Lung squamous cell carcinoma_LUSC_TCGA-34-8454-01A-11R-2326-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Lung squamous cell carcinoma_LUSC (The Cancer Genome Atlas)
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266 genes with high or low expression in Lung squamous cell carcinoma_LUSC_TCGA-34-8454-01A-11R-2326-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR3 atypical chemokine receptor 3
ACSM2B acyl-CoA synthetase medium-chain family member 2B
ACVR1C activin A receptor, type IC
ADAM28 ADAM metallopeptidase domain 28
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADGRG3 adhesion G protein-coupled receptor G3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIM2 absent in melanoma 2
ALB albumin
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ALPK1 alpha-kinase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD50 ankyrin repeat domain 50
ANXA2R annexin A2 receptor
APCS amyloid P component, serum
APLF aprataxin and PNKP like factor
APOF apolipoprotein F
APOL1 apolipoprotein L, 1
ARHGAP23 Rho GTPase activating protein 23
ASF1B anti-silencing function 1B histone chaperone
ASIC5 acid sensing (proton gated) ion channel family member 5
ASXL2 additional sex combs like transcriptional regulator 2
BARX2 BARX homeobox 2
BCO2 beta-carotene oxygenase 2
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BHLHE41 basic helix-loop-helix family, member e41
BIVM basic, immunoglobulin-like variable motif containing
BTF3 basic transcription factor 3
BTN3A2 butyrophilin, subfamily 3, member A2
C14ORF39 chromosome 14 open reading frame 39
C1RL complement component 1, r subcomponent-like
C2CD2 C2 calcium-dependent domain containing 2
C4ORF33 chromosome 4 open reading frame 33
C9ORF129 chromosome 9 open reading frame 129
C9ORF41 chromosome 9 open reading frame 41
CA12 carbonic anhydrase XII
CALML6 calmodulin-like 6
CAPN14 calpain 14
CCDC18 coiled-coil domain containing 18
CCDC88A coiled-coil domain containing 88A
CD7 CD7 molecule
CD82 CD82 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPBD1 CENPB DNA-binding domains containing 1
CENPC centromere protein C
CENPP centromere protein P
CENPW centromere protein W
CEP19 centrosomal protein 19kDa
CEP85L centrosomal protein 85kDa-like
CFH complement factor H
CLEC9A C-type lectin domain family 9, member A
CMTM1 CKLF-like MARVEL transmembrane domain containing 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CPA3 carboxypeptidase A3 (mast cell)
CPA6 carboxypeptidase A6
CRP C-reactive protein, pentraxin-related
CSNK1G2 casein kinase 1, gamma 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXADRP3 coxsackie virus and adenovirus receptor pseudogene 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXORF38 chromosome X open reading frame 38
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DAGLA diacylglycerol lipase, alpha
DCLRE1B DNA cross-link repair 1B
DEPDC7 DEP domain containing 7
DOC2B double C2-like domains, beta
DPYD dihydropyrimidine dehydrogenase
EEA1 early endosome antigen 1
EHF ets homologous factor
EVA1C eva-1 homolog C (C. elegans)
EYA3 EYA transcriptional coactivator and phosphatase 3
F13B coagulation factor XIII, B polypeptide
F9 coagulation factor IX
FAM102B family with sequence similarity 102, member B
FAM110C family with sequence similarity 110, member C
FAM157B family with sequence similarity 157, member B
FAM46A family with sequence similarity 46, member A
FAM71B family with sequence similarity 71, member B
FAM83A family with sequence similarity 83, member A
FAM99A family with sequence similarity 99, member A (non-protein coding)
FANCC Fanconi anemia, complementation group C
FAT3 FAT atypical cadherin 3
FCGBP Fc fragment of IgG binding protein
FLT3LG fms-related tyrosine kinase 3 ligand
FMO3 flavin containing monooxygenase 3
FMO4 flavin containing monooxygenase 4
FOXP3 forkhead box P3
FOXQ1 forkhead box Q1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GFI1 growth factor independent 1 transcription repressor
GNLY granulysin
GOLGA6L1 golgin A6 family-like 1
GOLGA6L6 golgin A6 family-like 6
GPR137 G protein-coupled receptor 137
GPR31 G protein-coupled receptor 31
GPSM2 G-protein signaling modulator 2
GRAMD4 GRAM domain containing 4
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GSDMC gasdermin C
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HAS2 hyaluronan synthase 2
HAS2-AS1 HAS2 antisense RNA 1
HDC histidine decarboxylase
HFE hemochromatosis
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-F major histocompatibility complex, class I, F
HLA-L major histocompatibility complex, class I, L (pseudogene)
HOXA7 homeobox A7
HOXA9 homeobox A9
HRG histidine-rich glycoprotein
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPG2 heparan sulfate proteoglycan 2
ICMT isoprenylcysteine carboxyl methyltransferase
ICOSLG inducible T-cell co-stimulator ligand
IDO1 indoleamine 2,3-dioxygenase 1
