| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.174922 |
| FMN1 | formin 1 | 0.138373 |
| LSAMP | limbic system-associated membrane protein | 0.136756 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0949203 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0851645 |
| NRG1 | neuregulin 1 | 0.0824562 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0773921 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0688615 |
| TLE4 | transducin-like enhancer of split 4 | 0.0665082 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0616151 |
| DST | dystonin | 0.0602169 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0583987 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0540951 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0537007 |
| PRKCA | protein kinase C, alpha | 0.0512132 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0496738 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0479908 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0474128 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0446231 |
| TPM4 | tropomyosin 4 | 0.0445315 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0428733 |
| SMYD3 | SET and MYND domain containing 3 | 0.0425226 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0411775 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0403366 |
| SIK2 | salt-inducible kinase 2 | 0.040214 |
| AHR | aryl hydrocarbon receptor | 0.0397627 |
| FN1 | fibronectin 1 | 0.0397424 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.039574 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0387634 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.038274 |
| AUTS2 | autism susceptibility candidate 2 | 0.0379901 |
| TPM1 | tropomyosin 1 (alpha) | 0.0371571 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0369932 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0367659 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0366697 |
| DNM3 | dynamin 3 | 0.0363245 |
| RNF213 | ring finger protein 213 | 0.0359471 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0354622 |
| NREP | neuronal regeneration related protein | 0.035246 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0351992 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0343228 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0341183 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0337289 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0335067 |
| ATXN1 | ataxin 1 | 0.0330526 |
| JMJD1C | jumonji domain containing 1C | 0.0328201 |
| ATM | ATM serine/threonine kinase | 0.0326745 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0326255 |
| FERMT2 | fermitin family member 2 | 0.0325082 |
| SCG2 | secretogranin II | 0.0322465 |
| RAD51B | RAD51 paralog B | 0.0316538 |
| KLHL13 | kelch-like family member 13 | 0.0308444 |
| ATRNL1 | attractin-like 1 | 0.0304091 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0300396 |
| TENM4 | teneurin transmembrane protein 4 | 0.0300373 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0295473 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0288791 |
| RIGI | RNA sensor RIG-I | 0.0286046 |
| PLAT | plasminogen activator, tissue | 0.028505 |
| SPOP | speckle-type POZ protein | 0.0282936 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0282849 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0282245 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.02803 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0279995 |
| MX2 | MX dynamin-like GTPase 2 | 0.0279736 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0279453 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0278117 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0277559 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0277387 |
| GPATCH8 | G patch domain containing 8 | 0.0275048 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0272591 |
| VMP1 | vacuole membrane protein 1 | 0.0272145 |
| LIMA1 | LIM domain and actin binding 1 | 0.0266735 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.026505 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0264873 |
| BBX | bobby sox homolog (Drosophila) | 0.0264486 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0263859 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0263674 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0263537 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0263319 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0262438 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0260661 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0260437 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0259171 |
| ZNF124 | zinc finger protein 124 | 0.0251982 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.02509 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0250601 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0247813 |
| SETBP1 | SET binding protein 1 | 0.0247579 |
| CTSB | cathepsin B | 0.0245003 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0244957 |
| MTAP | methylthioadenosine phosphorylase | 0.0244813 |
| EXOC4 | exocyst complex component 4 | 0.0242885 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0242371 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0242367 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0240506 |
| CNTN4 | contactin 4 | 0.0235395 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0235107 |
