| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.199061 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0969736 |
| TXNIP | thioredoxin interacting protein | 0.0820596 |
| PTMA | prothymosin, alpha | 0.0801238 |
| FMNL2 | formin-like 2 | 0.079698 |
| PRELID2 | PRELI domain containing 2 | 0.076983 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0581424 |
| TP63 | tumor protein p63 | 0.0580595 |
| MYOF | myoferlin | 0.0569451 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0563827 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0540679 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0531739 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0527131 |
| CADM2 | cell adhesion molecule 2 | 0.0496625 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0489994 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.047575 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0472472 |
| VCL | vinculin | 0.0471952 |
| OGA | O-GlcNAcase | 0.0469587 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0465514 |
| RPS12 | ribosomal protein S12 | 0.0464422 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0462266 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0456088 |
| CAPRIN2 | caprin family member 2 | 0.0441681 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0440272 |
| SQSTM1 | sequestosome 1 | 0.0394977 |
| HLA-B | major histocompatibility complex, class I, B | 0.039349 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0391886 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0385639 |
| PLIN2 | perilipin 2 | 0.0378484 |
| DNER | delta/notch-like EGF repeat containing | 0.0374121 |
| POTEF | POTE ankyrin domain family, member F | 0.0372164 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0366209 |
| EREG | epiregulin | 0.0360531 |
| EZR | ezrin | 0.0352445 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0351244 |
| B2M | beta-2-microglobulin | 0.0340685 |
| EPHA4 | EPH receptor A4 | 0.0326336 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0318059 |
| SDC4 | syndecan 4 | 0.0316943 |
| KLF6 | Kruppel-like factor 6 | 0.0316266 |
| EFNA5 | ephrin-A5 | 0.0312962 |
| RNF213 | ring finger protein 213 | 0.0306855 |
| ADM | adrenomedullin | 0.0305016 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0304028 |
| CD44 | CD44 molecule (Indian blood group) | 0.0302794 |
| SLK | STE20-like kinase | 0.030224 |
| RAD51B | RAD51 paralog B | 0.0301462 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.02987 |
| SP100 | SP100 nuclear antigen | 0.0293838 |
| DPYD | dihydropyrimidine dehydrogenase | 0.029044 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0287281 |
| CALR | calreticulin | 0.0283723 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0280002 |
| SMYD3 | SET and MYND domain containing 3 | 0.0278572 |
| UBE4B | ubiquitination factor E4B | 0.027708 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0272144 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269678 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0265875 |
| SPAG9 | sperm associated antigen 9 | 0.026537 |
| HDAC9 | histone deacetylase 9 | 0.0264675 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0261334 |
| PDE8A | phosphodiesterase 8A | 0.0261088 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0260712 |
| TRIM56 | tripartite motif containing 56 | 0.0260352 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0259959 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0258635 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0258138 |
| SYAP1 | synapse associated protein 1 | 0.025654 |
| CEP250 | centrosomal protein 250kDa | 0.0255081 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0251491 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0250554 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.02499 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0249416 |
| ASPH | aspartate beta-hydroxylase | 0.0249294 |
| VMP1 | vacuole membrane protein 1 | 0.0247876 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0240348 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0238512 |
| TNS3 | tensin 3 | 0.0233793 |
| MT2A | metallothionein 2A | 0.0233524 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0233053 |
| COL5A2 | collagen, type V, alpha 2 | 0.0226718 |
| MT1E | metallothionein 1E | 0.0226552 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0222058 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0220345 |
| SSH2 | slingshot protein phosphatase 2 | 0.0218916 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0218762 |
| FHIT | fragile histidine triad | 0.0216791 |
| FTL | ferritin, light polypeptide | 0.0216683 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0216357 |
| INTS6 | integrator complex subunit 6 | 0.0215647 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0215428 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0214661 |
| RPL12 | ribosomal protein L12 | 0.0214628 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0214498 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0214384 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0212921 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212783 |
| GOLGB1 | golgin B1 | 0.0210106 |
| ZNF638 | zinc finger protein 638 | 0.0209481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.396032 |
