| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.0872259 |
| INTS6 | integrator complex subunit 6 | 0.0865215 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0689828 |
| LMO7 | LIM domain 7 | 0.0650163 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0649605 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0611523 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0570608 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0547698 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0538536 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0535911 |
| MYO1E | myosin IE | 0.0533818 |
| AREG | amphiregulin | 0.051513 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0515061 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.045868 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457753 |
| ENO1 | enolase 1, (alpha) | 0.04384 |
| KRT19 | keratin 19, type I | 0.037496 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0365217 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0362746 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0350144 |
| FTL | ferritin, light polypeptide | 0.0346992 |
| DSPP | dentin sialophosphoprotein | 0.0340025 |
| FMNL2 | formin-like 2 | 0.0334862 |
| RPS3 | ribosomal protein S3 | 0.0312064 |
| TGM2 | transglutaminase 2 | 0.0304314 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0303964 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0297872 |
| MT2A | metallothionein 2A | 0.0291744 |
| MYO5B | myosin VB | 0.0289899 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0288025 |
| TXNIP | thioredoxin interacting protein | 0.0281997 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0280401 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271325 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0268311 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0265551 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.026299 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0259594 |
| CTBP2 | C-terminal binding protein 2 | 0.0257082 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0256109 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0254244 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0249481 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0249295 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0249 |
| TPI1 | triosephosphate isomerase 1 | 0.0247578 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0247313 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0246351 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0246256 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0242221 |
| ATP11A | ATPase, class VI, type 11A | 0.0241419 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.023659 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0231796 |
| OXSR1 | oxidative stress responsive 1 | 0.0230473 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227427 |
| RPS12 | ribosomal protein S12 | 0.0227265 |
| RPS18 | ribosomal protein S18 | 0.0223698 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0214168 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0214167 |
| SEPTIN9 | septin 9 | 0.0212418 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0212288 |
| CD44 | CD44 molecule (Indian blood group) | 0.0209064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.020608 |
| ARRDC3 | arrestin domain containing 3 | 0.0204281 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0203993 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0203607 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0202782 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0202567 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0199101 |
| RPLP0 | ribosomal protein, large, P0 | 0.0197184 |
| WWC1 | WW and C2 domain containing 1 | 0.0193844 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192072 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0190444 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0190218 |
| SIK3 | SIK family kinase 3 | 0.0184243 |
| SON | SON DNA binding protein | 0.0183712 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0182699 |
| NRDC | nardilysin convertase | 0.018248 |
| SET | SET nuclear proto-oncogene | 0.0180379 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0180367 |
| PCDH1 | protocadherin 1 | 0.0180094 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0178958 |
| ZNF331 | zinc finger protein 331 | 0.01786 |
| HOMER1 | homer scaffolding protein 1 | 0.0178389 |
| LYST | lysosomal trafficking regulator | 0.0177695 |
| AVPI1 | arginine vasopressin-induced 1 | 0.0176272 |
| PFN1 | profilin 1 | 0.0175468 |
| ADM | adrenomedullin | 0.0175456 |
| SFTPA2 | surfactant protein A2 | 0.0174116 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0173263 |
| NDRG1 | N-myc downstream regulated 1 | 0.0172967 |
| FOSL2 | FOS-like antigen 2 | 0.017228 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0172126 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0171874 |
| RPS8 | ribosomal protein S8 | 0.0168643 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0168424 |
| VEGFA | vascular endothelial growth factor A | 0.0168318 |
| B2M | beta-2-microglobulin | 0.0167395 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0166511 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0165326 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0164196 |
| CD9 | CD9 molecule | 0.0163847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC4 | mucin 4, cell surface associated | -0.148946 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116386 |
| TMSB4X | thymosin beta 4, X-linked | -0.0973416 |
| LAMB3 | laminin, beta 3 | -0.0964433 |
| TPM4 | tropomyosin 4 | -0.0907812 |
| FAM3C | family with sequence similarity 3, member C | -0.0882765 |
| EMP1 | epithelial membrane protein 1 | -0.0814767 |
| RUNX1 | runt-related transcription factor 1 | -0.0696176 |
| RBM39 | RNA binding motif protein 39 | -0.0683393 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0645755 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0643364 |
| KRT17 | keratin 17, type I | -0.0631756 |
| LAMA4 | laminin, alpha 4 | -0.0622738 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0599396 |
| AHNAK | AHNAK nucleoprotein | -0.0598525 |
| HLA-C | major histocompatibility complex, class I, C | -0.0589003 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0582649 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0582358 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0580894 |
| VCL | vinculin | -0.0576963 |
| ACTG1 | actin gamma 1 | -0.0575621 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0568415 |
| ANXA2 | annexin A2 | -0.0566265 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0549572 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0547231 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0544227 |
| JMJD1C | jumonji domain containing 1C | -0.053002 |
| HLA-B | major histocompatibility complex, class I, B | -0.0523534 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0519509 |
| OSMR | oncostatin M receptor | -0.0502593 |
| PLAT | plasminogen activator, tissue | -0.0502189 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0500428 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0494879 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0491775 |
| FN1 | fibronectin 1 | -0.0490988 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0456409 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0454966 |
| RTN4 | reticulon 4 | -0.0450608 |
| TAPBP | TAP binding protein (tapasin) | -0.0447019 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0446435 |
| CD2AP | CD2-associated protein | -0.0445574 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0444734 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0442698 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0438843 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0437817 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0436682 |
| KRT8 | keratin 8, type II | -0.0433477 |
| DIAPH3 | diaphanous-related formin 3 | -0.0424943 |
| PARD3 | par-3 family cell polarity regulator | -0.0420166 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0418381 |
| KRT7 | keratin 7, type II | -0.0417494 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0415412 |
| CEP95 | centrosomal protein 95kDa | -0.0414646 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0403503 |
| EGR1 | early growth response 1 | -0.0397891 |
| NF1 | neurofibromin 1 | -0.0395464 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0395003 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0393463 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0393378 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0390592 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0386415 |
| PDLIM5 | PDZ and LIM domain 5 | -0.038301 |
| CANX | calnexin | -0.0376349 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374416 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0370781 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0370322 |
| CLTC | clathrin, heavy chain (Hc) | -0.0366449 |
| AFAP1 | actin filament associated protein 1 | -0.0363898 |
| ACTN4 | actinin, alpha 4 | -0.0362526 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0359167 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0358301 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0356748 |
| TXNRD1 | thioredoxin reductase 1 | -0.0355117 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0354835 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0353267 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0351672 |
| IL6ST | interleukin 6 signal transducer | -0.035148 |
| SBF2 | SET binding factor 2 | -0.0350814 |
| EFNA5 | ephrin-A5 | -0.0339727 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0339379 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0337772 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0337459 |
| HMGA1 | high mobility group AT-hook 1 | -0.0337247 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0337165 |
| ITGB4 | integrin, beta 4 | -0.0337102 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0335918 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0332426 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0327573 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0327332 |
| GOLGA4 | golgin A4 | -0.0324445 |
| RIOK3 | RIO kinase 3 | -0.0323898 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0323428 |
| SLMAP | sarcolemma associated protein | -0.0320658 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0318897 |
| WDR45B | WD repeat domain 45B | -0.031678 |
| DAPK1 | death-associated protein kinase 1 | -0.0314778 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0313837 |
| PTK2 | protein tyrosine kinase 2 | -0.0313355 |
| RLF | rearranged L-myc fusion | -0.0313196 |
| CDCP1 | CUB domain containing protein 1 | -0.0311446 |
