| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0754901 |
| SMAD3 | SMAD family member 3 | 0.0671111 |
| CD44 | CD44 molecule (Indian blood group) | 0.0664904 |
| PRKCA | protein kinase C, alpha | 0.0616741 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.060463 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0555588 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0552331 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0546571 |
| FMNL2 | formin-like 2 | 0.0539023 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0444593 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0410448 |
| SVIL | supervillin | 0.0408112 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0404879 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.039736 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0396637 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0394037 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0393309 |
| ANO6 | anoctamin 6 | 0.039222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0381552 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0378937 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0372451 |
| SIK2 | salt-inducible kinase 2 | 0.0363597 |
| SMYD3 | SET and MYND domain containing 3 | 0.0362562 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0359227 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0352789 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0342484 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0342317 |
| FMN1 | formin 1 | 0.0335686 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0328277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327999 |
| YAP1 | Yes-associated protein 1 | 0.0325442 |
| POTEF | POTE ankyrin domain family, member F | 0.0317485 |
| OXSR1 | oxidative stress responsive 1 | 0.0313722 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0307944 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0301526 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0301265 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0294169 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0294094 |
| JMJD1C | jumonji domain containing 1C | 0.0292681 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0288345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0285517 |
| KIF5B | kinesin family member 5B | 0.0285396 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.028112 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.028073 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0280365 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.027991 |
| PRELID2 | PRELI domain containing 2 | 0.0277322 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0273595 |
| CPNE1 | copine I | 0.0272687 |
| CENPF | centromere protein F, 350/400kDa | 0.026798 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0264775 |
| CD59 | CD59 molecule, complement regulatory protein | 0.026456 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0262199 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0259499 |
| ATXN7 | ataxin 7 | 0.0257928 |
| MKI67 | marker of proliferation Ki-67 | 0.0256268 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0255341 |
| SEPTIN9 | septin 9 | 0.025355 |
| STK24 | serine/threonine kinase 24 | 0.02532 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0248004 |
| WWOX | WW domain containing oxidoreductase | 0.0242666 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0242648 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0242575 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.024089 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0240226 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0237253 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0236994 |
| LATS2 | large tumor suppressor kinase 2 | 0.0236226 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0231838 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0231351 |
| MED13L | mediator complex subunit 13-like | 0.0230541 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229177 |
| CUL3 | cullin 3 | 0.0226493 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0224806 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0221245 |
| ECT2 | epithelial cell transforming 2 | 0.0219138 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0219109 |
| TBC1D5 | TBC1 domain family, member 5 | 0.021904 |
| SGO2 | shugoshin 2 | 0.0214582 |
| UTRN | utrophin | 0.0211606 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0210754 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0210545 |
| CCDC50 | coiled-coil domain containing 50 | 0.0210073 |
| TJP1 | tight junction protein 1 | 0.0208637 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0208227 |
| INTS6 | integrator complex subunit 6 | 0.0206388 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0205018 |
| RNF217 | ring finger protein 217 | 0.0204229 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0204129 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0204096 |
| VCL | vinculin | 0.0203749 |
| FBXO38 | F-box protein 38 | 0.0201004 |
| RNF145 | ring finger protein 145 | 0.0200806 |
| TMEM245 | transmembrane protein 245 | 0.0200196 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0199715 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0198465 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0198175 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0198008 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0194493 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0194227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.161201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117724 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109658 |
| TMSB10 | thymosin beta 10 | -0.0959664 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0955946 |
| VIM | vimentin | -0.0835248 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0762233 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0652194 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0636301 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.057004 |
| AHNAK | AHNAK nucleoprotein | -0.0540448 |
| MT2A | metallothionein 2A | -0.0536257 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0524573 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0522702 |
| PTMA | prothymosin, alpha | -0.0518134 |
| NF1 | neurofibromin 1 | -0.0499862 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0496961 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0466128 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0456087 |
| RIGI | RNA sensor RIG-I | -0.0455843 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0450698 |
| RBM39 | RNA binding motif protein 39 | -0.0433609 |
| ATG7 | autophagy related 7 | -0.0430586 |
| LDHA | lactate dehydrogenase A | -0.0425681 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0416426 |
| ANGPTL4 | angiopoietin-like 4 | -0.0413121 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0408891 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.040193 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0397013 |
| SQSTM1 | sequestosome 1 | -0.03884 |
| HLA-B | major histocompatibility complex, class I, B | -0.0387615 |
| GOLGA4 | golgin A4 | -0.0381027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0370437 |
| HM13 | histocompatibility (minor) 13 | -0.0369826 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.036889 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0360268 |
| ITSN2 | intersectin 2 | -0.0359412 |
| TPM4 | tropomyosin 4 | -0.0352116 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0351032 |
| HDAC9 | histone deacetylase 9 | -0.0347983 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0346584 |
| RPL26 | ribosomal protein L26 | -0.0338877 |
| SDC4 | syndecan 4 | -0.0338449 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0335447 |
| GOLGB1 | golgin B1 | -0.0335338 |
| S100A10 | S100 calcium binding protein A10 | -0.0332713 |
| CAVIN1 | caveolae associated protein 1 | -0.033088 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0329597 |
| NKTR | natural killer cell triggering receptor | -0.032395 |
| RIN2 | Ras and Rab interactor 2 | -0.0322227 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.03187 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0318439 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0316001 |
| TMEM263 | transmembrane protein 263 | -0.031476 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0313904 |
| GNAS | GNAS complex locus | -0.0313636 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0313559 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0311861 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0310778 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310297 |
| RBM25 | RNA binding motif protein 25 | -0.0308324 |
| RPL35A | ribosomal protein L35a | -0.0306571 |
| HLA-E | major histocompatibility complex, class I, E | -0.030537 |
| MED13 | mediator complex subunit 13 | -0.0305153 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.030453 |
| CAPRIN2 | caprin family member 2 | -0.0301339 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0300643 |
| EGR1 | early growth response 1 | -0.0299551 |
| RSF1 | remodeling and spacing factor 1 | -0.0296049 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.029488 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0293574 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0292491 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0288995 |
| GPC5 | glypican 5 | -0.0288649 |
| GOLGA3 | golgin A3 | -0.0288091 |
| RBM27 | RNA binding motif protein 27 | -0.0287042 |
| ERBIN | erbb2 interacting protein | -0.0286427 |
| HLA-C | major histocompatibility complex, class I, C | -0.028442 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0283755 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283533 |
| ASPH | aspartate beta-hydroxylase | -0.0283355 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281496 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0280437 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0279446 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0279198 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0275632 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0275163 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.027451 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0274027 |
| UBB | ubiquitin B | -0.0273542 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0273004 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0272476 |
| HDLBP | high density lipoprotein binding protein | -0.0269575 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0267908 |
| SETD5 | SET domain containing 5 | -0.0267403 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0264757 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0264634 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0263068 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0262954 |
| SP100 | SP100 nuclear antigen | -0.0261179 |