| TXNRD1 | thioredoxin reductase 1 | -0.213004 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.137712 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.109383 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0919804 |
| EGR1 | early growth response 1 | -0.0899345 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0810688 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0723771 |
| RAI1 | retinoic acid induced 1 | -0.0717994 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0693609 |
| HMGA1 | high mobility group AT-hook 1 | -0.0684174 |
| ACTG1 | actin gamma 1 | -0.0676666 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0643828 |
| LOC112694756 | uncharaterized LOC112694756 | -0.064241 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0622245 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0589827 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0585787 |
| CENPF | centromere protein F, 350/400kDa | -0.0581801 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.05555 |
| VIM | vimentin | -0.0523205 |
| TMEM41B | transmembrane protein 41B | -0.0511951 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.050938 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.050744 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0478604 |
| RTN4 | reticulon 4 | -0.0466624 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.040114 |
| APP | amyloid beta (A4) precursor protein | -0.0389426 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0386835 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0381381 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0374575 |
| SRGN | serglycin | -0.0373881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0369381 |
| AHNAK | AHNAK nucleoprotein | -0.034318 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0342645 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0342105 |
| PYGB | phosphorylase, glycogen; brain | -0.034194 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0338068 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0337328 |
| WDR43 | WD repeat domain 43 | -0.0333032 |
| TMSB10 | thymosin beta 10 | -0.0328725 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0322928 |
| UPP1 | uridine phosphorylase 1 | -0.0320818 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0314322 |
| ANKRD11 | ankyrin repeat domain 11 | -0.03141 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0310984 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0310861 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0307599 |
| MKI67 | marker of proliferation Ki-67 | -0.0306121 |
| TAPBP | TAP binding protein (tapasin) | -0.0305589 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0305287 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0303011 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0294355 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0291189 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0291073 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0288363 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0284013 |
| OSMR | oncostatin M receptor | -0.0282468 |
| OLA1 | Obg-like ATPase 1 | -0.0282224 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280391 |
| USP34 | ubiquitin specific peptidase 34 | -0.0270977 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0267759 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.026565 |
| PRRC2C | proline-rich coiled-coil 2C | -0.026548 |
| RASAL2 | RAS protein activator like 2 | -0.0263805 |
| BMERB1 | bMERB domain containing 1 | -0.0262839 |
| PYGL | phosphorylase, glycogen, liver | -0.0262021 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0257543 |
| ETNK1 | ethanolamine kinase 1 | -0.0255391 |
| CDCP1 | CUB domain containing protein 1 | -0.0253533 |
| TMEM123 | transmembrane protein 123 | -0.0253407 |
| ZNF217 | zinc finger protein 217 | -0.0252242 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0251762 |
| PODXL | podocalyxin-like | -0.0250618 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0248566 |
| ZNF644 | zinc finger protein 644 | -0.0242938 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0242655 |
| RPS6 | ribosomal protein S6 | -0.0242509 |
| MAP4 | microtubule-associated protein 4 | -0.0241534 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0240797 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0240459 |
| ZNF121 | zinc finger protein 121 | -0.0239901 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0239479 |
| RPL5 | ribosomal protein L5 | -0.0238183 |
| RPL35A | ribosomal protein L35a | -0.0237688 |
| POM121 | POM121 transmembrane nucleoporin | -0.0237375 |
| RPS23 | ribosomal protein S23 | -0.0237041 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0236745 |
| MATR3 | matrin 3 | -0.0233007 |
| DIAPH3 | diaphanous-related formin 3 | -0.0230768 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0230031 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0227326 |
| FBXO11 | F-box protein 11 | -0.0226638 |
| HJURP | Holliday junction recognition protein | -0.0226615 |
| FLNB | filamin B, beta | -0.0226583 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0226135 |
| KIF18B | kinesin family member 18B | -0.0224384 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0222971 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0221607 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0221245 |
| RASA2 | RAS p21 protein activator 2 | -0.0221241 |
