| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137195 |
| VCL | vinculin | 0.124046 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.113 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0730811 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0630918 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0493276 |
| OGA | O-GlcNAcase | 0.0478048 |
| ADM | adrenomedullin | 0.0474952 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0472241 |
| VMP1 | vacuole membrane protein 1 | 0.0457172 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0426208 |
| HDAC9 | histone deacetylase 9 | 0.0421025 |
| MYOF | myoferlin | 0.0418911 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0410486 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0402811 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0396398 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.038736 |
| DUSP10 | dual specificity phosphatase 10 | 0.0385542 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0374219 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0372485 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0363897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0355221 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0354534 |
| SDC4 | syndecan 4 | 0.0344401 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0339763 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0329649 |
| CTSB | cathepsin B | 0.0316177 |
| STC1 | stanniocalcin 1 | 0.0314079 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0313793 |
| SERINC1 | serine incorporator 1 | 0.0309944 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0305809 |
| FNIP1 | folliculin interacting protein 1 | 0.0304039 |
| SFTPA2 | surfactant protein A2 | 0.0303293 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0302576 |
| LDHA | lactate dehydrogenase A | 0.0300429 |
| COL1A1 | collagen, type I, alpha 1 | 0.0299342 |
| ENO1 | enolase 1, (alpha) | 0.0295323 |
| FAM20C | family with sequence similarity 20, member C | 0.0283755 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0282195 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0280794 |
| CORO1C | coronin, actin binding protein, 1C | 0.0277024 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0267326 |
| SMAD3 | SMAD family member 3 | 0.0267319 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0263384 |
| THBS2 | thrombospondin 2 | 0.0249229 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248107 |
| CALR | calreticulin | 0.0247777 |
| ANXA2 | annexin A2 | 0.0245377 |
| CD164 | CD164 molecule, sialomucin | 0.0239766 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0236769 |
| INTS6 | integrator complex subunit 6 | 0.0231126 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.023028 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0228425 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0227915 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0222726 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0222621 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0221645 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0219849 |
| ACTN1 | actinin, alpha 1 | 0.021872 |
| UBC | ubiquitin C | 0.021593 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0215423 |
| COL1A2 | collagen, type I, alpha 2 | 0.021478 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0214389 |
| BICC1 | BicC family RNA binding protein 1 | 0.0208909 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0202469 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0198617 |
| CREBRF | CREB3 regulatory factor | 0.0197692 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0197174 |
| CEP250 | centrosomal protein 250kDa | 0.0195106 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0194931 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0191444 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0191104 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0189348 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0189134 |
| WFDC10B | WAP four-disulfide core domain 10B | 0.0188811 |
| ZNF608 | zinc finger protein 608 | 0.0188597 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0188544 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0187185 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0185644 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0185413 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0184571 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0182678 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0180855 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0178479 |
| CTSA | cathepsin A | 0.0177486 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0177373 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0176532 |
| SP100 | SP100 nuclear antigen | 0.017622 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0175591 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0174954 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.017371 |
| CALD1 | caldesmon 1 | 0.0172716 |
| SFXN3 | sideroflexin 3 | 0.017229 |
| MLPH | melanophilin | 0.0169786 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0169515 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0168943 |
| IDS | iduronate 2-sulfatase | 0.0167703 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0166654 |
| ERBIN | erbb2 interacting protein | 0.0162846 |
| CUL4B | cullin 4B | 0.0161508 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.216276 |
| VIM | vimentin | -0.187109 |
| VEGFA | vascular endothelial growth factor A | -0.104384 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0941675 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.088888 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0819966 |
| NDRG1 | N-myc downstream regulated 1 | -0.0773942 |
| CADM1 | cell adhesion molecule 1 | -0.0731778 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0729988 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0683619 |
| RPS6 | ribosomal protein S6 | -0.0681048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0666013 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0656376 |
| RAI14 | retinoic acid induced 14 | -0.0654875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0643595 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0638608 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0638291 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0599242 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.059164 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0579138 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0577261 |
| ZNF292 | zinc finger protein 292 | -0.0560922 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0559374 |
| C3 | complement component 3 | -0.0554737 |
| TPM4 | tropomyosin 4 | -0.0549147 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0532014 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0525308 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0514831 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0491812 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0453892 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0442226 |
| MMP12 | matrix metallopeptidase 12 | -0.0434858 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0424972 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0423745 |
| EGFR | epidermal growth factor receptor | -0.0418308 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0409455 |
| CLMP | CXADR-like membrane protein | -0.0404266 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0395084 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0392772 |
| TAPBP | TAP binding protein (tapasin) | -0.0377482 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0376818 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0374984 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.037456 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0373913 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0367539 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0364573 |
| CD44 | CD44 molecule (Indian blood group) | -0.0362419 |
| HLA-B | major histocompatibility complex, class I, B | -0.0359842 |
| EFNA5 | ephrin-A5 | -0.0358537 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0358431 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0355524 |
| FOXP1 | forkhead box P1 | -0.0352282 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350994 |
| RPS23 | ribosomal protein S23 | -0.0349045 |
| RPL5 | ribosomal protein L5 | -0.0344438 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0341984 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0339191 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0335193 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0332842 |
| DIAPH2 | diaphanous-related formin 2 | -0.0329339 |
| RNF213 | ring finger protein 213 | -0.0324514 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0323862 |
| GNAS | GNAS complex locus | -0.0319409 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0311418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0311145 |
| FTL | ferritin, light polypeptide | -0.030899 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0307831 |
| GLIS3 | GLIS family zinc finger 3 | -0.0307736 |
| PKM | pyruvate kinase, muscle | -0.0304506 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0304455 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0303959 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0303865 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0300864 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0300038 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0297866 |
| CD99 | CD99 molecule | -0.0295133 |
| CANX | calnexin | -0.0294704 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0293116 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0291969 |
| RPLP1 | ribosomal protein, large, P1 | -0.0288523 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0288243 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0287705 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0287424 |
| PDE10A | phosphodiesterase 10A | -0.028147 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -0.0280106 |
| GOLGA4 | golgin A4 | -0.0277945 |
| RPS8 | ribosomal protein S8 | -0.0276168 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0274692 |
| BBX | bobby sox homolog (Drosophila) | -0.0274668 |
| ARF4 | ADP-ribosylation factor 4 | -0.0273288 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0272245 |
| NRP1 | neuropilin 1 | -0.0271319 |
| HMGA1 | high mobility group AT-hook 1 | -0.0270133 |
| CDC27 | cell division cycle 27 | -0.0269458 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0267529 |
| TPM1 | tropomyosin 1 (alpha) | -0.0266892 |
| PTEN | phosphatase and tensin homolog | -0.026629 |
| HLA-A | major histocompatibility complex, class I, A | -0.0266192 |
| MAP4 | microtubule-associated protein 4 | -0.0264317 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0264265 |
