Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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416 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAN aggrecan
ACAT2 acetyl-CoA acetyltransferase 2
ACOT13 acyl-CoA thioesterase 13
ACPT acid phosphatase, testicular
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTN1 actinin, alpha 1
ADAM12 ADAM metallopeptidase domain 12
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL4 adhesion G protein-coupled receptor L4
AEBP1 AE binding protein 1
AGPS alkylglycerone phosphate synthase
AIM1L absent in melanoma 1-like
ANGPTL2 angiopoietin-like 2
ANKRD42 ankyrin repeat domain 42
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
ANTXR1 anthrax toxin receptor 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
APLN apelin
APLNR apelin receptor
ASF1A anti-silencing function 1A histone chaperone
ASMT acetylserotonin O-methyltransferase
ASPN asporin
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATL3 atlastin GTPase 3
ATMIN ATM interactor
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AVEN apoptosis, caspase activation inhibitor
BAG2 BCL2-associated athanogene 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
BHLHE22 basic helix-loop-helix family, member e22
BICC1 BicC family RNA binding protein 1
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BRD7P3 bromodomain containing 7 pseudogene 3
C10ORF12 chromosome 10 open reading frame 12
C11ORF87 chromosome 11 open reading frame 87
C16ORF70 chromosome 16 open reading frame 70
C16ORF87 chromosome 16 open reading frame 87
C17ORF77 chromosome 17 open reading frame 77
C1ORF105 chromosome 1 open reading frame 105
C1QTNF6 C1q and tumor necrosis factor related protein 6
C2CD4A C2 calcium-dependent domain containing 4A
C2ORF69 chromosome 2 open reading frame 69
C4ORF32 chromosome 4 open reading frame 32
C5ORF46 chromosome 5 open reading frame 46
C7ORF49 chromosome 7 open reading frame 49
C8ORF74 chromosome 8 open reading frame 74
C9ORF64 chromosome 9 open reading frame 64
CALD1 caldesmon 1
CASC10 cancer susceptibility candidate 10
CBX2 chromobox homolog 2
CCDC79 coiled-coil domain containing 79
CCDC80 coiled-coil domain containing 80
CCDC83 coiled-coil domain containing 83
CCDC90B coiled-coil domain containing 90B
CCL22 chemokine (C-C motif) ligand 22
CCNA2 cyclin A2
CCNYL1 cyclin Y-like 1
CD200 CD200 molecule
CD34 CD34 molecule
CD99 CD99 molecule
CDC25C cell division cycle 25C
CENPBD1 CENPB DNA-binding domains containing 1
CENPN centromere protein N
CENPW centromere protein W
CEP55 centrosomal protein 55kDa
CETP cholesteryl ester transfer protein, plasma
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CILP2 cartilage intermediate layer protein 2
CLIC4 chloride intracellular channel 4
CLIP1 CAP-GLY domain containing linker protein 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL12A1 collagen, type XII, alpha 1
COL15A1 collagen, type XV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A3 collagen, type VI, alpha 3
CPE carboxypeptidase E
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CREG2 cellular repressor of E1A-stimulated genes 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CT83 cancer/testis antigen 83
CTGF connective tissue growth factor
CTSV cathepsin V
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF17 DDB1 and CUL4 associated factor 17
DCLK3 doublecortin-like kinase 3
DDIAS DNA damage-induced apoptosis suppressor
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DLG2 discs, large homolog 2 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
DPP3 dipeptidyl-peptidase 3
DPT dermatopontin
DSC1 desmocollin 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYSF dysferlin
E2F8 E2F transcription factor 8
EFCAB11 EF-hand calcium binding domain 11
EFHD1 EF-hand domain family, member D1
EIF5B eukaryotic translation initiation factor 5B
EMILIN1 elastin microfibril interfacer 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPT1 ethanolaminephosphotransferase 1
ERCC3 excision repair cross-complementation group 3
ESX1 ESX homeobox 1
ETF1 eukaryotic translation termination factor 1
EXOSC6 exosome component 6
F2R coagulation factor II (thrombin) receptor
FAM133A family with sequence similarity 133, member A
FAM171B family with sequence similarity 171, member B
FAM20C family with sequence similarity 20, member C
FARSB phenylalanyl-tRNA synthetase, beta subunit
FBN1 fibrillin 1
FEM1B fem-1 homolog b (C. elegans)
FGF12 fibroblast growth factor 12
FGF7 fibroblast growth factor 7
FGFR1OP FGFR1 oncogene partner
FIBCD1 fibrinogen C domain containing 1
FIGN fidgetin
FLJ16779 uncharacterized LOC100192386
FOXG1 forkhead box G1
