| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.238691 |
| LMO7 | LIM domain 7 | 0.144768 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.103863 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0956041 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0820723 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0723367 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0720844 |
| ASPH | aspartate beta-hydroxylase | 0.0720572 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0702518 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0669027 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0667716 |
| RIGI | RNA sensor RIG-I | 0.0661966 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0638946 |
| MYOF | myoferlin | 0.0621886 |
| VCL | vinculin | 0.0589637 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0581124 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0539723 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0523088 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0517326 |
| AOPEP | aminopeptidase O (putative) | 0.0516799 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0505016 |
| PLS3 | plastin 3 | 0.0498419 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0484954 |
| HMGA2 | high mobility group AT-hook 2 | 0.0477438 |
| AHNAK | AHNAK nucleoprotein | 0.0451777 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.043563 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.043331 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0422864 |
| AMOTL1 | angiomotin like 1 | 0.0411535 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0410818 |
| LAMC2 | laminin, gamma 2 | 0.0408391 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0404505 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0397883 |
| MTSS1 | metastasis suppressor 1 | 0.0392793 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0390962 |
| SULF2 | sulfatase 2 | 0.0386969 |
| DST | dystonin | 0.0381084 |
| IFI44L | interferon-induced protein 44-like | 0.0367062 |
| INTS6 | integrator complex subunit 6 | 0.0366389 |
| RASAL2 | RAS protein activator like 2 | 0.0365726 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359993 |
| SMAD3 | SMAD family member 3 | 0.035365 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0350331 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0348645 |
| EFNA5 | ephrin-A5 | 0.0347139 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0335845 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0335591 |
| FOXO1 | forkhead box O1 | 0.032686 |
| PALLD | palladin, cytoskeletal associated protein | 0.0326167 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0322828 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0321626 |
| PRELID2 | PRELI domain containing 2 | 0.0320186 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0310205 |
| PTK2 | protein tyrosine kinase 2 | 0.030976 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0309344 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0302564 |
| KIAA1671 | KIAA1671 | 0.029865 |
| MTAP | methylthioadenosine phosphorylase | 0.029802 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0296876 |
| FOXP1 | forkhead box P1 | 0.0296348 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0294037 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0292296 |
| RNF217 | ring finger protein 217 | 0.0290532 |
| MECOM | MDS1 and EVI1 complex locus | 0.0288159 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0286134 |
| SIK3 | SIK family kinase 3 | 0.0285605 |
| CTBP2 | C-terminal binding protein 2 | 0.0284523 |
| SP100 | SP100 nuclear antigen | 0.0282427 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0279856 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0279362 |
| NEK7 | NIMA-related kinase 7 | 0.0274836 |
| CDK6 | cyclin-dependent kinase 6 | 0.0271202 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0264495 |
| FRMD6 | FERM domain containing 6 | 0.0262357 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0258645 |
| IFI44 | interferon-induced protein 44 | 0.0258338 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0256862 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0252272 |
| LUZP1 | leucine zipper protein 1 | 0.0247407 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0246982 |
| MSN | moesin | 0.0246603 |
| RAD51B | RAD51 paralog B | 0.0245886 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0239661 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0239423 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0238175 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0237199 |
| CD44 | CD44 molecule (Indian blood group) | 0.0236155 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0235789 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0235022 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.023333 |
| PLEC | plectin | 0.0231855 |
| PRSS23 | protease, serine, 23 | 0.0230437 |
| PLXNA2 | plexin A2 | 0.0229888 |
| HDAC9 | histone deacetylase 9 | 0.0228524 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0225793 |
| AGO2 | argonaute RISC catalytic component 2 | 0.022579 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0225483 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0223245 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0221656 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0219975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147003 |
