| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.0993815 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0850979 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0713407 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0691225 |
| NAV1 | neuron navigator 1 | 0.0687485 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0600857 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0598251 |
| PTMA | prothymosin, alpha | 0.0571348 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0560533 |
| RCOR1 | REST corepressor 1 | 0.05437 |
| MYO10 | myosin X | 0.0524227 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0519903 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0516622 |
| MSN | moesin | 0.050093 |
| TMSB10 | thymosin beta 10 | 0.0485676 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0484535 |
| COL6A3 | collagen, type VI, alpha 3 | 0.045467 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0447919 |
| CLIC4 | chloride intracellular channel 4 | 0.0441024 |
| RRM2 | ribonucleotide reductase M2 | 0.0434324 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.043057 |
| VCL | vinculin | 0.0421995 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0414883 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0414558 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0408907 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0408196 |
| COL5A1 | collagen, type V, alpha 1 | 0.0398898 |
| INTS6 | integrator complex subunit 6 | 0.0396109 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0391974 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.038637 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0385514 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0384375 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0383407 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038114 |
| POTEF | POTE ankyrin domain family, member F | 0.0381053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0377838 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0377032 |
| ACTG1 | actin gamma 1 | 0.0376425 |
| WWOX | WW domain containing oxidoreductase | 0.0376037 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0375154 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0371913 |
| IER3 | immediate early response 3 | 0.0366778 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0365119 |
| RPS6 | ribosomal protein S6 | 0.0352684 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0348621 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0348061 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0339244 |
| DST | dystonin | 0.0337969 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0335666 |
| FBXO11 | F-box protein 11 | 0.0324718 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0321513 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.031905 |
| ACTN1 | actinin, alpha 1 | 0.0314603 |
| INHBA | inhibin, beta A | 0.0310181 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0308993 |
| IL11 | interleukin 11 | 0.0308197 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.029874 |
| MLPH | melanophilin | 0.02928 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0287886 |
| CD44 | CD44 molecule (Indian blood group) | 0.0286543 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0286317 |
| HOMER1 | homer scaffolding protein 1 | 0.0286195 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0284967 |
| CAPRIN2 | caprin family member 2 | 0.0284185 |
| PDE8A | phosphodiesterase 8A | 0.0277278 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0276409 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0268859 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0268606 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0266344 |
| PRKCA | protein kinase C, alpha | 0.0264887 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0264525 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0258224 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255618 |
| S100A10 | S100 calcium binding protein A10 | 0.0255039 |
| SETX | senataxin | 0.025465 |
| CEP128 | centrosomal protein 128kDa | 0.0251005 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0249115 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0247511 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0243921 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243181 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0243128 |
| PALLD | palladin, cytoskeletal associated protein | 0.0242176 |
| SSH2 | slingshot protein phosphatase 2 | 0.0241973 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0241666 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.024166 |
| JUN | jun proto-oncogene | 0.0240123 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0238716 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0237807 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0235094 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0234435 |
| STC1 | stanniocalcin 1 | 0.0232826 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.023263 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0232573 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0230372 |
| SEPTIN9 | septin 9 | 0.0230354 |
| GRAMD1B | GRAM domain containing 1B | 0.0229113 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0225687 |
| TOP1 | topoisomerase (DNA) I | 0.0222281 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0221616 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0221423 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.258627 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.19343 |
| FN1 | fibronectin 1 | -0.181686 |
| CDH13 | cadherin 13 | -0.112172 |
| NDRG1 | N-myc downstream regulated 1 | -0.0993576 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0958729 |
| TENM2 | teneurin transmembrane protein 2 | -0.0898802 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0819649 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0755235 |
| LOX | lysyl oxidase | -0.0727694 |
| SBF2 | SET binding factor 2 | -0.0719119 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0637664 |
| AHNAK | AHNAK nucleoprotein | -0.0616574 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0598021 |
| GOLGA4 | golgin A4 | -0.0593977 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0565827 |
| CD109 | CD109 molecule | -0.055827 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0545252 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.053769 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0535753 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0527199 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0514989 |
| NGLY1 | N-glycanase 1 | -0.0514572 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0510627 |
| PDE10A | phosphodiesterase 10A | -0.0478111 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0466046 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0461725 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0451648 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0436769 |
| FMN1 | formin 1 | -0.0430723 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0409955 |
| CDCP1 | CUB domain containing protein 1 | -0.0406059 |
| OSMR | oncostatin M receptor | -0.0405349 |
| ZNF292 | zinc finger protein 292 | -0.0397686 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0394769 |
| YEATS2 | YEATS domain containing 2 | -0.0387122 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0387011 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.038645 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0380375 |
| HMGA2 | high mobility group AT-hook 2 | -0.0379754 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.037598 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0362947 |
| CCND1 | cyclin D1 | -0.0356175 |
| RRBP1 | ribosome binding protein 1 | -0.0353946 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0350621 |
| LDHA | lactate dehydrogenase A | -0.0348944 |
| RUNX1 | runt-related transcription factor 1 | -0.0347658 |
| CCDC91 | coiled-coil domain containing 91 | -0.0338062 |
| TNNC1 | troponin C type 1 (slow) | -0.033516 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0330662 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328419 |
| EFNA5 | ephrin-A5 | -0.0323847 |
| CANX | calnexin | -0.0318209 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0313166 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.031185 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0294947 |
| CLTC | clathrin, heavy chain (Hc) | -0.0287425 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0285934 |
| LAMB3 | laminin, beta 3 | -0.0279617 |
| SFXN1 | sideroflexin 1 | -0.0267681 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0264752 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0258131 |
| RASA3 | RAS p21 protein activator 3 | -0.0257524 |
| MMP12 | matrix metallopeptidase 12 | -0.0257259 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0256794 |
| FLNB | filamin B, beta | -0.0253536 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0252287 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.02507 |
| DUSP6 | dual specificity phosphatase 6 | -0.0250288 |
| SPAG9 | sperm associated antigen 9 | -0.0249445 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0248092 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0245987 |
| ETNK1 | ethanolamine kinase 1 | -0.0244515 |
| OGA | O-GlcNAcase | -0.0242281 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0241499 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.024114 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0238569 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0238345 |
| TUBB6 | tubulin, beta 6 class V | -0.0236736 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0235496 |
| NUP214 | nucleoporin 214kDa | -0.0233882 |
| CALD1 | caldesmon 1 | -0.0233088 |
| PKM | pyruvate kinase, muscle | -0.0227805 |
| CDK19 | cyclin-dependent kinase 19 | -0.0225246 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0224054 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0223507 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0223003 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0222923 |
| WDR45B | WD repeat domain 45B | -0.022285 |
| SGO2 | shugoshin 2 | -0.0221661 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0218344 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0216002 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0214993 |
| ARRDC3 | arrestin domain containing 3 | -0.0214975 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0214228 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0209031 |
| FSTL1 | follistatin-like 1 | -0.0208999 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0208384 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0208312 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0207996 |
