Lung adenocarcinoma_LUAD_TCGA-55-6982-01A-11R-1949-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung adenocarcinoma_LUAD (The Cancer Genome Atlas)
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348 genes with high or low expression in Lung adenocarcinoma_LUAD_TCGA-55-6982-01A-11R-1949-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABHD11 abhydrolase domain containing 11
ACO2 aconitase 2, mitochondrial
ACOT6 acyl-CoA thioesterase 6
ACSL1 acyl-CoA synthetase long-chain family member 1
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADSS adenylosuccinate synthase
AGMAT agmatine ureohydrolase (agmatinase)
AGRN agrin
AIM1L absent in melanoma 1-like
AMDHD2 amidohydrolase domain containing 2
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
APOOL apolipoprotein O-like
AREG amphiregulin
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARSJ arylsulfatase family, member J
ASCC3 activating signal cointegrator 1 complex subunit 3
ASCL3 achaete-scute family bHLH transcription factor 3
ASL argininosuccinate lyase
ATAD3A ATPase family, AAA domain containing 3A
ATP5L2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
AURKAIP1 aurora kinase A interacting protein 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BRD9 bromodomain containing 9
C10ORF113 chromosome 10 open reading frame 113
C14ORF1 chromosome 14 open reading frame 1
C15ORF32 chromosome 15 open reading frame 32
C17ORF102 chromosome 17 open reading frame 102
C1ORF100 chromosome 1 open reading frame 100
C1ORF27 chromosome 1 open reading frame 27
C2ORF72 chromosome 2 open reading frame 72
C9 complement component 9
CALR3 calreticulin 3
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAND1 cullin-associated and neddylation-dissociated 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC127 coiled-coil domain containing 127
CCDC47 coiled-coil domain containing 47
CCDC83 coiled-coil domain containing 83
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD38 CD38 molecule
CDHR5 cadherin-related family member 5
CDK11B cyclin-dependent kinase 11B
CDK4 cyclin-dependent kinase 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP72 centrosomal protein 72kDa
CFH complement factor H
CHPF chondroitin polymerizing factor
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CILP2 cartilage intermediate layer protein 2
CISD2 CDGSH iron sulfur domain 2
CKB creatine kinase, brain
CLCN7 chloride channel, voltage-sensitive 7
CLDN3 claudin 3
CLDN4 claudin 4
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLTC clathrin, heavy chain (Hc)
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CMTM1 CKLF-like MARVEL transmembrane domain containing 1
CMTM3 CKLF-like MARVEL transmembrane domain containing 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNOT2 CCR4-NOT transcription complex, subunit 2
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL8A2 collagen, type VIII, alpha 2
COMP cartilage oligomeric matrix protein
CPM carboxypeptidase M
CPTP ceramide-1-phosphate transfer protein
CPVL carboxypeptidase, vitellogenic-like
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSA cathepsin A
CTSD cathepsin D
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCTN2 dynactin 2 (p50)
DDIT3 DNA-damage-inducible transcript 3
DNAH5 dynein, axonemal, heavy chain 5
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNM3 dynamin 3
DOK5 docking protein 5
DPP4 dipeptidyl-peptidase 4
DROSHA drosha, ribonuclease type III
DSEL dermatan sulfate epimerase-like
DTX3 deltex 3, E3 ubiquitin ligase
DUSP3 dual specificity phosphatase 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFNA2 ephrin-A2
EFR3A EFR3 homolog A (S. cerevisiae)
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF4H eukaryotic translation initiation factor 4H
ELOVL1 ELOVL fatty acid elongase 1
ENO2 enolase 2 (gamma, neuronal)
ENOPH1 enolase-phosphatase 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPDR1 ependymin related 1
EPHA10 EPH receptor A10
EPYC epiphycan
ERC2-IT1 ERC2 intronic transcript 1
EREG epiregulin
ERO1L ERO1-like (S. cerevisiae)
EXOC3 exocyst complex component 3
EXOC3-AS1 EXOC3 antisense RNA 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM126A family with sequence similarity 126, member A
FASTKD3 FAST kinase domains 3
FBN1 fibrillin 1
FIGN fidgetin
