Lumiracoxib Gene Set

Dataset	HMDB Metabolites of Enzymes
Category	physical interactions
Type	metabolite
Description	An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_73044)
External Link	http://www.hmdb.ca/metabolites/HMDB15403
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Genes

6 interacting proteins for the Lumiracoxib metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol	Name
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9