| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.186965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.135791 |
| VEGFA | vascular endothelial growth factor A | 0.0936829 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0916066 |
| MSN | moesin | 0.0654083 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0651261 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0617032 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0585611 |
| VCL | vinculin | 0.0550591 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0538401 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0523095 |
| NAV2 | neuron navigator 2 | 0.0508267 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0505615 |
| CCNL1 | cyclin L1 | 0.0485939 |
| FRMD4A | FERM domain containing 4A | 0.0468697 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0466382 |
| SPAG9 | sperm associated antigen 9 | 0.0460809 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0452958 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0440143 |
| DIAPH3 | diaphanous-related formin 3 | 0.0433822 |
| DST | dystonin | 0.0430854 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0405012 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0395128 |
| FN1 | fibronectin 1 | 0.039428 |
| ATP13A3 | ATPase type 13A3 | 0.0382241 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0373294 |
| SDC4 | syndecan 4 | 0.0362938 |
| HDAC9 | histone deacetylase 9 | 0.0357064 |
| RTN4 | reticulon 4 | 0.035579 |
| MYOF | myoferlin | 0.0342468 |
| MKI67 | marker of proliferation Ki-67 | 0.0336394 |
| AFDN | afadin, adherens junction formation factor | 0.033107 |
| VMP1 | vacuole membrane protein 1 | 0.0330398 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.032313 |
| GOLGA4 | golgin A4 | 0.0322828 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309983 |
| CADM1 | cell adhesion molecule 1 | 0.0307787 |
| DENND5A | DENN/MADD domain containing 5A | 0.0303633 |
| CENPF | centromere protein F, 350/400kDa | 0.0298037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295589 |
| TXNRD1 | thioredoxin reductase 1 | 0.0287549 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0286867 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0281505 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.028129 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0279436 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0278357 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0260215 |
| FNIP1 | folliculin interacting protein 1 | 0.0260212 |
| JMJD1C | jumonji domain containing 1C | 0.0259952 |
| FLNA | filamin A, alpha | 0.0258293 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0250422 |
| RLIM | ring finger protein, LIM domain interacting | 0.0247026 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0242106 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0241773 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0240643 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0238289 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.023711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232774 |
| WDR43 | WD repeat domain 43 | 0.0232718 |
| COPA | coatomer protein complex, subunit alpha | 0.0232439 |
| CKAP5 | cytoskeleton associated protein 5 | 0.023227 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232064 |
| CREBRF | CREB3 regulatory factor | 0.0231463 |
| PGM3 | phosphoglucomutase 3 | 0.0227943 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0226112 |
| OGA | O-GlcNAcase | 0.0223725 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0223666 |
| NEK7 | NIMA-related kinase 7 | 0.022324 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0221229 |
| TPM3 | tropomyosin 3 | 0.0221005 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.021953 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0216435 |
| POTEF | POTE ankyrin domain family, member F | 0.0215808 |
| WTAP | Wilms tumor 1 associated protein | 0.0211176 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.02109 |
| PRELID2 | PRELI domain containing 2 | 0.0209667 |
| USP47 | ubiquitin specific peptidase 47 | 0.0209508 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0209272 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0208282 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0208206 |
| SETD5 | SET domain containing 5 | 0.0207224 |
| NCKAP1 | NCK-associated protein 1 | 0.0206964 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0206348 |
| ANO6 | anoctamin 6 | 0.0204695 |
| USP12 | ubiquitin specific peptidase 12 | 0.0204217 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.020389 |
| YTHDC1 | YTH domain containing 1 | 0.0203651 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0202468 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.020201 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0201877 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0200706 |
| CRY1 | cryptochrome circadian clock 1 | 0.0199622 |
| FRMD5 | FERM domain containing 5 | 0.0199337 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0198266 |
| RANBP9 | RAN binding protein 9 | 0.0197131 |
| CALD1 | caldesmon 1 | 0.0196552 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0195123 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0194226 |