FKBP9 FK506 binding protein 9, 63 kDa
FN1 fibronectin 1
FOXB1 forkhead box B1
FOXD2 forkhead box D2
FRMD5 FERM domain containing 5
FRS2 fibroblast growth factor receptor substrate 2
GAN gigaxonin
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGCX gamma-glutamyl carboxylase
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPNMB glycoprotein (transmembrane) nmb
GPR1 G protein-coupled receptor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GXYLT2 glucoside xylosyltransferase 2
HHAT hedgehog acyltransferase
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HNF4G hepatocyte nuclear factor 4, gamma
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSPA4L heat shock 70kDa protein 4-like
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICE1 interactor of little elongation complex ELL subunit 1
ICMT isoprenylcysteine carboxyl methyltransferase
IDS iduronate 2-sulfatase
IFITM4P interferon induced transmembrane protein 4 pseudogene
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL23A interleukin 23, alpha subunit p19
IMPG2 interphotoreceptor matrix proteoglycan 2
IPO13 importin 13
IRX2 iroquois homeobox 2
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITGA11 integrin, alpha 11
ITGB5 integrin, beta 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
IVL involucrin
KLHL34 kelch-like family member 34
KRT84 keratin 84, type II
KRTAP10-2 keratin associated protein 10-2
LAD1 ladinin 1
LAMP2 lysosomal-associated membrane protein 2
LBX1 ladybird homeobox 1
LIMK1 LIM domain kinase 1
LINC00113 long intergenic non-protein coding RNA 113
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC100192426 uncharacterized LOC100192426
LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene
LOXL1 lysyl oxidase-like 1
LRRC4 leucine rich repeat containing 4
LRRC59 leucine rich repeat containing 59
LRRC69 leucine rich repeat containing 69
MAGT1 magnesium transporter 1
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MANBA mannosidase, beta A, lysosomal
MAP7D2 MAP7 domain containing 2
MARCH9 membrane-associated ring finger (C3HC4) 9
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM1 Mdm1 nuclear protein homolog (mouse)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED10 mediator complex subunit 10
METTL1 methyltransferase like 1
METTL21B methyltransferase like 21B
MFSD11 major facilitator superfamily domain containing 11
MIOX myo-inositol oxygenase
MMP8 matrix metallopeptidase 8
MSANTD1 Myb/SANT-like DNA-binding domain containing 1
MSN moesin
MXRA8 matrix-remodelling associated 8
MYO10 myosin X
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAGA N-acetylgalactosaminidase, alpha-
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NEU1 sialidase 1 (lysosomal sialidase)
NEURL3 neuralized E3 ubiquitin protein ligase 3
NFE2L1 nuclear factor, erythroid 2-like 1
NMT1 N-myristoyltransferase 1
NNT nicotinamide nucleotide transhydrogenase
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOL9 nucleolar protein 9
NPY neuropeptide Y
NR2E1 nuclear receptor subfamily 2, group E, member 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NSUN5 NOP2/Sun domain family, member 5
NUP107 nucleoporin 107kDa
NXF4 nuclear RNA export factor 4 pseudogene
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR10J3 olfactory receptor, family 10, subfamily J, member 3
OR10V1 olfactory receptor, family 10, subfamily V, member 1
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OR52K1 olfactory receptor, family 52, subfamily K, member 1
OR6S1 olfactory receptor, family 6, subfamily S, member 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
OTULIN OTU deubiquitinase with linear linkage specificity
P4HB prolyl 4-hydroxylase, beta polypeptide
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAIP1 poly(A) binding protein interacting protein 1
PALM2 paralemmin 2
PAPD7 PAP associated domain containing 7
PAX1 paired box 1
PCDH7 protocadherin 7
PCDHGA4 protocadherin gamma subfamily A, 4
PDCD6 programmed cell death 6
PDGFC platelet derived growth factor C
PEX10 peroxisomal biogenesis factor 10
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLA1A phospholipase A1 member A
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLEKHN1 pleckstrin homology domain containing, family N member 1