| AMOTL1 | angiomotin like 1 | 0.023498 |
| STC1 | stanniocalcin 1 | 0.0233747 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.258074 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209174 |
| IGF2 | insulin-like growth factor 2 | -0.142534 |
| RPS6 | ribosomal protein S6 | -0.090095 |
| ACTG1 | actin gamma 1 | -0.0819621 |
| VIM | vimentin | -0.0735176 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0679875 |
| RPL19 | ribosomal protein L19 | -0.0648987 |
| COL1A1 | collagen, type I, alpha 1 | -0.0596835 |
| PTMA | prothymosin, alpha | -0.058511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.058036 |
| RPS25 | ribosomal protein S25 | -0.0569904 |
| LMNA | lamin A/C | -0.0546755 |
| RPL34 | ribosomal protein L34 | -0.0525979 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0516088 |
| RPL35A | ribosomal protein L35a | -0.0510421 |
| WDR45B | WD repeat domain 45B | -0.0501955 |
| PCDH9 | protocadherin 9 | -0.050183 |
| B2M | beta-2-microglobulin | -0.046909 |
| S100A6 | S100 calcium binding protein A6 | -0.0460903 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0432169 |
| RPS23 | ribosomal protein S23 | -0.042429 |
| HMGB2 | high mobility group box 2 | -0.0409313 |
| PHIP | pleckstrin homology domain interacting protein | -0.0407682 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402411 |
| RUNX1 | runt-related transcription factor 1 | -0.0400694 |
| TMSB10 | thymosin beta 10 | -0.0397907 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0396665 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0383291 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.038093 |
| ANXA2 | annexin A2 | -0.0378413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0373505 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0363036 |
| RPS16 | ribosomal protein S16 | -0.0350846 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0343154 |
| GDF15 | growth differentiation factor 15 | -0.0340089 |
| PTGES2 | prostaglandin E synthase 2 | -0.0339136 |
| FTL | ferritin, light polypeptide | -0.032876 |
| RPL38 | ribosomal protein L38 | -0.0328694 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0328577 |
| RTN4 | reticulon 4 | -0.032268 |
| RPS8 | ribosomal protein S8 | -0.0322085 |
| TLK2 | tousled-like kinase 2 | -0.0317684 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0314032 |
| RPS24 | ribosomal protein S24 | -0.0313591 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0313307 |
| CCND1 | cyclin D1 | -0.0312342 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0312031 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0304983 |
| S100A10 | S100 calcium binding protein A10 | -0.0298233 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0297656 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0296927 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0295235 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.029175 |
| RPL28 | ribosomal protein L28 | -0.0291583 |
| TOB1 | transducer of ERBB2, 1 | -0.0291099 |
| QKI | QKI, KH domain containing, RNA binding | -0.0288679 |
| MTDH | metadherin | -0.0287543 |
| RPL26 | ribosomal protein L26 | -0.0284726 |
| CLINT1 | clathrin interactor 1 | -0.0282535 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0282383 |
| EFNA5 | ephrin-A5 | -0.0281737 |
| RPS15 | ribosomal protein S15 | -0.0280974 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0278469 |
| GOLGA4 | golgin A4 | -0.0278414 |
| SPAG9 | sperm associated antigen 9 | -0.0278195 |
| HMGA1 | high mobility group AT-hook 1 | -0.0274727 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0272824 |
| HBS1L | HBS1-like translational GTPase | -0.0271676 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0266049 |
| RPL11 | ribosomal protein L11 | -0.0264664 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0263605 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0259889 |
| RPL36 | ribosomal protein L36 | -0.0259686 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0257763 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0257632 |
| OGA | O-GlcNAcase | -0.0254704 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0254525 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0253725 |
| RNF145 | ring finger protein 145 | -0.025251 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0252504 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0252226 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0251021 |
| RPS13 | ribosomal protein S13 | -0.0250155 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0249964 |
| RALYL | RALY RNA binding protein-like | -0.0249944 |
| KLHL24 | kelch-like family member 24 | -0.0248279 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0246945 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0246756 |
| AFTPH | aftiphilin | -0.0246359 |
| HDAC2 | histone deacetylase 2 | -0.0245433 |
| RPS21 | ribosomal protein S21 | -0.0243918 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0243683 |
| CBFB | core-binding factor, beta subunit | -0.0243338 |
| FUS | FUS RNA binding protein | -0.024253 |
| RPS20 | ribosomal protein S20 | -0.024192 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0240443 |
| RACK1 | receptor for activated C kinase 1 | -0.0240386 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0239517 |
| HLA-A | major histocompatibility complex, class I, A | -0.0239194 |
