| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF608 | zinc finger protein 608 | 0.0978494 |
| DST | dystonin | 0.0779396 |
| VCL | vinculin | 0.067364 |
| JMJD1C | jumonji domain containing 1C | 0.0596872 |
| COL5A2 | collagen, type V, alpha 2 | 0.0535732 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0530276 |
| PCBP2 | poly(rC) binding protein 2 | 0.0450819 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0450807 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0441809 |
| VMP1 | vacuole membrane protein 1 | 0.039895 |
| WLS | wntless Wnt ligand secretion mediator | 0.039507 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0392381 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0391408 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0382968 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0371768 |
| SFPQ | splicing factor proline/glutamine-rich | 0.036318 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0360322 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0358659 |
| NFIB | nuclear factor I/B | 0.0358394 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0356715 |
| RIGI | RNA sensor RIG-I | 0.0347081 |
| CABIN1 | calcineurin binding protein 1 | 0.0346065 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0344826 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0338242 |
| INTS6 | integrator complex subunit 6 | 0.0332261 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0331401 |
| EFNA5 | ephrin-A5 | 0.0330792 |
| SMYD3 | SET and MYND domain containing 3 | 0.0329988 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0323363 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0320786 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0318407 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0316693 |
| MED13 | mediator complex subunit 13 | 0.0312562 |
| PRELID2 | PRELI domain containing 2 | 0.0309497 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.030817 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0296935 |
| FNDC3B | fibronectin type III domain containing 3B | 0.029371 |
| MCL1 | myeloid cell leukemia 1 | 0.0288056 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0281451 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0275019 |
| DIDO1 | death inducer-obliterator 1 | 0.0267372 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0264132 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.025518 |
| ZNF638 | zinc finger protein 638 | 0.0253256 |
| MED13L | mediator complex subunit 13-like | 0.0252796 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0252076 |
| AUTS2 | autism susceptibility candidate 2 | 0.0250547 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0248334 |
| TOX | thymocyte selection-associated high mobility group box | 0.0247137 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0246167 |
| BRD4 | bromodomain containing 4 | 0.0246022 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0244596 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0244293 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0241019 |
| ANK2 | ankyrin 2, neuronal | 0.0239314 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0237289 |
| ZNF644 | zinc finger protein 644 | 0.0236692 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0234761 |
| PRKCE | protein kinase C, epsilon | 0.02345 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234389 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0233557 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0231545 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0228809 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0228565 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0228036 |
| SERTAD2 | SERTA domain containing 2 | 0.0225866 |
| ASPH | aspartate beta-hydroxylase | 0.0225254 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0224696 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0224464 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0222074 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0221986 |
| EGR1 | early growth response 1 | 0.0221188 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0220998 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0219191 |
| CPNE1 | copine I | 0.0218773 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0217724 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217703 |
| RCC1 | regulator of chromosome condensation 1 | 0.0216553 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0215914 |
| NRDC | nardilysin convertase | 0.0215626 |
| POTEF | POTE ankyrin domain family, member F | 0.021542 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0215249 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0214405 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0211885 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0210551 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0205511 |
| DENND5A | DENN/MADD domain containing 5A | 0.0204985 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0202657 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0202087 |
| LATS2 | large tumor suppressor kinase 2 | 0.0201636 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201041 |
| NBEAL1 | neurobeachin-like 1 | 0.0196376 |
| HHIP | hedgehog interacting protein | 0.0196102 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0194813 |
| PHF21A | PHD finger protein 21A | 0.0191311 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0190395 |
| MYO1E | myosin IE | 0.0189791 |
| SQSTM1 | sequestosome 1 | 0.0188448 |
| ATG10 | autophagy related 10 | 0.0187894 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0187786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.15741 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.132012 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.117183 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0983178 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0946101 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0908278 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0709205 |
| CADM2 | cell adhesion molecule 2 | -0.0688285 |
| RPL11 | ribosomal protein L11 | -0.0678208 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0672349 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0611807 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0610733 |
| RPS21 | ribosomal protein S21 | -0.0590842 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0555191 |
| RPS24 | ribosomal protein S24 | -0.053406 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0518758 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0505182 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0500091 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0483846 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0477497 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476076 |
| LDHA | lactate dehydrogenase A | -0.0460061 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0459768 |
| TMSB10 | thymosin beta 10 | -0.0459034 |
| RPL34 | ribosomal protein L34 | -0.0438155 |
| PTMA | prothymosin, alpha | -0.0434514 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0422939 |
| RAD51B | RAD51 paralog B | -0.0412418 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0410965 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.040571 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0402929 |
| GAB2 | GRB2-associated binding protein 2 | -0.0401083 |
| ENO1 | enolase 1, (alpha) | -0.0396249 |
| RPS6 | ribosomal protein S6 | -0.0390999 |
| RPL26 | ribosomal protein L26 | -0.0378598 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0377668 |
| RPL12 | ribosomal protein L12 | -0.0374602 |
| RPL30 | ribosomal protein L30 | -0.0364294 |
| GNAS | GNAS complex locus | -0.0357385 |
| RPLP0 | ribosomal protein, large, P0 | -0.0347022 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0346324 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0343814 |
| RHOA | ras homolog family member A | -0.0329986 |
| HMGB1 | high mobility group box 1 | -0.0329569 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0329178 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0320097 |
| DEK | DEK proto-oncogene | -0.0318052 |
| RBM25 | RNA binding motif protein 25 | -0.0315409 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.031408 |
| RPL19 | ribosomal protein L19 | -0.0306606 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0305203 |
| RPS12 | ribosomal protein S12 | -0.0300314 |
| RPL18 | ribosomal protein L18 | -0.0293805 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0292389 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0280133 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.027468 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.027277 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0268826 |
| MKI67 | marker of proliferation Ki-67 | -0.0264976 |
| NEBL | nebulette | -0.0263636 |
| TUBB | tubulin, beta class I | -0.0263137 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0263103 |
| CENPE | centromere protein E, 312kDa | -0.0263037 |
| CDH18 | cadherin 18, type 2 | -0.026273 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0262001 |
| CANX | calnexin | -0.0261823 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0259396 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.025922 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.025694 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0256827 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0255203 |
| SALL4 | spalt-like transcription factor 4 | -0.0253615 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0253485 |
| PFN1 | profilin 1 | -0.0252349 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0247522 |
| EMP1 | epithelial membrane protein 1 | -0.0241846 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.024132 |
| WDR43 | WD repeat domain 43 | -0.0241203 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0239647 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0235854 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0235123 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.023486 |
| WDR45B | WD repeat domain 45B | -0.0234263 |
| RPL36A | ribosomal protein L36a | -0.0233154 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0232492 |
| RPL32 | ribosomal protein L32 | -0.0231828 |
| RPLP1 | ribosomal protein, large, P1 | -0.022878 |
| H3-3B | H3.3 histone B | -0.0226854 |
| ZNF217 | zinc finger protein 217 | -0.0226686 |
| CENPF | centromere protein F, 350/400kDa | -0.0225306 |
| RPL23 | ribosomal protein L23 | -0.0223017 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0222859 |
| TMX3 | thioredoxin-related transmembrane protein 3 | -0.0222597 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0221486 |
| RPS17 | ribosomal protein S17 | -0.0219446 |
| NUP107 | nucleoporin 107kDa | -0.0218526 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0216542 |
| RPL4 | ribosomal protein L4 | -0.0215693 |
| YY1 | YY1 transcription factor | -0.0215482 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0215332 |
