| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.220071 |
| VMP1 | vacuole membrane protein 1 | 0.0878315 |
| INTS6 | integrator complex subunit 6 | 0.0737814 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0641938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.060814 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0578929 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0571006 |
| MCL1 | myeloid cell leukemia 1 | 0.0559244 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0449985 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0420894 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0401846 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0399053 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0394323 |
| PLSCR2 | phospholipid scramblase 2 | 0.0380181 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.037951 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0377986 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0374204 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0369593 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0362953 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0358129 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0349274 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0341567 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0341019 |
| FNBP1L | formin binding protein 1-like | 0.0340256 |
| MED13 | mediator complex subunit 13 | 0.0333116 |
| FAM168A | family with sequence similarity 168, member A | 0.0320059 |
| STXBP4 | syntaxin binding protein 4 | 0.0317429 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0312609 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0306438 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302331 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0301126 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0299738 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0298356 |
| DTNA | dystrobrevin, alpha | 0.0296466 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293209 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0285438 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0283081 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0269122 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0268839 |
| RCOR1 | REST corepressor 1 | 0.0268796 |
| NEK7 | NIMA-related kinase 7 | 0.0267387 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0266197 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0264803 |
| KRT86 | keratin 86, type II | 0.0263173 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0258132 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0257331 |
| HOMER1 | homer scaffolding protein 1 | 0.0255211 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0252083 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0250489 |
| CUL3 | cullin 3 | 0.0250474 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.02493 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0248839 |
| SQSTM1 | sequestosome 1 | 0.0245388 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0235786 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0235399 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0233874 |
| RPS12 | ribosomal protein S12 | 0.0233512 |
| ADIPOR2 | adiponectin receptor 2 | 0.0230066 |
| VCP | valosin containing protein | 0.0228662 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0224495 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0224205 |
| ENAH | enabled homolog (Drosophila) | 0.0223365 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0222497 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0221872 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.021797 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.021794 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0217287 |
| ACTN4 | actinin, alpha 4 | 0.0216526 |
| UBAP1 | ubiquitin associated protein 1 | 0.0216304 |
| RPS3 | ribosomal protein S3 | 0.0216039 |
| DENND5A | DENN/MADD domain containing 5A | 0.0211999 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0209888 |
| FOXJ3 | forkhead box J3 | 0.0209048 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0207753 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0207714 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0205374 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0204472 |
| SRPK2 | SRSF protein kinase 2 | 0.0204157 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203576 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0201529 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0200826 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0199945 |
| FOXO3 | forkhead box O3 | 0.019958 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0197735 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0195265 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193377 |
| EFNA5 | ephrin-A5 | 0.0193288 |
| FBXO11 | F-box protein 11 | 0.0192745 |
| SLMAP | sarcolemma associated protein | 0.0191142 |
| ZNF638 | zinc finger protein 638 | 0.0186635 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.018606 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0184705 |
| MYO1D | myosin ID | 0.018453 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0183859 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0182218 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0181327 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0180707 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0177412 |
| ZNF207 | zinc finger protein 207 | 0.0177048 |
| MRTFA | myocardin related transcription factor A | 0.0176705 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.214257 |
| RPL19 | ribosomal protein L19 | -0.0910967 |
| LASP1 | LIM and SH3 protein 1 | -0.0864712 |
| CCND1 | cyclin D1 | -0.0712297 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0696284 |
| TMSB4X | thymosin beta 4, X-linked | -0.0692264 |
| ACTG1 | actin gamma 1 | -0.0621945 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0603769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0580476 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0569417 |
| PTMA | prothymosin, alpha | -0.0535929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0502366 |
| DSPP | dentin sialophosphoprotein | -0.0502087 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0483234 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0474234 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0470151 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0463791 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0451731 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.042277 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0416372 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0403219 |
| DSTN | destrin (actin depolymerizing factor) | -0.0398339 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0396774 |
| OSMR | oncostatin M receptor | -0.0393615 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0387443 |
| AHNAK | AHNAK nucleoprotein | -0.0379987 |
| ASPH | aspartate beta-hydroxylase | -0.0375315 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0346103 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0335482 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0332829 |
| TMSB10 | thymosin beta 10 | -0.0325216 |
| S100A6 | S100 calcium binding protein A6 | -0.0324723 |
| PFDN4 | prefoldin subunit 4 | -0.0322262 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310325 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0308667 |
| RPL35A | ribosomal protein L35a | -0.0307915 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0303053 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0301932 |
| GOLGA4 | golgin A4 | -0.0301135 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.029536 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0294649 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0292645 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0290335 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0290097 |
| H1-0 | H1.0 linker histone | -0.0288016 |
| TMEM123 | transmembrane protein 123 | -0.0285032 |
| RRBP1 | ribosome binding protein 1 | -0.0272841 |
| TMEM165 | transmembrane protein 165 | -0.0272034 |
| CCNI | cyclin I | -0.0271299 |
| KRT7 | keratin 7, type II | -0.0270603 |
| RAD21 | RAD21 homolog (S. pombe) | -0.026776 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0267127 |
| TPM4 | tropomyosin 4 | -0.0265182 |
| LMNA | lamin A/C | -0.0264324 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.026141 |
| RPL34 | ribosomal protein L34 | -0.0257312 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0256333 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0254567 |
| PRR11 | proline rich 11 | -0.0248915 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0247511 |
| HLA-B | major histocompatibility complex, class I, B | -0.0246445 |
| TMEM45B | transmembrane protein 45B | -0.0245732 |
| TMC5 | transmembrane channel-like 5 | -0.024526 |
| GATA3 | GATA binding protein 3 | -0.0243103 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0242426 |
| DSG2 | desmoglein 2 | -0.0238496 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0237994 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.023203 |
| CUX1 | cut-like homeobox 1 | -0.0229468 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0228304 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.022746 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0226293 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0226136 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0225512 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0225015 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0224017 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0222679 |
| KRT19 | keratin 19, type I | -0.0220335 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219838 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0216875 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0215909 |
| CBX3 | chromobox homolog 3 | -0.0213649 |
| DEK | DEK proto-oncogene | -0.0213227 |
| DUSP4 | dual specificity phosphatase 4 | -0.0212535 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0209145 |
| S100A9 | S100 calcium binding protein A9 | -0.0208936 |
| TMEM263 | transmembrane protein 263 | -0.0208526 |
| CALU | calumenin | -0.0206942 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0206736 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0205459 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0201413 |
| ZNF652 | zinc finger protein 652 | -0.0200825 |
| CANX | calnexin | -0.0197517 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0196904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0196288 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0194987 |
| RPL23 | ribosomal protein L23 | -0.0194315 |
| EGFR | epidermal growth factor receptor | -0.0194267 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0193557 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0193263 |
