| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.238215 |
| ZNF608 | zinc finger protein 608 | 0.0966992 |
| EGFR | epidermal growth factor receptor | 0.0872966 |
| EZR | ezrin | 0.0856872 |
| PDGFC | platelet derived growth factor C | 0.0810018 |
| PRELID2 | PRELI domain containing 2 | 0.0806977 |
| HDAC9 | histone deacetylase 9 | 0.0740082 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0707817 |
| ECT2 | epithelial cell transforming 2 | 0.0649326 |
| POTEF | POTE ankyrin domain family, member F | 0.0578775 |
| EFNA5 | ephrin-A5 | 0.0576256 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0478764 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0477054 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0471446 |
| SMYD3 | SET and MYND domain containing 3 | 0.047018 |
| FNIP1 | folliculin interacting protein 1 | 0.0453517 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0443896 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.04431 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0404129 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0397638 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0397396 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0388373 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0349984 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.034425 |
| CREBBP | CREB binding protein | 0.0337077 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0334336 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.032639 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0315658 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0312968 |
| YAP1 | Yes-associated protein 1 | 0.0312818 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0309848 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0307977 |
| ZNF644 | zinc finger protein 644 | 0.0306179 |
| CUL3 | cullin 3 | 0.0287452 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0286487 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0278003 |
| MED13 | mediator complex subunit 13 | 0.0277664 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0277168 |
| SMAD3 | SMAD family member 3 | 0.0269496 |
| RPL3 | ribosomal protein L3 | 0.026918 |
| GLI3 | GLI family zinc finger 3 | 0.0266009 |
| ZNF217 | zinc finger protein 217 | 0.0264078 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0263307 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0262097 |
| VMP1 | vacuole membrane protein 1 | 0.0259493 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0258378 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0253973 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0252751 |
| AFDN | afadin, adherens junction formation factor | 0.0250693 |
| ZNF638 | zinc finger protein 638 | 0.024608 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0243141 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0242879 |
| TXNRD1 | thioredoxin reductase 1 | 0.0237905 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0237704 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0234146 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0233846 |
| ATP9B | ATPase, class II, type 9B | 0.0230246 |
| ZNF148 | zinc finger protein 148 | 0.0229763 |
| PRDX2 | peroxiredoxin 2 | 0.022958 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.022763 |
| WASHC4 | WASH complex subunit 4 | 0.0226373 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.0224953 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0219484 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.0219054 |
| USP34 | ubiquitin specific peptidase 34 | 0.0217247 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.021677 |
| PFN1 | profilin 1 | 0.0215633 |
| MYEOV | myeloma overexpressed | 0.0214004 |
| FER1L6 | fer-1-like family member 6 | 0.0213474 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0213403 |
| DST | dystonin | 0.021333 |
| BRD2 | bromodomain containing 2 | 0.0211419 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.021015 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0210124 |
| TRIM24 | tripartite motif containing 24 | 0.0209461 |
| ATM | ATM serine/threonine kinase | 0.0208771 |
| PMM2 | phosphomannomutase 2 | 0.0208625 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0207332 |
| SMAD6 | SMAD family member 6 | 0.0205399 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.020441 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0203987 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0202154 |
| TRRAP | transformation/transcription domain-associated protein | 0.0201521 |
| AATF | apoptosis antagonizing transcription factor | 0.0201437 |
| CENPE | centromere protein E, 312kDa | 0.0201121 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0200839 |
| KIF4A | kinesin family member 4A | 0.0199866 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.0196926 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0196485 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0195405 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0195223 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0194866 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0192645 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.019173 |
| PCBP2 | poly(rC) binding protein 2 | 0.0191565 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0191451 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0190823 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0190521 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0190497 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0189605 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.23192 |
