| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lucanthone perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lucanthone_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0493727 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0471873 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0461793 |
| TMSB4X | thymosin beta 4, X-linked | 0.0452358 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0394296 |
| FAT1 | FAT atypical cadherin 1 | 0.0385647 |
| GPC6 | glypican 6 | 0.03818 |
| RPL4 | ribosomal protein L4 | 0.0354982 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0348693 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.034767 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0347443 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0342009 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0325058 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0308475 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295405 |
| RBM39 | RNA binding motif protein 39 | 0.0294268 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0293184 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0286736 |
| SMOX | spermine oxidase | 0.0285197 |
| DST | dystonin | 0.0285153 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0277397 |
| PNN | pinin, desmosome associated protein | 0.0271771 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0268333 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266365 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.026544 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.026423 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0261454 |
| SDC4 | syndecan 4 | 0.0261174 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0258602 |
| WDR43 | WD repeat domain 43 | 0.0252089 |
| CD44 | CD44 molecule (Indian blood group) | 0.02477 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0245642 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0242725 |
| YME1L1 | YME1-like 1 ATPase | 0.0242647 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0240266 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0223437 |
| ANXA5 | annexin A5 | 0.0223083 |
| RNF145 | ring finger protein 145 | 0.0222411 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0217728 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.021296 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0212743 |
| RLIM | ring finger protein, LIM domain interacting | 0.0210728 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0210353 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0209404 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0205982 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0203855 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0203374 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0200139 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0199169 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0197204 |
| IFRD1 | interferon-related developmental regulator 1 | 0.019476 |
| RAB18 | RAB18, member RAS oncogene family | 0.019238 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0191171 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0188416 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0187962 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0186453 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0185915 |
| NBAS | neuroblastoma amplified sequence | 0.0185846 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0185772 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0185432 |
| TPM3 | tropomyosin 3 | 0.0183345 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0182364 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0182047 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0180725 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0179808 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0179578 |
| ZNF292 | zinc finger protein 292 | 0.0179187 |
| EZR | ezrin | 0.0178553 |
| RAB1A | RAB1A, member RAS oncogene family | 0.017776 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0177612 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0176029 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0174576 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0174374 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0173358 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0172906 |
| SRFBP1 | serum response factor binding protein 1 | 0.0171746 |
| PGK1 | phosphoglycerate kinase 1 | 0.0171475 |
| DNMBP | dynamin binding protein | 0.0171217 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0169742 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0168405 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0168124 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0167473 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0166522 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0166472 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.0165878 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0165842 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0165611 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0165608 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0164893 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0164592 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0164426 |
| PRELID2 | PRELI domain containing 2 | 0.0164201 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0163889 |
| RBM25 | RNA binding motif protein 25 | 0.016368 |
| CCNL1 | cyclin L1 | 0.0163503 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0162881 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0161898 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0160932 |
| RPL23 | ribosomal protein L23 | 0.0159972 |
| CRY1 | cryptochrome circadian clock 1 | 0.0159823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.444451 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.216091 |
| FN1 | fibronectin 1 | -0.132034 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.124626 |
| NDRG1 | N-myc downstream regulated 1 | -0.110803 |
| SYT1 | synaptotagmin I | -0.0848018 |
| SQSTM1 | sequestosome 1 | -0.0810593 |
| TXNIP | thioredoxin interacting protein | -0.0787173 |
| NRG1 | neuregulin 1 | -0.0717617 |
| NRP1 | neuropilin 1 | -0.0699244 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0658426 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0650918 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0605169 |
| FTL | ferritin, light polypeptide | -0.0593024 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0586738 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0530845 |
| PLIN2 | perilipin 2 | -0.0518031 |
| NTN4 | netrin 4 | -0.0486097 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.048222 |
| EFNA5 | ephrin-A5 | -0.0467847 |
| MT2A | metallothionein 2A | -0.0466343 |
| CD109 | CD109 molecule | -0.0444619 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0443418 |
| FNBP1 | formin binding protein 1 | -0.0395962 |
| OSMR | oncostatin M receptor | -0.0389288 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0389267 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0377387 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0375414 |
| HPCAL1 | hippocalcin-like 1 | -0.0370912 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0369934 |
| STC2 | stanniocalcin 2 | -0.0364468 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0362943 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0362618 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0361121 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0358555 |
| VCL | vinculin | -0.0355508 |
| MAP1B | microtubule-associated protein 1B | -0.0351866 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0350874 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0350491 |
| AEBP2 | AE binding protein 2 | -0.0348645 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0348503 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0339562 |
| SFTPA2 | surfactant protein A2 | -0.0339115 |
| FNDC3A | fibronectin type III domain containing 3A | -0.033807 |
| SSH1 | slingshot protein phosphatase 1 | -0.0335902 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0331966 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.032712 |
| HMGB3 | high mobility group box 3 | -0.032642 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0321405 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0318554 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0309284 |
| KSR1 | kinase suppressor of ras 1 | -0.0302665 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0298235 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0296697 |
| H1-0 | H1.0 linker histone | -0.0294064 |
| MKI67 | marker of proliferation Ki-67 | -0.0294057 |
| B2M | beta-2-microglobulin | -0.0293048 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0292342 |
| GLUL | glutamate-ammonia ligase | -0.0290184 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0289178 |
| TMSB10 | thymosin beta 10 | -0.028874 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0286203 |
| RORA | RAR-related orphan receptor A | -0.0285995 |
| PKM | pyruvate kinase, muscle | -0.0284441 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0281143 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0280964 |
| ITGA1 | integrin, alpha 1 | -0.0280791 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0279525 |
| ETV1 | ets variant 1 | -0.0278998 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0278522 |
| CENPF | centromere protein F, 350/400kDa | -0.027734 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0275623 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275587 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0275094 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0274653 |
| MTDH | metadherin | -0.0269731 |
| SLC38A2 | solute carrier family 38, member 2 | -0.026461 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0263925 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0262693 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0261733 |
| TXNRD1 | thioredoxin reductase 1 | -0.0261236 |
| PPARA | peroxisome proliferator-activated receptor alpha | -0.0258144 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0256584 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0256416 |
| ATP11A | ATPase, class VI, type 11A | -0.025465 |
| EGR1 | early growth response 1 | -0.025338 |
| GPATCH2L | G patch domain containing 2-like | -0.0252463 |
| RASAL2 | RAS protein activator like 2 | -0.0251616 |
| RAB10 | RAB10, member RAS oncogene family | -0.0250639 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0248713 |
| BPTF | bromodomain PHD finger transcription factor | -0.0246663 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0246288 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0242928 |
| TPR | translocated promoter region, nuclear basket protein | -0.0242687 |
| RANBP17 | RAN binding protein 17 | -0.0242338 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0241455 |
| CDK13 | cyclin-dependent kinase 13 | -0.0240881 |
| PRKCA | protein kinase C, alpha | -0.0239914 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0238244 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0237493 |