| OPTN | optineurin | 0.0194046 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0192438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.265878 |
| VIM | vimentin | -0.244941 |
| FTL | ferritin, light polypeptide | -0.138487 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11999 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.116518 |
| IER3 | immediate early response 3 | -0.107488 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.100479 |
| MT2A | metallothionein 2A | -0.0874998 |
| NDRG1 | N-myc downstream regulated 1 | -0.0850009 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0841918 |
| RPS6 | ribosomal protein S6 | -0.0807617 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0775134 |
| HLA-B | major histocompatibility complex, class I, B | -0.0722068 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.069605 |
| CD44 | CD44 molecule (Indian blood group) | -0.0683686 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0668772 |
| HLA-A | major histocompatibility complex, class I, A | -0.0639383 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0638365 |
| BICC1 | BicC family RNA binding protein 1 | -0.0624513 |
| GLIS3 | GLIS family zinc finger 3 | -0.0613282 |
| TMSB10 | thymosin beta 10 | -0.0595989 |
| RPS8 | ribosomal protein S8 | -0.0573665 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0570188 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0570019 |
| RAI14 | retinoic acid induced 14 | -0.0563121 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.055781 |
| ENO1 | enolase 1, (alpha) | -0.0534222 |
| RPLP1 | ribosomal protein, large, P1 | -0.0532267 |
| CANX | calnexin | -0.052617 |
| RPL12 | ribosomal protein L12 | -0.0498891 |
| RPS24 | ribosomal protein S24 | -0.0478066 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0462651 |
| PGK1 | phosphoglycerate kinase 1 | -0.0460062 |
| ANXA2 | annexin A2 | -0.0453603 |
| RPLP0 | ribosomal protein, large, P0 | -0.0453276 |
| GNAS | GNAS complex locus | -0.0437911 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0436954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.043087 |
| SLC38A1 | solute carrier family 38, member 1 | -0.042687 |
| SQSTM1 | sequestosome 1 | -0.0426628 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0424887 |
| ADM | adrenomedullin | -0.0423924 |
| ACTG1 | actin gamma 1 | -0.0422292 |
| STC1 | stanniocalcin 1 | -0.0420366 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.041883 |
| PLIN2 | perilipin 2 | -0.0417777 |
| RPL36A | ribosomal protein L36a | -0.0412853 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0409731 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0408683 |
| RACK1 | receptor for activated C kinase 1 | -0.0396736 |
| RPL35A | ribosomal protein L35a | -0.0389362 |
| RPL37A | ribosomal protein L37a | -0.0388576 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0384351 |
| RPL19 | ribosomal protein L19 | -0.0383682 |
| RPS23 | ribosomal protein S23 | -0.038094 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0380039 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0378322 |
| LDHA | lactate dehydrogenase A | -0.0363442 |
| LOX | lysyl oxidase | -0.0363396 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0363034 |
| RPS13 | ribosomal protein S13 | -0.0359713 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.035869 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0357338 |
| RPS12 | ribosomal protein S12 | -0.0356435 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350525 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0349025 |
| RPL7A | ribosomal protein L7a | -0.0348854 |
| HLA-E | major histocompatibility complex, class I, E | -0.033922 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0334134 |
| RPS3 | ribosomal protein S3 | -0.0321737 |
| RPL31 | ribosomal protein L31 | -0.0320899 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0311774 |
| CTSB | cathepsin B | -0.0308328 |
| RPL37 | ribosomal protein L37 | -0.0305786 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0304348 |
| RPS19 | ribosomal protein S19 | -0.0303514 |
| RPL27A | ribosomal protein L27a | -0.0302911 |
| RPL5 | ribosomal protein L5 | -0.0302351 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0301921 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0300812 |
| RPS27A | ribosomal protein S27a | -0.0300282 |
| CAVIN1 | caveolae associated protein 1 | -0.0297211 |
| RPS10 | ribosomal protein S10 | -0.0296676 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0294206 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286924 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0286131 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0283884 |
| TXNIP | thioredoxin interacting protein | -0.0283688 |
| RPS29 | ribosomal protein S29 | -0.0280167 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0279697 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279611 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0275442 |
| RPL32 | ribosomal protein L32 | -0.0274582 |
| CTSD | cathepsin D | -0.0274095 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0273275 |
| RPS4X | ribosomal protein S4, X-linked | -0.0273037 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0272587 |
| FOXP1 | forkhead box P1 | -0.027258 |
| RPL35 | ribosomal protein L35 | -0.0270613 |
| RPL36 | ribosomal protein L36 | -0.0268628 |
