| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.112268 |
| POTEF | POTE ankyrin domain family, member F | 0.0958076 |
| RPS12 | ribosomal protein S12 | 0.0626048 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0441051 |
| PCBP2 | poly(rC) binding protein 2 | 0.0436986 |
| MYO1E | myosin IE | 0.0391818 |
| RPL3 | ribosomal protein L3 | 0.0336075 |
| PRELID2 | PRELI domain containing 2 | 0.0328375 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321494 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0292069 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.028858 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0288067 |
| ASPH | aspartate beta-hydroxylase | 0.0279465 |
| LDHA | lactate dehydrogenase A | 0.0272832 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0269618 |
| MYOF | myoferlin | 0.026569 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0256103 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0251912 |
| ENO1 | enolase 1, (alpha) | 0.0249805 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0238503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0237787 |
| MT2A | metallothionein 2A | 0.0237641 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0235887 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229219 |
| MLEC | malectin | 0.0228823 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0224294 |
| CLDN4 | claudin 4 | 0.0223919 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0221007 |
| CCNYL1 | cyclin Y-like 1 | 0.0219642 |
| TRIM2 | tripartite motif containing 2 | 0.0218745 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0215533 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0213225 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0209996 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0209991 |
| INTS6 | integrator complex subunit 6 | 0.020475 |
| AREG | amphiregulin | 0.0203397 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0196635 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0196571 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0192602 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0189854 |
| SFPQ | splicing factor proline/glutamine-rich | 0.018858 |
| PGK1 | phosphoglycerate kinase 1 | 0.0183855 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0179619 |
| RPL23 | ribosomal protein L23 | 0.0179058 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0178984 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0177561 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0174861 |
| RPS3 | ribosomal protein S3 | 0.0174279 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0173212 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0170055 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0167959 |
| CENPF | centromere protein F, 350/400kDa | 0.0166076 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | 0.0165221 |
| RPL21 | ribosomal protein L21 | 0.0163947 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0161785 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0160656 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0155569 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0154341 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0152816 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0149973 |
| RNF145 | ring finger protein 145 | 0.0149353 |
| AUTS2 | autism susceptibility candidate 2 | 0.0146098 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.014492 |
| DUSP4 | dual specificity phosphatase 4 | 0.0143705 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0141996 |
| NRDC | nardilysin convertase | 0.0141971 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0139475 |
| RACK1 | receptor for activated C kinase 1 | 0.0136895 |
| RPS18 | ribosomal protein S18 | 0.0135033 |
| MCL1 | myeloid cell leukemia 1 | 0.0134259 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0133483 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.013284 |
| KIZ | kizuna centrosomal protein | 0.0132359 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0132059 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0131253 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0129418 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0128845 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0128034 |
| PTEN | phosphatase and tensin homolog | 0.0126634 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0126234 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0124273 |
| TPI1 | triosephosphate isomerase 1 | 0.0122753 |
| LIMA1 | LIM domain and actin binding 1 | 0.0122424 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0121537 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0119957 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0119764 |
| MEF2C | myocyte enhancer factor 2C | 0.011958 |
| CPNE1 | copine I | 0.0118737 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0118633 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0118106 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0116858 |
| ANO6 | anoctamin 6 | 0.0114074 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0112574 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0111685 |
| MUC13 | mucin 13, cell surface associated | 0.0110718 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0110657 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0110059 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0109454 |
| GPHN | gephyrin | 0.0107792 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0106376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.166984 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126195 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.122776 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.093396 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0927867 |
| RPLP1 | ribosomal protein, large, P1 | -0.0910269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.089721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0780634 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0746148 |
| RPL34 | ribosomal protein L34 | -0.0743431 |
| ANXA2 | annexin A2 | -0.0715052 |
| FLNB | filamin B, beta | -0.0706836 |
| LMO7 | LIM domain 7 | -0.0682173 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0655959 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0641778 |
| RRBP1 | ribosome binding protein 1 | -0.0631332 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0596838 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0594751 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0556432 |
| RPS6 | ribosomal protein S6 | -0.0549472 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0543623 |
| CANX | calnexin | -0.0538831 |
| DSPP | dentin sialophosphoprotein | -0.0520126 |
| FRMD5 | FERM domain containing 5 | -0.0503312 |
| COG5 | component of oligomeric golgi complex 5 | -0.0491775 |
| RPL4 | ribosomal protein L4 | -0.0489319 |
| AHNAK | AHNAK nucleoprotein | -0.0468554 |
| RPS24 | ribosomal protein S24 | -0.0467664 |
| AOPEP | aminopeptidase O (putative) | -0.0448738 |
| PTMA | prothymosin, alpha | -0.0435796 |
| SVIL | supervillin | -0.043273 |
| NPSR1 | neuropeptide S receptor 1 | -0.0430476 |
| MSI2 | musashi RNA-binding protein 2 | -0.0425854 |
| JMJD1C | jumonji domain containing 1C | -0.0424565 |
| COBL | cordon-bleu WH2 repeat protein | -0.0424188 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0423164 |
| GOLGA4 | golgin A4 | -0.0418945 |
| DSG2 | desmoglein 2 | -0.0413685 |
| CUX1 | cut-like homeobox 1 | -0.0407493 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0406225 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0403963 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0395377 |
| RREB1 | ras responsive element binding protein 1 | -0.0390965 |
| ACTN4 | actinin, alpha 4 | -0.0388624 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0387967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0385002 |
| LAMB3 | laminin, beta 3 | -0.0384635 |
| CALU | calumenin | -0.0384364 |
| RPL38 | ribosomal protein L38 | -0.0382007 |
| MCU | mitochondrial calcium uniporter | -0.0372373 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0364208 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0360469 |
| DENND1A | DENN/MADD domain containing 1A | -0.0358829 |
| TJP1 | tight junction protein 1 | -0.0350133 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0347506 |
| XAF1 | XIAP associated factor 1 | -0.0339161 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0338822 |
| RPS21 | ribosomal protein S21 | -0.0338399 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0337855 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0332958 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0332799 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0330354 |
| WWC1 | WW and C2 domain containing 1 | -0.0330194 |
| PERP | PERP, TP53 apoptosis effector | -0.0329 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0327177 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0323504 |
| RPL26 | ribosomal protein L26 | -0.0316808 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0314106 |
| FERMT1 | fermitin family member 1 | -0.03136 |
| DSG3 | desmoglein 3 | -0.0308667 |
| FUS | FUS RNA binding protein | -0.0307762 |
| TSPAN8 | tetraspanin 8 | -0.0305278 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0304844 |
| EZR | ezrin | -0.0304132 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0301286 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0300499 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0300035 |
| CCND1 | cyclin D1 | -0.0298871 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0298105 |
| PRSS3 | protease, serine, 3 | -0.0297617 |
| RPL35A | ribosomal protein L35a | -0.0296251 |
| RPS27A | ribosomal protein S27a | -0.029614 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0295748 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0294309 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0290883 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0288458 |
| RPS8 | ribosomal protein S8 | -0.0287314 |
| TCF12 | transcription factor 12 | -0.0286733 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.028554 |
| FOXO1 | forkhead box O1 | -0.0285413 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.028454 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0284399 |
| EPCAM | epithelial cell adhesion molecule | -0.0280657 |
| FOXO3 | forkhead box O3 | -0.0279672 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0279218 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0269819 |
| RPS29 | ribosomal protein S29 | -0.0267615 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0267398 |
| FER | fer (fps/fes related) tyrosine kinase | -0.026674 |
| RPL37A | ribosomal protein L37a | -0.0264416 |
