein | 0.0435546 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0432607 |
| HDLBP | high density lipoprotein binding protein | 0.0431633 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0420421 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0414088 |
| SETD5 | SET domain containing 5 | 0.0413048 |
| TMEM41B | transmembrane protein 41B | 0.0412099 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0402936 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0396757 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390784 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0389193 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0388755 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0381997 |
| PRELID2 | PRELI domain containing 2 | 0.03791 |
| JMJD1C | jumonji domain containing 1C | 0.0377628 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0377137 |
| TFG | TRK-fused gene | 0.0376783 |
| RPL4 | ribosomal protein L4 | 0.0376107 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0375015 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.037093 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0369875 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0366766 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0363668 |
| RNF145 | ring finger protein 145 | 0.0358922 |
| DSTN | destrin (actin depolymerizing factor) | 0.0355706 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.035156 |
| PYGB | phosphorylase, glycogen; brain | 0.0351049 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.034447 |
| CDC73 | cell division cycle 73 | 0.0344403 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0342779 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0337498 |
| RBM25 | RNA binding motif protein 25 | 0.0333376 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0333166 |
| NBAS | neuroblastoma amplified sequence | 0.0332396 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.033116 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0329578 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0329193 |
| PTK2 | protein tyrosine kinase 2 | 0.0320084 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320075 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0319991 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0317262 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0314102 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0312119 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0310637 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0310086 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0309008 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0305235 |
| RHEB | Ras homolog enriched in brain | 0.0304164 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0302082 |
| MATR3 | matrin 3 | 0.0301631 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0301542 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0301282 |
| SLMAP | sarcolemma associated protein | 0.0296802 |
| METTL15 | methyltransferase like 15 | 0.0296058 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.029395 |
| COG5 | component of oligomeric golgi complex 5 | 0.0293254 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0292728 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0291197 |
| SPAG9 | sperm associated antigen 9 | 0.0288075 |
| DENND4A | DENN/MADD domain containing 4A | 0.0285829 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.028582 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0284338 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0283901 |
| TBC1D22A | TBC1 domain family, member 22A | 0.028346 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.028179 |
| RYBP | RING1 and YY1 binding protein | 0.0281501 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0280381 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0279554 |
| RLF | rearranged L-myc fusion | 0.0277956 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0277767 |
| EWSR1 | EWS RNA-binding protein 1 | 0.027502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151888 |
| BMP10 | bone morphogenetic protein 10 | -0.129473 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.112611 |
| FOXP1 | forkhead box P1 | -0.0983588 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0930101 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0815592 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0811965 |
| PTMA | prothymosin, alpha | -0.0633746 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0621604 |
| MKI67 | marker of proliferation Ki-67 | -0.0571347 |
| NAV2 | neuron navigator 2 | -0.0525826 |
| MYO5C | myosin VC | -0.0515635 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0472329 |
| RPS6 | ribosomal protein S6 | -0.0455048 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437581 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0416275 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0367581 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0366563 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0364063 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0359672 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0358361 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0353007 |
| CCND1 | cyclin D1 | -0.0346445 |
| RPS8 | ribosomal protein S8 | -0.0345992 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0345732 |
| S100A4 | S100 calcium binding protein A4 | -0.0338453 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0337081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0330979 |
| TUBB4B | tubulin, beta 4B class IVb | -0.03219 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0316753 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0308688 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0307051 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.030671 |
| RPL35A | ribosomal protein L35a | -0.0305609 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0303011 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0293422 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0288953 |
| MT2A | metallothionein 2A | -0.0286961 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0280225 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.027973 |
| ZNF438 | zinc finger protein 438 | -0.0279726 |
| TJP1 | tight junction protein 1 | -0.0264549 |
| CUX1 | cut-like homeobox 1 | -0.0263491 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0262966 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0258999 |
| RPL34 | ribosomal protein L34 | -0.0257239 |
| GSE1 | Gse1 coiled-coil protein | -0.0256906 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0251485 |
| RPS19 | ribosomal protein S19 | -0.0249069 |
| BMP2K | BMP2 inducible kinase | -0.0246771 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0239052 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238313 |
| FTL | ferritin, light polypeptide | -0.0236131 |
| ONECUT2 | one cut homeobox 2 | -0.0235364 |
| RPLP2 | ribosomal protein, large, P2 | -0.0235188 |
| PDE7B | phosphodiesterase 7B | -0.0234849 |
| HDAC9 | histone deacetylase 9 | -0.0232237 |
| GLI3 | GLI family zinc finger 3 | -0.0230666 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0229121 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0228591 |
| DIAPH3 | diaphanous-related formin 3 | -0.0225867 |
| TUBA1B | tubulin, alpha 1b | -0.0222667 |
| FHIT | fragile histidine triad | -0.0222037 |
| TPX2 | TPX2, microtubule-associated | -0.0220371 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0218876 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0218676 |
| RPL37A | ribosomal protein L37a | -0.0217856 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0216544 |
| ACTG1 | actin gamma 1 | -0.0215978 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0215943 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0212523 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0208381 |
| RPS13 | ribosomal protein S13 | -0.0207028 |
| THBD | thrombomodulin | -0.0205333 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0205264 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0204117 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0202269 |
| RPLP0 | ribosomal protein, large, P0 | -0.0200186 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0198185 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0198161 |
| RPS3 | ribosomal protein S3 | -0.0194375 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.019403 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0193014 |
| EMP3 | epithelial membrane protein 3 | -0.0192951 |
| RPLP1 | ribosomal protein, large, P1 | -0.0190251 |
| RIGI | RNA sensor RIG-I | -0.0189903 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0189533 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0187424 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0187317 |
| FBLN2 | fibulin 2 | -0.0187213 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0185665 |
| RPL19 | ribosomal protein L19 | -0.0183126 |
| RPS23 | ribosomal protein S23 | -0.0180143 |
| IRS1 | insulin receptor substrate 1 | -0.0177894 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0177844 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0176951 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0176 |
| GLI2 | GLI family zinc finger 2 | -0.0172986 |
| PKP4 | plakophilin 4 | -0.0172032 |
| CENPP | centromere protein P | -0.01717 |