| BMP10 | bone morphogenetic protein 10 | -0.157282 |
| AHNAK | AHNAK nucleoprotein | -0.133943 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.104 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0903629 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0799878 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0795999 |
| TMSB4X | thymosin beta 4, X-linked | -0.0763838 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0720192 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0720002 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.059542 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0558988 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.05534 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0542252 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0535004 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0499747 |
| MSI2 | musashi RNA-binding protein 2 | -0.0483914 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0482932 |
| NEBL | nebulette | -0.047181 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0470604 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0451659 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0439448 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0431817 |
| RHOA | ras homolog family member A | -0.0426886 |
| MKI67 | marker of proliferation Ki-67 | -0.0411581 |
| RPL34 | ribosomal protein L34 | -0.0390244 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0389306 |
| FLNB | filamin B, beta | -0.0387127 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0379016 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0368123 |
| RLF | rearranged L-myc fusion | -0.0363962 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0361685 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0361537 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0353806 |
| RPL4 | ribosomal protein L4 | -0.0349333 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034537 |
| S100A6 | S100 calcium binding protein A6 | -0.0342157 |
| GNAS | GNAS complex locus | -0.0339187 |
| CCND1 | cyclin D1 | -0.0332169 |
| SFMBT1 | Scm-like with four mbt domains 1 | -0.0326543 |
| BCOR | BCL6 corepressor | -0.0321135 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0320959 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0319285 |
| RPL26 | ribosomal protein L26 | -0.0314141 |
| RPL35A | ribosomal protein L35a | -0.0313663 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0307152 |
| PDE7B | phosphodiesterase 7B | -0.0305268 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0301862 |
| LDHA | lactate dehydrogenase A | -0.0297972 |
| HLA-B | major histocompatibility complex, class I, B | -0.0297858 |
| EXOC6B | exocyst complex component 6B | -0.0296396 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0293061 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0293061 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0292001 |
| MED13L | mediator complex subunit 13-like | -0.029128 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0290996 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0288366 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0286524 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0286442 |
| SEPTIN9 | septin 9 | -0.0284057 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0280399 |
| ZNF609 | zinc finger protein 609 | -0.0279658 |
| RPS6 | ribosomal protein S6 | -0.0279149 |
| MATR3 | matrin 3 | -0.0276552 |
| EVI5 | ecotropic viral integration site 5 | -0.0275757 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0273884 |
| ITGA10 | integrin, alpha 10 | -0.0271716 |
| RPL5 | ribosomal protein L5 | -0.026997 |
| QKI | QKI, KH domain containing, RNA binding | -0.0266544 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0265382 |
| RPS25 | ribosomal protein S25 | -0.0265083 |
| RPS8 | ribosomal protein S8 | -0.0263549 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263326 |
| DSTN | destrin (actin depolymerizing factor) | -0.0263284 |
| RPS24 | ribosomal protein S24 | -0.0260377 |
| NFIA | nuclear factor I/A | -0.0259858 |
| TCF12 | transcription factor 12 | -0.0259207 |
| TAOK1 | TAO kinase 1 | -0.0258863 |
| DIAPH3 | diaphanous-related formin 3 | -0.025376 |
| ADAR | adenosine deaminase, RNA-specific | -0.0251557 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0249558 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0248553 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0247488 |
| ZNF106 | zinc finger protein 106 | -0.024402 |
| RIGI | RNA sensor RIG-I | -0.0243854 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0242273 |
| DENND1A | DENN/MADD domain containing 1A | -0.0242203 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0241032 |
| RPL37 | ribosomal protein L37 | -0.023999 |
| GLI2 | GLI family zinc finger 2 | -0.0239974 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0239841 |
| TPM4 | tropomyosin 4 | -0.023568 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0235551 |
| PLXNA2 | plexin A2 | -0.0235308 |
| CD47 | CD47 molecule | -0.0234158 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233795 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0231226 |
| USP3 | ubiquitin specific peptidase 3 | -0.0228791 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0226665 |
| GPHN | gephyrin | -0.0225799 |