| NDRG1 | N-myc downstream regulated 1 | -0.133674 |
| FLNB | filamin B, beta | -0.095879 |
| CLU | clusterin | -0.0928048 |
| TMSB10 | thymosin beta 10 | -0.0835369 |
| MT2A | metallothionein 2A | -0.0782547 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0589385 |
| RPS6 | ribosomal protein S6 | -0.0525719 |
| GOLGA4 | golgin A4 | -0.0524977 |
| PTMA | prothymosin, alpha | -0.0508156 |
| EMP1 | epithelial membrane protein 1 | -0.0503945 |
| IGF2 | insulin-like growth factor 2 | -0.045822 |
| S100A10 | S100 calcium binding protein A10 | -0.0455784 |
| RPS13 | ribosomal protein S13 | -0.0440541 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.043966 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437296 |
| GNAS | GNAS complex locus | -0.0430917 |
| RPS21 | ribosomal protein S21 | -0.043033 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420157 |
| B2M | beta-2-microglobulin | -0.0417049 |
| WASF2 | WAS protein family, member 2 | -0.0415327 |
| HM13 | histocompatibility (minor) 13 | -0.0414194 |
| EFHD2 | EF-hand domain family, member D2 | -0.0402943 |
| RPLP2 | ribosomal protein, large, P2 | -0.0389994 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0385895 |
| HLA-B | major histocompatibility complex, class I, B | -0.0376904 |
| RPS19 | ribosomal protein S19 | -0.037104 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0370132 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0359407 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0350208 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338983 |
| SQLE | squalene epoxidase | -0.0336347 |
| S100A2 | S100 calcium binding protein A2 | -0.0327039 |
| LMNA | lamin A/C | -0.0325025 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0322134 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0318878 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0316985 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0315902 |
| RPL8 | ribosomal protein L8 | -0.0314476 |
| S100A6 | S100 calcium binding protein A6 | -0.0310413 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310104 |
| MORF4L2 | mortality factor 4 like 2 | -0.0309392 |
| DSTN | destrin (actin depolymerizing factor) | -0.0303256 |
| SRP54 | signal recognition particle 54kDa | -0.0299969 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0289462 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0288369 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0285967 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0284901 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0281521 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280536 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0278332 |
| PKM | pyruvate kinase, muscle | -0.027702 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0276137 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0274275 |
| CD99 | CD99 molecule | -0.0273236 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0271907 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.027035 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264865 |
| RPLP1 | ribosomal protein, large, P1 | -0.02623 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0259483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0258657 |
| HLA-A | major histocompatibility complex, class I, A | -0.0254293 |
| MYADM | myeloid-associated differentiation marker | -0.0254112 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0251762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0249616 |
| ARF4 | ADP-ribosylation factor 4 | -0.0246986 |
| RPL7A | ribosomal protein L7a | -0.024623 |
| COG5 | component of oligomeric golgi complex 5 | -0.0239238 |
| RPS8 | ribosomal protein S8 | -0.0237759 |
| RPS23 | ribosomal protein S23 | -0.0236095 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0231705 |
| CSNK1E | casein kinase 1, epsilon | -0.0231227 |
| FTL | ferritin, light polypeptide | -0.0229494 |
| RPL32 | ribosomal protein L32 | -0.0229408 |
| RPL34 | ribosomal protein L34 | -0.0226849 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0224876 |
| RPS25 | ribosomal protein S25 | -0.0223913 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0223703 |
| NUCB2 | nucleobindin 2 | -0.0223131 |
| RPL35A | ribosomal protein L35a | -0.022278 |
| RPL23 | ribosomal protein L23 | -0.0221915 |
| PFN1 | profilin 1 | -0.0221719 |
| ANXA1 | annexin A1 | -0.0219557 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0218956 |
| FOSL1 | FOS-like antigen 1 | -0.0217286 |
| TMSB4X | thymosin beta 4, X-linked | -0.0216102 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0215174 |
| MT1X | metallothionein 1X | -0.0215071 |
| LOC112694756 | uncharaterized LOC112694756 | -0.021432 |
| EPHA2 | EPH receptor A2 | -0.0212154 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0211632 |
| GOLGA2 | golgin A2 | -0.0211524 |
| YBX3 | Y box binding protein 3 | -0.0209236 |
| LMAN1 | lectin, mannose-binding, 1 | -0.020862 |
| KRT17 | keratin 17, type I | -0.0206562 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0206534 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0204836 |
| RPL12 | ribosomal protein L12 | -0.0204562 |
| TMEM165 | transmembrane protein 165 | -0.0204495 |
| S100A9 | S100 calcium binding protein A9 | -0.0203903 |
