| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0938689 |
| B2M | beta-2-microglobulin | 0.083461 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0828684 |
| VEGFA | vascular endothelial growth factor A | 0.07784 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0704698 |
| CALR | calreticulin | 0.0587297 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0558795 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0555969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0526571 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0473475 |
| TMSB4X | thymosin beta 4, X-linked | 0.0472872 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0462983 |
| PGK1 | phosphoglycerate kinase 1 | 0.0449267 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0440918 |
| COG5 | component of oligomeric golgi complex 5 | 0.0426851 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0422493 |
| JAK1 | Janus kinase 1 | 0.0420873 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.041939 |
| PAPOLA | poly(A) polymerase alpha | 0.0415305 |
| CDH13 | cadherin 13 | 0.0415178 |
| ATP13A3 | ATPase type 13A3 | 0.0411877 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0399037 |
| SBF2 | SET binding factor 2 | 0.0389059 |
| TPM3 | tropomyosin 3 | 0.037973 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.03662 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0364326 |
| OPTN | optineurin | 0.0361471 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0355827 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0351012 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0349484 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0344223 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0343122 |
| PLEC | plectin | 0.0340172 |
| GOLGA4 | golgin A4 | 0.0336551 |
| SETD5 | SET domain containing 5 | 0.0334141 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0333621 |
| YBX1 | Y box binding protein 1 | 0.0332031 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0316638 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0315034 |
| VCAN | versican | 0.030964 |
| NAV1 | neuron navigator 1 | 0.0307361 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0298629 |
| STK17B | serine/threonine kinase 17b | 0.0295864 |
| UBQLN1 | ubiquilin 1 | 0.0291142 |
| RNF145 | ring finger protein 145 | 0.0290093 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0289092 |
| RPS12 | ribosomal protein S12 | 0.0287016 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0286488 |
| FOXJ3 | forkhead box J3 | 0.0285854 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0285116 |
| XPO1 | exportin 1 | 0.028435 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0282409 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0280831 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0280211 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.027942 |
| DIDO1 | death inducer-obliterator 1 | 0.0278167 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0274545 |
| COG6 | component of oligomeric golgi complex 6 | 0.027391 |
| MORF4L1 | mortality factor 4 like 1 | 0.027274 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0270599 |
| CCNL1 | cyclin L1 | 0.0269766 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0267795 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0265445 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0261604 |
| MORF4L2 | mortality factor 4 like 2 | 0.0260607 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0260135 |
| COPA | coatomer protein complex, subunit alpha | 0.026006 |
| HYOU1 | hypoxia up-regulated 1 | 0.0259456 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0258861 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0257379 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0256015 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0255748 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0255505 |
| TMEM167A | transmembrane protein 167A | 0.0254966 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0254742 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0254509 |
| LAMB1 | laminin, beta 1 | 0.0251975 |
| FAM13B | family with sequence similarity 13, member B | 0.0251329 |
| NOP58 | NOP58 ribonucleoprotein | 0.0251235 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0250793 |
| TPM1 | tropomyosin 1 (alpha) | 0.0249983 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.024978 |
| ADAR | adenosine deaminase, RNA-specific | 0.0249016 |
| SETX | senataxin | 0.0248879 |
| SCFD2 | sec1 family domain containing 2 | 0.0247118 |
| KIAA0319L | KIAA0319-like | 0.0246352 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.0245522 |
| EMP1 | epithelial membrane protein 1 | 0.0245356 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.024531 |
| C5ORF15 | chromosome 5 open reading frame 15 | 0.024495 |
| YIPF5 | Yip1 domain family, member 5 | 0.0243925 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0242869 |
| NGLY1 | N-glycanase 1 | 0.0241832 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0236319 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0236109 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.023451 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0233877 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0233582 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0233291 |
| ZNF146 | zinc finger protein 146 | 0.0232174 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.361947 |
| TMSB10 | thymosin beta 10 | -0.115865 |
| MT2A | metallothionein 2A | -0.114495 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.101305 |
| UBC | ubiquitin C | -0.094432 |
| LOX | lysyl oxidase | -0.0915763 |
| FN1 | fibronectin 1 | -0.0769922 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0667805 |
| SDC4 | syndecan 4 | -0.0612127 |
| SRPK2 | SRSF protein kinase 2 | -0.0596625 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0595461 |
| MEF2A | myocyte enhancer factor 2A | -0.0592985 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0580787 |
| CCNI | cyclin I | -0.0556792 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0540664 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0517328 |
| IL6 | interleukin 6 | -0.0503478 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0499342 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0498581 |
| ANXA5 | annexin A5 | -0.0472602 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0471068 |
| TXNIP | thioredoxin interacting protein | -0.0467475 |
| COL1A1 | collagen, type I, alpha 1 | -0.0454868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0450438 |
| ZNF395 | zinc finger protein 395 | -0.0435978 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0433267 |
| ENO1 | enolase 1, (alpha) | -0.043318 |
| STC1 | stanniocalcin 1 | -0.0432143 |
| NDRG1 | N-myc downstream regulated 1 | -0.0418359 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0409747 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0405846 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0400793 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0400113 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0394915 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0394703 |
| HIP1 | huntingtin interacting protein 1 | -0.0394679 |
| SPAG9 | sperm associated antigen 9 | -0.0393678 |
| SEPTIN7 | septin 7 | -0.0390483 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0388937 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0372907 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0371165 |
| FLNA | filamin A, alpha | -0.0364838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.035832 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0356507 |
| VCL | vinculin | -0.035509 |
| AHR | aryl hydrocarbon receptor | -0.0349622 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0348302 |
| VIM | vimentin | -0.0347732 |
| PRSS23 | protease, serine, 23 | -0.034169 |
| GLIS3 | GLIS family zinc finger 3 | -0.0341302 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0336569 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0336177 |
| OSMR | oncostatin M receptor | -0.0331522 |
| PCM1 | pericentriolar material 1 | -0.0321987 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0320098 |
| PRELID2 | PRELI domain containing 2 | -0.03199 |
| EXOC4 | exocyst complex component 4 | -0.0319714 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318319 |
| NRP1 | neuropilin 1 | -0.0317682 |
| CLTC | clathrin, heavy chain (Hc) | -0.0317245 |
| PALLD | palladin, cytoskeletal associated protein | -0.0314738 |
| CDK6 | cyclin-dependent kinase 6 | -0.0314069 |
| CCDC88A | coiled-coil domain containing 88A | -0.0312282 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0308248 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.030614 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0304008 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0303692 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0302213 |
| ZNF207 | zinc finger protein 207 | -0.0301416 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0301394 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0301053 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0300257 |
| AHNAK | AHNAK nucleoprotein | -0.0299028 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0294994 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0293847 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0292543 |
| OGA | O-GlcNAcase | -0.0289843 |
| MT1X | metallothionein 1X | -0.0286736 |
| EFNA5 | ephrin-A5 | -0.0285524 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0285413 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0284856 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.028278 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0281285 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0280945 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0279758 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0279551 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0277232 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0277069 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0275128 |
| SETBP1 | SET binding protein 1 | -0.0273237 |
| THOC2 | THO complex 2 | -0.027316 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0270502 |
| RPS6 | ribosomal protein S6 | -0.0269925 |
| IL6ST | interleukin 6 signal transducer | -0.0266305 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0265203 |
| FBN1 | fibrillin 1 | -0.0264591 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.0264407 |
| RTN4 | reticulon 4 | -0.0263014 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0261698 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0260363 |
