| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lumateperone (tosylate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lumateperone (tosylate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.092996 |
| ASPH | aspartate beta-hydroxylase | 0.0883144 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0866318 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0792661 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0768933 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0673609 |
| FAM13A | family with sequence similarity 13, member A | 0.0633088 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0579351 |
| INTS6 | integrator complex subunit 6 | 0.0570111 |
| STC2 | stanniocalcin 2 | 0.056712 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.055966 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0558319 |
| LMNA | lamin A/C | 0.0555541 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0549119 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0540906 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0527565 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0508772 |
| MYOF | myoferlin | 0.0502688 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0490958 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0483448 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0463197 |
| NDRG1 | N-myc downstream regulated 1 | 0.0447764 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0423159 |
| EZR | ezrin | 0.0421726 |
| ENO1 | enolase 1, (alpha) | 0.0405443 |
| PLIN2 | perilipin 2 | 0.0395741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0395029 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0364289 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.036406 |
| SPAG9 | sperm associated antigen 9 | 0.0363482 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.035931 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0357178 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0357117 |
| PTMA | prothymosin, alpha | 0.0355596 |
| CANX | calnexin | 0.0350943 |
| NRG1 | neuregulin 1 | 0.0349583 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0341869 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0335557 |
| SQSTM1 | sequestosome 1 | 0.033494 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0333831 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0325189 |
| CADM1 | cell adhesion molecule 1 | 0.031853 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0317257 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0314621 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0289037 |
| FMNL2 | formin-like 2 | 0.0286038 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0285271 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0282144 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.028049 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0279252 |
| FN1 | fibronectin 1 | 0.0277279 |
| S100A10 | S100 calcium binding protein A10 | 0.0276904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0276497 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276105 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0274807 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.027396 |
| CTBP2 | C-terminal binding protein 2 | 0.0272998 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0269609 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0268283 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0262654 |
| MCL1 | myeloid cell leukemia 1 | 0.0259411 |
| FLNB | filamin B, beta | 0.025332 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0251289 |
| DUSP10 | dual specificity phosphatase 10 | 0.0250313 |
| ATF3 | activating transcription factor 3 | 0.0248542 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0247933 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0238554 |
| AFDN | afadin, adherens junction formation factor | 0.0236413 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0234873 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0233588 |
| JUN | jun proto-oncogene | 0.0228772 |
| XPO1 | exportin 1 | 0.0228126 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0223941 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0212795 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0212491 |
| ANXA2 | annexin A2 | 0.0207103 |
| AHNAK | AHNAK nucleoprotein | 0.0205997 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.020598 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0204933 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0204083 |
| SLC35F3 | solute carrier family 35, member F3 | 0.020202 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.020069 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0200635 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0200189 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0199956 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0199077 |
| ABLIM1 | actin binding LIM protein 1 | 0.0198423 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197763 |
| B2M | beta-2-microglobulin | 0.0197097 |
| SGMS2 | sphingomyelin synthase 2 | 0.0194367 |
| RYBP | RING1 and YY1 binding protein | 0.0193596 |
| EMP1 | epithelial membrane protein 1 | 0.0193403 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0191527 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0191165 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0189441 |
| PGK1 | phosphoglycerate kinase 1 | 0.0188563 |
| LOXL2 | lysyl oxidase-like 2 | 0.018601 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0185886 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0185196 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.256287 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.166642 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.1272 |
| OSMR | oncostatin M receptor | -0.112869 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.106763 |
| NRP1 | neuropilin 1 | -0.0892484 |
| TMEM165 | transmembrane protein 165 | -0.0785521 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0756221 |
| EXT1 | exostosin glycosyltransferase 1 | -0.073286 |
| TMEM156 | transmembrane protein 156 | -0.0706288 |
| SYT1 | synaptotagmin I | -0.0664986 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0639385 |
| MT2A | metallothionein 2A | -0.0639018 |
| GLIS3 | GLIS family zinc finger 3 | -0.063726 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0619932 |
| ITGA1 | integrin, alpha 1 | -0.0613165 |
| ETV6 | ets variant 6 | -0.0553932 |
| HMGA2 | high mobility group AT-hook 2 | -0.0553562 |
| SMOX | spermine oxidase | -0.0548775 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0546402 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0525009 |
| PELO | pelota homolog (Drosophila) | -0.0506253 |
| ETNK1 | ethanolamine kinase 1 | -0.0497702 |
| RUNX2 | runt-related transcription factor 2 | -0.0480641 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0471746 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0466537 |
| PRRC2C | proline-rich coiled-coil 2C | -0.045964 |
| FOXP1 | forkhead box P1 | -0.0453806 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0449003 |
| COG5 | component of oligomeric golgi complex 5 | -0.0448165 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.043906 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0434172 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0422348 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0417356 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0415308 |
| CAB39 | calcium binding protein 39 | -0.0405981 |
| CDCP1 | CUB domain containing protein 1 | -0.0405412 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0405226 |
| FAF2 | Fas associated factor family member 2 | -0.0399131 |
| CD44 | CD44 molecule (Indian blood group) | -0.0398772 |
| KLHL5 | kelch-like family member 5 | -0.0390494 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0380133 |
| ETV1 | ets variant 1 | -0.0376096 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0374415 |
| KSR1 | kinase suppressor of ras 1 | -0.0366442 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0366119 |
| CENPF | centromere protein F, 350/400kDa | -0.0363204 |
| IL6ST | interleukin 6 signal transducer | -0.0356126 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0345841 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0345803 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | -0.0344154 |
| VMP1 | vacuole membrane protein 1 | -0.0344 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0335375 |
| GOLGA4 | golgin A4 | -0.033469 |
| AHR | aryl hydrocarbon receptor | -0.0328394 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0322028 |
| TXNRD1 | thioredoxin reductase 1 | -0.0311849 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0305734 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0303693 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0300083 |
| HPCAL1 | hippocalcin-like 1 | -0.029657 |
| FNBP1 | formin binding protein 1 | -0.0296116 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0291201 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0290065 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0289337 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0288233 |
| CCDC91 | coiled-coil domain containing 91 | -0.0288132 |
| NTN4 | netrin 4 | -0.0286722 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0284858 |
| ADD3 | adducin 3 (gamma) | -0.02844 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0279801 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0278413 |
| SEPTIN9 | septin 9 | -0.0276871 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275809 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0275735 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0274437 |
| SSH1 | slingshot protein phosphatase 1 | -0.0269815 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0268965 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0268097 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0267873 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0267837 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0265919 |
| CDC27 | cell division cycle 27 | -0.0261513 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0260981 |
| FAM3C | family with sequence similarity 3, member C | -0.0259882 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0258852 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0258114 |
| VEGFA | vascular endothelial growth factor A | -0.025737 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0255692 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0253123 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0252684 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0251127 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.025011 |
| EPN2 | epsin 2 | -0.0248822 |
| ZNF644 | zinc finger protein 644 | -0.0248607 |
| MKI67 | marker of proliferation Ki-67 | -0.0248214 |
| EFNA5 | ephrin-A5 | -0.0245304 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0244866 |
| PLPP6 | phospholipid phosphatase 6 | -0.0243827 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0243594 |
