| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.114789 |
| LMO7 | LIM domain 7 | 0.109933 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0962359 |
| CTBP2 | C-terminal binding protein 2 | 0.0721917 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0642612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0584464 |
| INTS6 | integrator complex subunit 6 | 0.0529897 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0515964 |
| TJP1 | tight junction protein 1 | 0.050122 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0500298 |
| NTN4 | netrin 4 | 0.048958 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0478809 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0473674 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0461025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0452914 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0447051 |
| UTRN | utrophin | 0.0439879 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0438431 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0423548 |
| PRR5L | proline rich 5 like | 0.042203 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0370424 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0369775 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0364035 |
| CCNYL1 | cyclin Y-like 1 | 0.0360294 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0352578 |
| PLK2 | polo-like kinase 2 | 0.0349593 |
| VCL | vinculin | 0.0341932 |
| ATXN1 | ataxin 1 | 0.0340883 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0337555 |
| FAT1 | FAT atypical cadherin 1 | 0.0337078 |
| KRT20 | keratin 20, type I | 0.032637 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0309141 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0298065 |
| VMP1 | vacuole membrane protein 1 | 0.0265401 |
| POF1B | premature ovarian failure, 1B | 0.0261237 |
| DST | dystonin | 0.0260171 |
| PDZD8 | PDZ domain containing 8 | 0.0253496 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0253245 |
| STK24 | serine/threonine kinase 24 | 0.0251674 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.025078 |
| MYEOV | myeloma overexpressed | 0.0244961 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0240532 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0239259 |
| EGFR | epidermal growth factor receptor | 0.0235284 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0235082 |
| SGMS2 | sphingomyelin synthase 2 | 0.0229822 |
| EPS8L1 | EPS8-like 1 | 0.0228619 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0227619 |
| BCL2L1 | BCL2-like 1 | 0.0226044 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.022573 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0221427 |
| WLS | wntless Wnt ligand secretion mediator | 0.0219329 |
| DUSP16 | dual specificity phosphatase 16 | 0.0218473 |
| FHL2 | four and a half LIM domains 2 | 0.0212043 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.02065 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.020334 |
| POTEF | POTE ankyrin domain family, member F | 0.0200896 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.019903 |
| PDE10A | phosphodiesterase 10A | 0.0198555 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0194243 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0187799 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0187786 |
| KLF12 | Kruppel-like factor 12 | 0.0187421 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0186888 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0183509 |
| ATXN7L1 | ataxin 7-like 1 | 0.018349 |
| ANXA11 | annexin A11 | 0.0183377 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180809 |
| TUFT1 | tuftelin 1 | 0.0178199 |
| PPL | periplakin | 0.0173729 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0171558 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0171467 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0170133 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0169233 |
| HOMER1 | homer scaffolding protein 1 | 0.0168751 |
| ETV6 | ets variant 6 | 0.0168185 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0164119 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0163935 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0163808 |
| MYO1E | myosin IE | 0.0163597 |
| MYOF | myoferlin | 0.0161666 |
| MYO10 | myosin X | 0.0160351 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0158796 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0157625 |
| AREG | amphiregulin | 0.0153717 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0152411 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0151391 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0151004 |
| TLE4 | transducin-like enhancer of split 4 | 0.0150568 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0150292 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0149826 |
| NEBL | nebulette | 0.014755 |
| ACVR1 | activin A receptor, type I | 0.0146817 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0146178 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0145805 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0144409 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0142283 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0141749 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0136573 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0135774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.14033 |