PNPO pyridoxamine 5'-phosphate oxidase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PQLC2L PQ loop repeat containing 2-like
PROS1 protein S (alpha)
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTPRF protein tyrosine phosphatase, receptor type, F
QPRT quinolinate phosphoribosyltransferase
RAB21 RAB21, member RAS oncogene family
RANBP3L RAN binding protein 3-like
RAP1B RAP1B, member of RAS oncogene family
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RENBP renin binding protein
RER1 retention in endoplasmic reticulum sorting receptor 1
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
RTN4 reticulon 4
SATL1 spermidine/spermine N1-acetyl transferase-like 1
SBDSP1 Shwachman-Bodian-Diamond syndrome pseudogene 1
SCARB2 scavenger receptor class B, member 2
SCCPDH saccharopine dehydrogenase (putative)
SCN2B sodium channel, voltage gated, type II beta subunit
SCP2 sterol carrier protein 2
SCT secretin
SDF4 stromal cell derived factor 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERINC2 serine incorporator 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC22A17 solute carrier family 22, member 17
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35E3 solute carrier family 35, member E3
SLC35F3 solute carrier family 35, member F3
SLC35F5 solute carrier family 35, member F5
SLC35F6 solute carrier family 35, member F6
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNORA34 small nucleolar RNA, H/ACA box 34
SNORA61 small nucleolar RNA, H/ACA box 61
SOAT1 sterol O-acyltransferase 1
SOD3 superoxide dismutase 3, extracellular
SP7 Sp7 transcription factor
SPNS1 spinster homolog 1 (Drosophila)
SQLE squalene epoxidase
SQSTM1 sequestosome 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SSC5D scavenger receptor cysteine rich family, 5 domains
STK26 serine/threonine protein kinase 26
STXBP4 syntaxin binding protein 4
STYK1 serine/threonine/tyrosine kinase 1
STYXL1 serine/threonine/tyrosine interacting-like 1
SV2C synaptic vesicle glycoprotein 2C
SYNDIG1 synapse differentiation inducing 1
SYPL1 synaptophysin-like 1
SYPL2 synaptophysin-like 2
SYT16 synaptotagmin XVI
TAS2R3 taste receptor, type 2, member 3
TBL2 transducin (beta)-like 2
TEX2 testis expressed 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM104 transmembrane protein 104
TMEM106A transmembrane protein 106A
TMEM106B transmembrane protein 106B
TMEM117 transmembrane protein 117
TMEM119 transmembrane protein 119
TMEM184C transmembrane protein 184C
TMEM192 transmembrane protein 192
TMEM194A transmembrane protein 194A
TMEM55A transmembrane protein 55A
TMEM87A transmembrane protein 87A
TMEM95 transmembrane protein 95
TPP1 tripeptidyl peptidase I
TPPP tubulin polymerization promoting protein
TPRG1L tumor protein p63 regulated 1-like
TRIM2 tripartite motif containing 2
TRIO trio Rho guanine nucleotide exchange factor
TRIP13 thyroid hormone receptor interactor 13
TSFM Ts translation elongation factor, mitochondrial
TSPAN31 tetraspanin 31
TUBB3 tubulin, beta 3 class III
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN2 ubiquilin 2
ULBP3 UL16 binding protein 3
USP38 ubiquitin specific peptidase 38
VAC14 Vac14 homolog (S. cerevisiae)
VSIG10L V-set and immunoglobulin domain containing 10 like
WBSCR22 Williams Beuren syndrome chromosome region 22
WDFY1 WD repeat and FYVE domain containing 1
WIPF3 WAS/WASL interacting protein family, member 3
WNT10A wingless-type MMTV integration site family, member 10A
XRCC6BP1 XRCC6 binding protein 1
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YY2 YY2 transcription factor
ZBTB2 zinc finger and BTB domain containing 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC5 zinc finger, DHHC-type containing 5
ZDHHC9 zinc finger, DHHC-type containing 9
ZFPM2 zinc finger protein, FOG family member 2
ZFR zinc finger RNA binding protein
ZMPSTE24 zinc metallopeptidase STE24
ZNF114 zinc finger protein 114
ZNF292 zinc finger protein 292
ZNF622 zinc finger protein 622
ZNF70 zinc finger protein 70
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSWIM3 zinc finger, SWIM-type containing 3

low expression

Symbol Name
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATRIP ATR interacting protein
IP6K1 inositol hexakisphosphate kinase 1
MEX3C mex-3 RNA binding family member C
QRICH1 glutamine-rich 1
SMAD4 SMAD family member 4