IL12RB2 interleukin 12 receptor, beta 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL22 interleukin 22
IL2RB interleukin 2 receptor, beta
IL5 interleukin 5
IL7 interleukin 7
INPP1 inositol polyphosphate-1-phosphatase
IRGM immunity-related GTPase family, M
IRX3 iroquois homeobox 3
ITGAD integrin, alpha D
ITSN2 intersectin 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KNG1 kininogen 1
KRT15 keratin 15, type I
KRT5 keratin 5, type II
KRTAP12-2 keratin associated protein 12-2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LENG9 leukocyte receptor cluster (LRC) member 9
LRG1 leucine-rich alpha-2-glycoprotein 1
LRRC3 leucine rich repeat containing 3
LY6D lymphocyte antigen 6 complex, locus D
MARCKS myristoylated alanine-rich protein kinase C substrate
MAST4 microtubule associated serine/threonine kinase family member 4
MATN2 matrilin 2
MBD3 methyl-CpG binding domain protein 3
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCM4 minichromosome maintenance complex component 4
MOV10 Mov10 RISC complex RNA helicase
MRPS27 mitochondrial ribosomal protein S27
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC4 mucin 4, cell surface associated
NBPF3 neuroblastoma breakpoint family, member 3
NCAM2 neural cell adhesion molecule 2
NCOA7 nuclear receptor coactivator 7
NDRG3 NDRG family member 3
NFIA nuclear factor I/A
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OR1F1 olfactory receptor, family 1, subfamily F, member 1
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2A4 olfactory receptor, family 2, subfamily A, member 4
PALMD palmdelphin
PAOX polyamine oxidase (exo-N4-amino)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCP4L1 Purkinje cell protein 4 like 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PFKL phosphofructokinase, liver
PHF21A PHD finger protein 21A
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITX2 paired-like homeodomain 2
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLG plasminogen
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1
PNMA5 paraneoplastic Ma antigen family member 5
POU6F2 POU class 6 homeobox 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRAMEF10 PRAME family member 10
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTCD2 pentatricopeptide repeat domain 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVRL3 poliovirus receptor-related 3
RAB41 RAB41, member RAS oncogene family
RANBP3L RAN binding protein 3-like
RERG RAS-like, estrogen-regulated, growth inhibitor
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RNF39 ring finger protein 39
RREB1 ras responsive element binding protein 1
SEPP1 selenoprotein P, plasma, 1
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SFRP4 secreted frizzled-related protein 4
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6
SLC10A7 solute carrier family 10, member 7
SLC22A20 solute carrier family 22, member 20
SMC1A structural maintenance of chromosomes 1A
SMC6 structural maintenance of chromosomes 6
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SNORA44 small nucleolar RNA, H/ACA box 44
SNORA71B small nucleolar RNA, H/ACA box 71B
SSPN sarcospan
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1-GTF2A1L STON1-GTF2A1L readthrough
SUOX sulfite oxidase
TAPBP TAP binding protein (tapasin)
TAT tyrosine aminotransferase
TCF19 transcription factor 19
TIFA TRAF-interacting protein with forkhead-associated domain
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLX3 T-cell leukemia homeobox 3
TMEM109 transmembrane protein 109
TMEM143 transmembrane protein 143
TMEM171 transmembrane protein 171
TMEM39B transmembrane protein 39B
TMPRSS11A transmembrane protease, serine 11A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP3 TNFAIP3 interacting protein 3
TPSD1 tryptase delta 1
TRIB2 tribbles pseudokinase 2
TRIM31 tripartite motif containing 31
TRIM74 tripartite motif containing 74
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBD ubiquitin D
UGCG UDP-glucose ceramide glucosyltransferase
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VAV3 vav 3 guanine nucleotide exchange factor
WDR92 WD repeat domain 92
WNT3A wingless-type MMTV integration site family, member 3A
ZBTB45 zinc finger and BTB domain containing 45
ZFP36L1 ZFP36 ring finger protein-like 1
ZHX1 zinc fingers and homeoboxes 1
ZNF324B zinc finger protein 324B
ZNF347 zinc finger protein 347
ZNF417 zinc finger protein 417
ZNF418 zinc finger protein 418
ZNF480 zinc finger protein 480
ZNF497 zinc finger protein 497
ZNF543 zinc finger protein 543
ZNF548 zinc finger protein 548
ZNF611 zinc finger protein 611
ZNF628 zinc finger protein 628
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749
ZNF776 zinc finger protein 776
ZNF813 zinc finger protein 813
ZNF837 zinc finger protein 837

low expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
MKRN2 makorin ring finger protein 2
PBDC1 polysaccharide biosynthesis domain containing 1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2