FUCA2 fucosidase, alpha-L- 2, plasma
FURIN furin (paired basic amino acid cleaving enzyme)
GAN gigaxonin
GBX2 gastrulation brain homeobox 2
GDF3 growth differentiation factor 3
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4
GFOD2 glucose-fructose oxidoreductase domain containing 2
GJA5 gap junction protein, alpha 5, 40kDa
GJC3 gap junction protein, gamma 3, 30.2kDa
GLA galactosidase, alpha
GOLGA6C golgin A6 family, member C
GPC6 glypican 6
GPR21 G protein-coupled receptor 21
GPR88 G protein-coupled receptor 88
GRAMD1B GRAM domain containing 1B
GREM1 gremlin 1, DAN family BMP antagonist
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa
GXYLT2 glucoside xylosyltransferase 2
HMHB1 histocompatibility (minor) HB-1
HNRNPR heterogeneous nuclear ribonucleoprotein R
HORMAD2 HORMA domain containing 2
HSPA2 heat shock 70kDa protein 2
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPG2 heparan sulfate proteoglycan 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTRA1 HtrA serine peptidase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ILK integrin-linked kinase
INA internexin neuronal intermediate filament protein, alpha
INHBA inhibin, beta A
IPO7 importin 7
IRX4 iroquois homeobox 4
ISL2 ISL LIM homeobox 2
ITGA11 integrin, alpha 11
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JPH2 junctophilin 2
KARS lysyl-tRNA synthetase
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0319 KIAA0319
KIAA0586 KIAA0586
KIAA1161 KIAA1161
KIAA1755 KIAA1755
KIF1BP KIF1 binding protein
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KIF4B kinesin family member 4B
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
KLKP1 kallikrein pseudogene 1
LAMA4 laminin, alpha 4
LAMB1 laminin, beta 1
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LARP1B La ribonucleoprotein domain family, member 1B
LBH limb bud and heart development
LBX1 ladybird homeobox 1
LCE3A late cornified envelope 3A
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LIN54 lin-54 DREAM MuvB core complex component
LINC00239 long intergenic non-protein coding RNA 239
LINC00310 long intergenic non-protein coding RNA 310
LINC00319 long intergenic non-protein coding RNA 319
LINC00518 long intergenic non-protein coding RNA 518
LINC01465 long intergenic non-protein coding RNA 1465
LINC01551 long intergenic non-protein coding RNA 1551
LINC01555 long intergenic non-protein coding RNA 1555
LOC285627 uncharacterized LOC285627
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC641367 cyclin Y-like 1 pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LRP11 low density lipoprotein receptor-related protein 11
LRRC15 leucine rich repeat containing 15
LUM lumican
LYPD3 LY6/PLAUR domain containing 3
LZTS1 leucine zipper, putative tumor suppressor 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7 microtubule-associated protein 7
MAPK4 mitogen-activated protein kinase 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MARVELD1 MARVEL domain containing 1
MARVELD3 MARVEL domain containing 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCAM melanoma cell adhesion molecule
METTL21A methyltransferase like 21A
METTL5 methyltransferase like 5
METTL8 methyltransferase like 8
MFRP membrane frizzled-related protein
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MGC16025 uncharacterized LOC85009
MID1 midline 1
MIMT1 MER1 repeat containing imprinted transcript 1 (non-protein coding)
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MMS22L MMS22-like, DNA repair protein
MOXD1 monooxygenase, DBH-like 1
MPHOSPH6 M-phase phosphoprotein 6
MRPL30 mitochondrial ribosomal protein L30
MRVI1 murine retrovirus integration site 1 homolog
MT1L metallothionein 1L (gene/pseudogene)
MTFR2 mitochondrial fission regulator 2
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTMR2 myotubularin related protein 2
MXRA5 matrix-remodelling associated 5
MYLK myosin light chain kinase
N4BP3 NEDD4 binding protein 3
NAF1 nuclear assembly factor 1 ribonucleoprotein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NCL nucleolin
NGRN neugrin, neurite outgrowth associated
NID1 nidogen 1
NID2 nidogen 2 (osteonidogen)
NOTCH3 notch 3
NPFFR2 neuropeptide FF receptor 2
NPHP3-AS1 NPHP3 antisense RNA 1
NRARP NOTCH-regulated ankyrin repeat protein
NUTF2 nuclear transport factor 2
NXPH2 neurexophilin 2
OLFML2B olfactomedin-like 2B
OR11H12 olfactory receptor, family 11, subfamily H, member 12
OR52E4 olfactory receptor, family 52, subfamily E, member 4
OR56A1 olfactory receptor, family 56, subfamily A, member 1
OR56A3 olfactory receptor, family 56, subfamily A, member 3
ORC2 origin recognition complex, subunit 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAQR7 progestin and adipoQ receptor family member VII