| PTMA | prothymosin, alpha | -0.12899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121838 |
| FTL | ferritin, light polypeptide | -0.0822249 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0795893 |
| RPLP1 | ribosomal protein, large, P1 | -0.0732455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0728201 |
| RPS6 | ribosomal protein S6 | -0.0723067 |
| NDRG1 | N-myc downstream regulated 1 | -0.0667334 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0649062 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0613242 |
| GOLGA4 | golgin A4 | -0.0565022 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0525654 |
| TMSB10 | thymosin beta 10 | -0.0517626 |
| RPS24 | ribosomal protein S24 | -0.0508694 |
| RPS19 | ribosomal protein S19 | -0.0477417 |
| RPL34 | ribosomal protein L34 | -0.0476526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0473231 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0472337 |
| RPS3 | ribosomal protein S3 | -0.0450633 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0445562 |
| S100A6 | S100 calcium binding protein A6 | -0.0442618 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0436922 |
| PTK2 | protein tyrosine kinase 2 | -0.043643 |
| B2M | beta-2-microglobulin | -0.0424735 |
| RPL35A | ribosomal protein L35a | -0.0418242 |
| RPS8 | ribosomal protein S8 | -0.0415933 |
| RPL12 | ribosomal protein L12 | -0.040268 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0402135 |
| ZNF292 | zinc finger protein 292 | -0.0398317 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0381832 |
| CANX | calnexin | -0.0380583 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380517 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.037529 |
| AHNAK | AHNAK nucleoprotein | -0.0369082 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0363711 |
| RPLP0 | ribosomal protein, large, P0 | -0.0361463 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0359835 |
| RPLP2 | ribosomal protein, large, P2 | -0.0357349 |
| RPL27A | ribosomal protein L27a | -0.0355493 |
| TXNRD1 | thioredoxin reductase 1 | -0.0347487 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0345809 |
| MKI67 | marker of proliferation Ki-67 | -0.0345713 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0336926 |
| RPL23 | ribosomal protein L23 | -0.033553 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0334176 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.032777 |
| LYZ | lysozyme | -0.0326828 |
| RPL26 | ribosomal protein L26 | -0.0324058 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0323215 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0322335 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0321881 |
| MORF4L2 | mortality factor 4 like 2 | -0.0321395 |
| ACTG1 | actin gamma 1 | -0.0317286 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0316015 |
| RPS13 | ribosomal protein S13 | -0.0315838 |
| RPS16 | ribosomal protein S16 | -0.031216 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0307637 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0306412 |
| JUN | jun proto-oncogene | -0.0306001 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0305113 |
| RPS12 | ribosomal protein S12 | -0.0301896 |
| RPS21 | ribosomal protein S21 | -0.0299645 |
| ANXA2 | annexin A2 | -0.0298526 |
| EPCAM | epithelial cell adhesion molecule | -0.0297511 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0297348 |
| RPL13A | ribosomal protein L13a | -0.0291721 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0290262 |
| DIAPH2 | diaphanous-related formin 2 | -0.0288935 |
| SBF2 | SET binding factor 2 | -0.0288025 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0278086 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0272749 |
| RRBP1 | ribosome binding protein 1 | -0.0272036 |
| LDHA | lactate dehydrogenase A | -0.0272018 |
| GNAS | GNAS complex locus | -0.0268623 |
| PGK1 | phosphoglycerate kinase 1 | -0.0267319 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0266896 |
| JMJD1C | jumonji domain containing 1C | -0.0266135 |
| RPS27A | ribosomal protein S27a | -0.0265989 |
| NF1 | neurofibromin 1 | -0.0264758 |
| RPL11 | ribosomal protein L11 | -0.0263978 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0262686 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026261 |
| FBXO32 | F-box protein 32 | -0.0262379 |
| KIF5B | kinesin family member 5B | -0.0261008 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0259952 |
| HDLBP | high density lipoprotein binding protein | -0.0257858 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0254202 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0254188 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0254046 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0252706 |
| RPL4 | ribosomal protein L4 | -0.0251782 |
| RPL37 | ribosomal protein L37 | -0.0249947 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0249826 |
| CALU | calumenin | -0.0249069 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0248457 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0240443 |
| ENO1 | enolase 1, (alpha) | -0.0239952 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0237584 |
| LMNA | lamin A/C | -0.0236591 |