PAWR PRKC, apoptosis, WT1, regulator
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDH12 protocadherin 12
PCDH18 protocadherin 18
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PEG3 paternally expressed 3
PGM2L1 phosphoglucomutase 2-like 1
PICALM phosphatidylinositol binding clathrin assembly protein
PKD2L2 polycystic kidney disease 2-like 2
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLEK2 pleckstrin 2
PLN phospholamban
PLVAP plasmalemma vesicle associated protein
PLXNA4 plexin A4
PMEPA1 prostate transmembrane protein, androgen induced 1
POSTN periostin, osteoblast specific factor
PP14571 uncharacterized LOC100130449
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPT2 palmitoyl-protein thioesterase 2
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDM14 PR domain containing 14
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRND prion protein 2 (dublet)
PRR34 proline rich 34
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PRRT1 proline-rich transmembrane protein 1
PRSS23 protease, serine, 23
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTGES prostaglandin E synthase
PTGFRN prostaglandin F2 receptor inhibitor
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PXDN peroxidasin
PYGL phosphorylase, glycogen, liver
R3HDML R3H domain containing-like
RAB11A RAB11A, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB6A RAB6A, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RAET1L retinoic acid early transcript 1L
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RFPL3 ret finger protein-like 3
RFX8 RFX family member 8, lacking RFX DNA binding domain
RHOD ras homolog family member D
RHOV ras homolog family member V
RND3 Rho family GTPase 3
RNF121 ring finger protein 121
RPRML reprimo-like
RTN4IP1 reticulon 4 interacting protein 1
RXFP3 relaxin/insulin-like family peptide receptor 3
SCARF2 scavenger receptor class F, member 2
SEMG2 semenogelin II
SEPT5 septin 5
SERTAD4 SERTA domain containing 4
SFRP4 secreted frizzled-related protein 4
SKIDA1 SKI/DACH domain containing 1
SLC25A43 solute carrier family 25, member 43
SLC38A9 solute carrier family 38, member 9
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLN sarcolipin
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMOC2 SPARC related modular calcium binding 2
SMTN smoothelin
SNORA2A small nucleolar RNA, H/ACA box 2A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SOX18 SRY (sex determining region Y)-box 18
SPANXC SPANX family, member C
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPATA31A5 SPATA31 subfamily A, member 5
SPATA31A6 SPATA31 subfamily A, member 6
SPHK1 sphingosine kinase 1
SPNS2 spinster homolog 2 (Drosophila)
SPRY3 sprouty homolog 3 (Drosophila)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRGN serglycin
SULF2 sulfatase 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAGLN transgelin
TARM1 T cell-interacting, activating receptor on myeloid cells 1
TAS1R2 taste receptor, type 1, member 2
TAS2R30 taste receptor, type 2, member 30
TBATA thymus, brain and testes associated
TBX18 T-box 18
TCP1 t-complex 1
TCP10L t-complex 10-like
TEX37 testis expressed 37
TEX40 testis expressed 40
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TINCR tissue differentiation-inducing non-protein coding RNA
TIPIN TIMELESS interacting protein
TLDC1 TBC/LysM-associated domain containing 1
TLK1 tousled-like kinase 1
TM4SF19 transmembrane 4 L six family member 19
TMEM126A transmembrane protein 126A
TMOD3 tropomodulin 3 (ubiquitous)
TMSB4Y thymosin beta 4, Y-linked
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1
TNS4 tensin 4
TP53I3 tumor protein p53 inducible protein 3
TPM1 tropomyosin 1 (alpha)
TPRKB TP53RK binding protein
TRIM6 tripartite motif containing 6
TRIM6-TRIM34 TRIM6-TRIM34 readthrough
TRIM7 tripartite motif containing 7
TRIP12 thyroid hormone receptor interactor 12
TRIP4 thyroid hormone receptor interactor 4
TSPAN14 tetraspanin 14
TSPAN16 tetraspanin 16
TTL tubulin tyrosine ligase
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TUBA4A tubulin, alpha 4a
TUBB3 tubulin, beta 3 class III
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UNC5B unc-5 homolog B (C. elegans)
UPK1B uroplakin 1B
USP47 ubiquitin specific peptidase 47
VANGL1 VANGL planar cell polarity protein 1
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
WISP2 WNT1 inducible signaling pathway protein 2
WNT2 wingless-type MMTV integration site family member 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZFY zinc finger protein, Y-linked
ZNF697 zinc finger protein 697
ZWILCH zwilch kinetochore protein